Fulcrum Therapeutics Stock Price, News & Analysis

Fulcrum Therapeutics (Nasdaq: FULC), a clinical-stage biopharmaceutical company, has granted non-statutory stock options to two new employees under its 2022 Inducement Stock Incentive Plan. The grants were made in accordance with Nasdaq Listing Rule 5635(c)(4). One employee received 350,000 options at an exercise price of $9.34 per share, effective August 19, 2024. Another employee was granted 270,000 options at $8.43 per share, effective July 29, 2024. Both options have a ten-year term and vest over four years, with 25% vesting on the first anniversary and the remaining 75% vesting quarterly over the next three years, subject to continued employment.

Fulcrum Therapeutics (NASDAQ: FULC) has strengthened its leadership team with two key appointments. Isabel Kalofonos joins as Chief Commercial Officer, bringing extensive experience in rare disease drug launches, including ELAHERE® and TAKHZYRO®. Heather Faulds becomes Chief Regulatory Affairs & Quality Assurance Officer, with a strong background in neuromuscular diseases and regulatory strategies.

These appointments are important as Fulcrum prepares for the potential New Drug Application (NDA) submission and commercial launch of losmapimod for the treatment of FSHD, a rare genetic disease. Kalofonos's commercial expertise and Faulds's regulatory experience, particularly with the rapid FDA approval of SPINRAZA®, position Fulcrum to transition into a commercial-stage biotechnology company.

Fulcrum Therapeutics (Nasdaq: FULC), a clinical-stage biopharmaceutical company, has announced the granting of non-statutory stock options to four new employees. The grants were made under the company's 2022 Inducement Stock Incentive Plan, in accordance with Nasdaq Listing Rule 5635(c)(4). Three employees received a total of 131,300 options at an exercise price of $8.46 per share, while one employee received 150,000 options at $8.87 per share. These options have a ten-year term and vest over four years, with 25% vesting on the first anniversary and the remaining 75% vesting quarterly over the following three years, subject to continued employment.

Fulcrum Therapeutics (NASDAQ: FULC) reported its Q2 2024 financial results and business highlights. Key points include:

1. The company is on track to report topline data for the Phase 3 REACH trial of losmapimod in FSHD by end of October 2024.

2. Fulcrum entered a collaboration and ex-U.S. license agreement with Sanofi for losmapimod development and commercialization.

3. Q2 2024 financials: $273.8 million in cash and equivalents, $80 million in collaboration revenue, and net income of $55.4 million.

4. The Phase 1b PIONEER trial of pociredir for sickle cell disease is progressing.

5. Fulcrum expects its current cash position to fund operations into 2027.

Fulcrum Therapeutics (Nasdaq: FULC), a clinical-stage biopharmaceutical company focused on developing small molecules for genetically defined rare diseases, has announced its plans to release second quarter 2024 financial results on Wednesday, July 31, 2024, before U.S. financial markets open. The company will host a conference call and webcast at 8:00 a.m. ET on the same day to discuss the results and provide updates on recent corporate developments.

Interested parties can register for the conference call through a provided link, which will give them dial-in details and a unique PIN for access. An audio webcast will also be available through the company's Investor Relations section on their website.

Fulcrum Therapeutics (Nasdaq: FULC) will present at the 31st Annual FSHD Society International Research Congress in Denver, Colorado, on June 13-14, 2024. The presentations will cover various aspects of the Phase 3 REACH trial of losmapimod, a treatment for facioscapulohumeral muscular dystrophy (FSHD). Key presentations include an abstract on the baseline characteristics of trial participants, efficacy and progression of FSHD assessed by reachable workspace, and safety and tolerability of losmapimod. These findings will be disseminated through both poster and oral presentations, featuring various researchers, including Nicol Voermans, Joost Kools, Mihaela Levitchi Benea, and Lena Hubig.

Fulcrum Therapeutics, a clinical-stage biopharmaceutical company, announced its participation in Goldman Sachs’ 45th Annual Healthcare Conference. Scheduled for June 10, 2024, at 10:00 a.m. ET, the company's management will engage in a fireside chat. A webcast of the presentation will be accessible via Fulcrum's website and available for replay for at least 30 days post-event. Fulcrum focuses on developing small molecules aimed at improving the lives of patients with genetically defined rare diseases.

Fulcrum Therapeutics, a biopharmaceutical company, announced recent business highlights and financial results for Q1 2024. They entered a collaboration with Sanofi for losmapimod, expect Phase 3 trial results in Q4 2024, appointed a new chief medical officer, and reported positive data on their Phase 2 study. Fulcrum's cash position decreased, with collaboration revenue at zero. R&D expenses increased, G&A expenses decreased, and net loss rose. Cash runway guidance extends into 2027.

Fulcrum Therapeutics has partnered with Sanofi for the development and commercialization of Losmapimod in Facioscapulohumeral Muscular Dystrophy (FSHD). Sanofi gains exclusive rights outside the U.S., while Fulcrum retains rights in the U.S. Fulcrum will receive an $80.0 million upfront payment, with potential milestones of $975.0 million and royalties. The collaboration combines Fulcrum's FSHD expertise with Sanofi's global reach.