Welcome to our dedicated page for Gain Therapeutics news (Ticker: GANX), a resource for investors and traders seeking the latest updates and insights on Gain Therapeutics stock.
Gain Therapeutics, Inc. develops allosteric small molecule therapies for neurodegenerative and other difficult-to-treat diseases. The company’s lead candidate, GT-02287, is being developed for Parkinson’s disease with or without a GBA1 mutation and is designed as a brain-penetrant allosteric enzyme modulator of glucocerebrosidase, or GCase.
Recurring news for GANX includes financial results, corporate updates, clinical and biomarker data for GT-02287, FDA and IND-related communications, and scientific presentations at Parkinson’s and neurodegeneration conferences. Company updates also cover the Magellan™ drug discovery platform, preclinical GCase modulator programs such as GT-04686, and pipeline areas including lysosomal storage disorders, metabolic diseases and solid tumors.
Gain Therapeutics (Nasdaq: GANX) provided a scientific update on its Krabbe disease program, highlighting statistically significant increases in the GALC enzyme and a reduction in toxic substrate psychosine. This breakthrough suggests potential treatment options for patients with Krabbe disease, a severe genetic disorder affecting the nervous system. Initial tests on compounds showed promise in reducing psychosine levels. The next phase involves further evaluation of compounds in complex in vitro models.
Gain Therapeutics, Inc. (Nasdaq: GANX) will present a corporate overview at the Imagine AI + Healthcare Investor Summit on December 7, 2021. CEO Eric Richman and Chief Scientific Officer Xavier Barril, Ph.D., will discuss Gain's innovative approach to targeting allosteric binding sites for neurodegenerative diseases and lysosomal storage disorders. The summit is an opportunity for investors to engage with various companies and learn about advancements in AI within healthcare.
Gain Therapeutics (NASDAQ: GANX) reported its Q3 2021 financial results and announced key corporate developments. The company has $40.98 million in cash, providing a strong financial runway into the second half of 2023. Significant progress was made in patient-derived iPSC studies, showing STAR compounds positively affecting Gaucher and Parkinson's disease markers. Matthias Alder was appointed COO, and a five-member Scientific Advisory Board was established to advance the company’s clinical programs. Q3 revenues increased to $27 thousand, while net loss rose to $4.66 million, reflecting higher R&D and administrative expenses.
Gain Therapeutics (Nasdaq: GANX) presented promising preclinical data on GT-02287, a compound targeting glucocerebrosidase (GCase) for Parkinson’s Disease, at the Society for Neuroscience Annual Meeting. The findings revealed that GT-02287 significantly reduced alpha-synuclein pathology and neuroinflammation while improving behavioral deficits in an animal model. With a favorable toxicity profile, this orally bioavailable compound shows potential in addressing unmet needs for patients suffering from Parkinson’s, particularly those with GBA1 mutations.
Gain Therapeutics (Nasdaq: GANX) announced breakthrough results from a study on its STAR compounds, GT-02287 and GT-02329, for treating Gaucher and GBA1 Parkinson's Disease. Conducted at the University of Maryland, the study demonstrated significant increases in GCase protein levels in iPSC-derived dopaminergic neurons and reductions in phosphorylated α-synuclein. These findings reveal a potential new approach for neurodegenerative disorders, showing a 129% increase in GCase enzyme levels. The company plans to initiate IND-enabling studies soon, promising hope for patients with alpha synucleinopathies.
Gain Therapeutics (Nasdaq: GANX) announced participation at the 12th Annual Jefferies London Healthcare Conference on November 16-19, 2021. CEO Eric Richman will present on November 17 from 9:20 to 9:55 a.m. GMT. Investors can engage in one-on-one meetings either in-person or virtually. The presentation will focus on Gain's innovative drug development strategies targeting neurodegenerative diseases and lysosomal storage disorders through its proprietary SEE-Tx™ platform. For more details, visit Gain’s official website.
Gain Therapeutics, Inc. (Nasdaq: GANX) announced that its management team will present at key medical conferences, including The Michael J. Fox Foundation’s Parkinson’s Disease Therapeutics Webinars on November 10, 2021, and The Society of Neuroscience Annual Meeting on November 9, 2021. The webinars aim to showcase advancements in Parkinson’s research, featuring topics like drug discovery and brain-penetrant allosteric regulators. These sessions will provide insights into ongoing research supported by the foundation. For registration and further information, visit the respective conference websites.
Gain Therapeutics has established a Scientific Advisory Board (SAB) to enhance its research efforts in neurodegenerative diseases and lysosomal storage disorders. Dr. Luca Benatti has been appointed as the chair, joined by esteemed members including Dr. Samuel Broder and Dr. Joanne Taylor. These experts bring decades of significant industry experience to shape the company's clinical strategies as it progresses its lead program in Parkinson’s Disease toward trials. Gain aims to redefine drug discovery through its innovative SEE-Tx™ platform.
Gain Therapeutics, Inc. (Nasdaq: GANX) recently appointed Matthias Alder as Chief Operating Officer to enhance its operational capabilities and prepare for clinical trials of its lead program targeting Gaucher and Parkinson's Diseases, expected in 2022. Alder brings over 25 years of industry experience, previously serving as Chief Business Officer at Autolus Therapeutics. CEO Eric Richman expressed confidence in Alder's ability to scale Gain's platform and expand partnerships. The company focuses on allosteric binding sites using its innovative SEE-Tx™ discovery platform to address neurodegenerative diseases.
Gain Therapeutics, Inc. (Nasdaq: GANX) will participate in the Cantor Virtual Global Healthcare Conference from September 27th-30th, showcasing its innovative approach to targeting allosteric binding sites for neurodegenerative diseases. CEO Eric Richman will present on September 30, from 8:00 to 8:30 a.m. ET, with a webcast available for interested investors. Gain Therapeutics aims to redefine drug discovery using its SEE-Tx™ platform, unlocking new treatment options for challenging disorders.