4D Molecular Therapeutics Inc. Stock Price, News & Analysis

4D Molecular Therapeutics (Nasdaq: FDMT) said its management team will participate in a fireside chat and be available for one-on-one meetings at the Jefferies 2025 London Healthcare Conference.

The presentation is scheduled for Tuesday, Nov 18, 2025 at 9:00 a.m. GMT. A live webcast will be available, and archived copies will be posted for up to one year in the Investors section of the company's website.

4D Molecular Therapeutics (Nasdaq: FDMT) priced an underwritten common stock offering to raise approximately $100 million gross. The company will sell 8,385,809 common shares at $10.51 per share and, in lieu of shares for certain investors, 1,128,949 pre-funded warrants at $10.5099 each (exercise price $0.0001).

The offering is expected to close on November 7, 2025, subject to customary closing conditions; gross proceeds are before underwriting discounts, commissions and offering expenses. Leerink Partners, Evercore ISI and Cantor are joint book-running managers; RBC Capital Markets is co-manager.

4DMT (Nasdaq: FDMT) reported positive interim 1.5–3.5 year PRISM Phase 1/2 data for 4D-150 in wet AMD showing consistent maintenance of visual acuity, durable control of retinal anatomy, and large reductions in supplemental anti-VEGF injections through up to 2 years.

Key metrics include treatment-burden reductions up to 94% versus projected aflibercept, a dose response favoring the Phase 3 dose 3E10 vg/eye, a 2.8% rate of transient mild intraocular inflammation within 28 weeks, and Phase 3 enrollment > 200 patients with global 4FRONT-2 on track for completion in H2 2026.

4DMT (Nasdaq: FDMT) entered an exclusive license agreement with Otsuka to develop and commercialize 4D-150 for wet AMD and DME across the greater Asia-Pacific region, including Japan.

Key terms include an $85 million upfront cash payment, an expected ≥$50 million of cost sharing over three years for global development, up to $336 million in regulatory and commercial milestones, and tiered double-digit royalties on net sales in Otsuka’s territories. 4DMT retains development and commercialization rights outside APAC and will continue to lead global Phase 3 activities; APAC sites for 4FRONT-2 are expected to open by year-end, with Japan sites expected in January 2026.

4D Molecular Therapeutics (Nasdaq: FDMT) announced that on October 14, 2025 its compensation committee granted 25,450 Restricted Stock Units (RSUs) to three new non-executive employees under the company’s 2025 Employment Inducement Award Plan.

The inducement plan was approved by the board in February 2025 and is being used under Nasdaq Rule 5635(c)(4) to grant equity awards to attract new hires. The announcement identifies the grant date and plan authority but does not disclose recipient names, vesting terms, or share-count impact.

4D Molecular Therapeutics (Nasdaq: FDMT) said management will participate in panel discussions at Chardan's 9th Annual Genetic Medicines Conference on October 21, 2025.

Management will attend two panels: "In Vivo Gene Therapy: Breaking into Competitive Ophthalmic Indications" at 9:30 a.m. ET and "In Vivo Gene Therapies in the Lung: Treating CF and Beyond" at 2:00 p.m. ET. Webcasts are available, and archived copies will be posted for up to one year in the Investors section at https://ir.4dmoleculartherapeutics.com/events. Company representatives will also be available for one-on-one meetings.

4D Molecular Therapeutics (NASDAQ:FDMT) announced the Cystic Fibrosis Foundation will provide up to $11 million in additional equity funding, with an initial tranche of $7.5 million closed in October 2025, and technical support to accelerate development of 4D-710 for cystic fibrosis lung disease. The CF Foundation has now committed nearly $32 million to 4DMT CF programs to date. Funding supports a Phase 1 redosing cohort, ongoing Phase 2 enrollment at a selected dose of 2.5E14 vg, and Phase 3 readiness. Interim Phase 1 durability data and a program update are expected by year-end 2025.

4D Molecular Therapeutics (Nasdaq: FDMT), a late-stage biotechnology company, has granted 40,900 Restricted Stock Units (RSUs) to four new non-executive employees. The compensation committee approved these inducement grants on September 9, 2025.

The RSUs were awarded under the Company's 2025 Employment Inducement Award Plan, which was established in February 2025 under Nasdaq Rule 5635(c)(4) to provide equity incentives for new employee recruitment.

4D Molecular Therapeutics (NASDAQ: FDMT) announced key leadership changes to strengthen its late-stage clinical development capabilities. Dr. Julie Clark has been promoted to Chief Medical Officer, bringing over 20 years of retina and clinical development experience, including involvement in 10 BLA-enabling studies and six Phase 3 trials. The company also welcomed Dr. Liansheng Zhu as SVP of Biometrics and Data Quality.

The company's 4FRONT-1 Phase 3 trial for 4D-150 is progressing ahead of schedule, with enrollment completion expected in Q1 2026. Additionally, FDMT has added distinguished retina industry advisors, including Glenn P. Sblendorio, Dr. Cal Roberts, and Dr. Wiley A. Chambers, to enhance their development and commercialization expertise. Dr. Robert Kim has stepped down as Chief Medical Officer.