Esperion Therape Stock Price, News & Analysis

Esperion (NASDAQ: ESPR) announced a publication in JAMA Cardiology detailing a pooled efficacy analysis from four Phase 3 studies of NEXLETOL, an oral LDL-cholesterol lowering medication. The studies involved 3,623 patients and demonstrated that NEXLETOL, when added to statin therapy, significantly lowered LDL-C by 18% versus placebo, and by 24% in statin-intolerant patients. The drug is intended for those with familial hypercholesterolemia or established cardiovascular disease needing additional LDL-C reduction. The safety profile showed similar adverse event rates between NEXLETOL and placebo.

Esperion (NASDAQ: ESPR) announced a $150 million milestone payment from Daiichi Sankyo Europe (DSE), which will be received this month due to the transfer of Marketing Authorization Approvals (MAAs) for NILEMDO and NUSTENDI. This agreement allows DSE to commercialize the drugs in Europe. With this payment, Esperion will have received $300 million in total milestone payments. Additionally, Esperion is conducting the CLEAR Cardiovascular Outcomes Trial to assess the impact of bempedoic acid on cardiovascular health for patients unable to tolerate statins.

Esperion (NASDAQ: ESPR) presented a pooled analysis from four Phase 3 clinical studies of NEXLETOL at the American Diabetes Association's 80th Scientific Sessions. The study revealed significant reductions in LDL cholesterol and other cholesterol markers among patients with diabetes, prediabetes, and normoglycemia. NEXLETOL also lowered hemoglobin A1c by 0.19%. The safety profile was consistent across all glycemic status subgroups. This analysis supports the efficacy and safety of NEXLETOL, which is a first-in-class oral medication approved for LDL-C lowering.

Esperion (NASDAQ: ESPR) received notice that the Institute for Clinical and Economic Review (ICER) will assess non-statin medicines for hypercholesterolemia, including the cost-effectiveness of NEXLETOL, with a report expected by February 2021. The company has achieved over 70% commercial and 40% Medicare Part D formulary coverage for NEXLETOL, aiming for affordable access to its treatment. Esperion is committed to patient access and has initiated the CLEAR Cardiovascular Outcomes Trial to evaluate NEXLETOL’s effects on cardiovascular events in statin-averse patients.

Esperion (NASDAQ: ESPR) announced that its CEO, Tim M. Mayleben, will participate in an analyst-led fireside chat at the Goldman Sachs 41st Annual Global Healthcare Conference on June 11, 2020, at 4:40 p.m. ET. The event will be available via a live audio webcast on Esperion's investor relations website, with a replay accessible for 90 days afterward. Esperion is dedicated to developing oral medicines focused on lowering LDL-C to combat cardiovascular diseases, which affect millions in the U.S. Due to the high prevalence of elevated LDL-C levels, the company aims to offer effective solutions to improve patient outcomes.

Esperion (NASDAQ: ESPR) announced the launch of NEXLIZET^TM (bempedoic acid and ezetimibe), the first approved non-statin LDL-C lowering combination medicine, now available in U.S. pharmacies. The drug achieves a mean LDL-C reduction of 38% when added to statins, with minimal paperwork for healthcare providers. NEXLIZET aims to set a new standard for affordability with broad payer coverage and a low co-pay for eligible patients. The launch has been accelerated by one month in response to healthcare provider requests, emphasizing the urgent need for additional cholesterol-lowering options.

Esperion (NASDAQ: ESPR) announced the grant of 88,902 restricted stock units (RSUs) to 194 new employees as part of its 2017 Inducement Equity Incentive Plan. The RSUs will vest over four years, with 25% after one year and the remaining 75% quarterly. This grant aims to attract talent as the company continues its mission of developing LDL-C lowering medicines to address cardiovascular disease. The press release contains forward-looking statements regarding clinical development and commercialization plans that carry inherent risks and uncertainties.

Esperion (NASDAQ: ESPR) announced that CEO Tim M. Mayleben will engage in an analyst-led fireside chat at the BofA Securities 2020 Healthcare Conference on May 12, 2020, at 9:00 a.m. ET. Interested parties can access a live audio webcast from the investor relations section of Esperion's website. The discussion will emphasize the company's efforts in cholesterol management, specifically targeting LDL-C levels. Esperion's mission is to develop oral medications that can significantly reduce LDL-C, combating the prevalence of cardiovascular diseases.

Esperion (NASDAQ:ESPR) announced the U.S. marketing approvals for NEXLETOL™ and NEXLIZET™ tablets, with NEXLETOL™ available from March 30 and NEXLIZET™ from June 4, 2020. The company reported first-ever product sales revenue of $1.8 million in Q1 2020, alongside a net loss of $78.2 million. Cash reserves totaled $158 million, bolstered by a $60 million collaboration payment. Esperion also anticipates a record revenue year driven by emerging sales and collaborations. A conference call is scheduled for May 6 to discuss the business outlook.