Ensysce Biosciences Secures $4 Million Financing, Unlocking Up to $20 Million in Total Financing to Advance Breakthrough Pain Programs
Rhea-AI Summary
Ensysce Biosciences (NASDAQ:ENSC) closed a $4.0 million convertible preferred financing on November 17, 2025, with the potential for up to an additional $16.0 million in future tranches over the next 24 months (up to $20.0 million total).
The initial tranche carries a fixed conversion price of $2.50 per share, an alternate conversion based on average common stock prices, and 50% warrant coverage exercisable at the fixed conversion price for five years. Proceeds will accelerate the Phase 3 development of PF614 and support corporate initiatives, with management citing Phase 3 completion or market-readiness targets in the 18–24 month timeframe.
Positive
- $4.0M closed now with up to $16.0M available
- Fixed conversion price $2.50 on the initial tranche
- 50% warrant coverage exercisable for five years
- Funding designated to accelerate PF614 Phase 3 within 18–24 months
Negative
- Convertible preferred and warrants create shareholder dilution
- Up to $16.0M of future tranches over 24 months may increase dilution
- Alternate conversion tied to average common stock price adds conversion variability
News Market Reaction
On the day this news was published, ENSC declined 4.85%, reflecting a moderate negative market reaction. Argus tracked a peak move of +21.0% during that session. Argus tracked a trough of -17.8% from its starting point during tracking. Our momentum scanner triggered 4 alerts that day, indicating moderate trading interest and price volatility. This price movement removed approximately $312K from the company's valuation, bringing the market cap to $6M at that time.
Data tracked by StockTitan Argus on the day of publication.
~Funding supports Phase 3 clinical development of PF614 and continued innovation in abuse- and overdose-resistant analgesics~
SAN DIEGO, CA / ACCESS Newswire / November 17, 2025 / Ensysce Biosciences, Inc. (NASDAQ:ENSC)("Ensysce" or the "Company"), pioneering novel solutions for severe pain with built-in abuse and overdose protection, today announced the closing of a
The capital will accelerate the Phase 3 clinical program for PF614, Ensysce's flagship analgesic candidate, while supporting general corporate initiatives. The initial
Key Highlights:
$4 Million Closed Now,$16 Million Available: Providing funding flexibility to advance critical programs.Phase 3 Acceleration: PF614 clinical trials moving toward market readiness within 18-24 months.
Investor Confidence: Current backers continue to support Ensysce's mission-driven innovation.
Dr. Kirkpatrick, CEO of Ensysce Biosciences, stated, "This financing demonstrates strong investor confidence in Ensysce's vision: safe, effective analgesics that re-invent pain management. With PF614 on track for Phase 3 completion in the next 18 months and federal grant support for our MPAR program, we are moving closer to delivering transformative treatments for patients in urgent need."
About Ensysce Biosciences
Ensysce Biosciences is a clinical stage company with a goal of disrupting the analgesic landscape by introducing a new class of highly novel opioids for the treatment of severe pain. Leveraging its Trypsin-Activated Abuse Protection (TAAPTM) and Multi-Pill Abuse Resistance (MPAR®) platforms, the Company is developing unique, tamper-proof treatment options for pain that minimize the risk of both drug abuse and overdose. Ensysce's products are anticipated to provide safer options to treat patients suffering from severe pain and assist in preventing deaths caused by medication abuse. Ensysce's pipeline is backed by a robust global intellectual property portfolio, offering hope to patients and providers confronting the challenges of pain management. Learn more at www.ensysce.com.
Forward-Looking Statements
Statements contained in this press release that are not purely historical may be deemed to be forward-looking statements for the purposes of the safe harbor provisions under The Private Securities Litigation Reform Act of 1995 and other federal securities laws. Without limiting the foregoing, the use of words such as "may," "intends," "can," "might," "will," "expect," "plan," "possible," "believe" and other similar expressions are intended to identify forward-looking statements. The product candidates discussed are in clinic and not approved and there can be no assurance that the clinical programs will be successful in demonstrating safety and/or efficacy, that Ensysce will not encounter problems or delays in clinical development, or that any product candidate will ever receive regulatory approval or be successfully commercialized. All forward-looking statements are based on estimates and assumptions by Ensysce's management that, although Ensysce believes to be reasonable, are inherently uncertain. All forward-looking statements are subject to risks and uncertainties that may cause actual results to differ materially from those that Ensysce expected. In addition, Ensysce's business is subject to additional risks and uncertainties, including among others, the initiation and conduct of preclinical studies and clinical trials; the timing and availability of data from preclinical studies and clinical trials; expectations for regulatory submissions and approvals; potential safety concerns related to, or efficacy of, Ensysce's product candidates; the availability or commercial potential of product candidates; the ability of Ensysce to fund its continued operations, including its planned clinical trials; the dilutive effect of stock issuances from our fundraising; and Ensysce's and its partners' ability to perform under their license, collaboration and manufacturing arrangements. These statements are also subject to a number of material risks and uncertainties that are described in Ensysce's most recent quarterly report on Form 10-Q and current reports on Form 8-K, available free of charge at the SEC's website at www.sec.gov. Any forward-looking statement speaks only as of the date on which it was made. Ensysce undertakes no obligation to publicly update or revise any forward-looking statement, whether as a result of new information, future events or otherwise, except as required under applicable law.
Ensysce Biosciences Company Contact:
Lynn Kirkpatrick, Ph.D.
Chief Executive Officer
(858) 263-4196
Ensysce Biosciences Investor Relations Contact:
Shannon Devine
MZ North America
Main: 203-741-8811
ENSC@mzgroup.us
SOURCE: Ensysce Biosciences Inc.
View the original press release on ACCESS Newswire
FAQ
What financing did Ensysce (ENSC) announce on November 17, 2025?
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What are the conversion and warrant terms in Ensysce's (ENSC) financing?
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