Welcome to our dedicated page for Gilead Sciences news (Ticker: GILD), a resource for investors and traders seeking the latest updates and insights on Gilead Sciences stock.
Gilead Sciences, Inc. (Nasdaq: GILD) is a biopharmaceutical company focused on medicines for HIV, viral hepatitis, COVID‑19, cancer and inflammation. The GILD news feed highlights how the company’s research, collaborations and policy decisions translate into clinical programs, regulatory milestones and access initiatives across these therapeutic areas.
Investors and healthcare observers following GILD news will see regular updates on Gilead’s HIV portfolio, including clinical trial readouts such as the Phase 3 ARTISTRY‑1 and ARTISTRY‑2 studies of an investigational single‑tablet regimen combining bictegravir and lenacapavir for virologically suppressed adults with HIV. News also covers developments related to lenacapavir as a long‑acting option for HIV prevention and treatment, as well as agreements affecting key products like Biktarvy, including patent settlements disclosed by the company.
Oncology and cell therapy news is another major theme. Through Kite, a Gilead company, GILD‑related releases feature data on Yescarta for relapsed or refractory large B‑cell lymphoma, next‑generation bicistronic CAR T‑cell candidates KITE‑753 and KITE‑363 for B‑cell lymphomas, and anitocabtagene autoleucel (anito‑cel) for relapsed or refractory multiple myeloma. Updates often include efficacy and safety results from pivotal and early‑stage trials, as well as details on collaborations such as the partnership with Arcellx on anito‑cel and the research collaboration with OncoNano Medicine on ON‑BOARD encapsulation technology.
Gilead news also reflects broader corporate and policy activity, including agreements with the U.S. government related to drug pricing and access, philanthropic grants from the Gilead Foundation for metastatic breast cancer support, leadership appointments, investor conference presentations and quarterly financial announcements. Bookmark this page to monitor how these scientific, commercial, governance and access‑related developments shape the ongoing story of GILD.
Gilead's Kite presents five-year results from the pivotal ZUMA-1 trial of Yescarta (axicabtagene ciloleucel) for refractory large B-cell lymphoma. Notably, 42.6% of patients are alive after five years, with a remarkable 92% of those needing no further treatment, indicating a potential cure. Among those who achieved a complete response, the five-year overall survival rate is 64.4%. These findings were shared at the 63rd ASH Annual Meeting. Medical experts underscore this as a transformative breakthrough in treatment, contrasting the average six-month life expectancy for these patients.
Gilead Sciences announced results from the ZUMA-7 trial, the first Phase 3 study of CAR T-cell therapy for relapsed or refractory large B-cell lymphoma (LBCL). Yescarta showed superior two-year event-free survival (EFS) rates of 40.5% compared to 16.3% for the standard of care (SOC). The study enrolled 359 patients and demonstrated improved quality of life for those treated with Yescarta. Regulatory filings to expand Yescarta's indication are in progress, with the FDA granting Priority Review status, targeting a decision by April 1, 2022.
Gilead Sciences (GILD) presented new data from the Phase 3 ASCENT study on Trodelvy (sacituzumab govitecan) in Black patients with relapsed or refractory metastatic triple-negative breast cancer (TNBC). The study showed a 56% reduction in the risk of disease worsening or death, with a median progression-free survival (PFS) of 5.4 months versus 2.2 months for chemotherapy. Overall survival also improved to 13.8 months compared to 8.5 months for chemotherapy. Trodelvy demonstrated a higher overall response rate of 32% compared to 6% for chemotherapy. Safety profiles were consistent with earlier findings.
Gilead Sciences has selected AWS as its preferred cloud provider to enhance its clinical trial design and data-driven decision-making capabilities. This collaboration will leverage AWS's machine learning and analytics to refine Gilead's drug pipeline while ensuring patient privacy and data security. Gilead will also implement SAP S/4HANA for its enterprise resource planning, aiming for increased operational efficiency. Additionally, over 50% of its data center footprint will be migrated to AWS, which supports IT transformation and improved disaster recovery processes.
Gilead Sciences (NASDAQ: GILD) will present new data from the Phase 3 ASCENT study of Trodelvy at the San Antonio Breast Cancer Symposium (December 7-10). The analyses focus on treatment outcomes for Black patients with metastatic triple-negative breast cancer (TNBC) and post-progression therapy outcomes. Trodelvy is indicated for patients with metastatic TNBC who have received prior systemic therapies. The study highlights Trodelvy's potential in addressing high unmet needs in cancer care.
The European Commission has granted marketing authorization for Trodelvy (sacituzumab govitecan), developed by Gilead Sciences (GILD), for treating adult patients with metastatic triple-negative breast cancer (TNBC) after two or more therapies. The approval is supported by Phase 3 ASCENT study results, showing a 49% reduction in death risk and improved overall survival (11.8 months vs. 6.9 months). This is a significant treatment option for this aggressive cancer type, which has a five-year survival rate of only 12%. Trodelvy is also approved in several other countries.
Gilead Sciences (GILD) has submitted a Biologics License Application (BLA) for bulevirtide, an investigational treatment for chronic hepatitis delta virus (HDV) infection in adults with compensated liver disease. If approved, it will be the first treatment option in the U.S. for this condition. The submission is backed by Phase 2 and 3 study data, showing 36.7% response after 24 weeks with bulevirtide 2 mg. The drug has received Breakthrough Therapy and Orphan Drug designations from the FDA, emphasizing its potential significance in addressing severe liver disease.
Gilead Sciences (Nasdaq: GILD) announced its participation in the Evercore ISI Annual HealthCONx Conference on Thursday, December 2 at 2:40 PM ET. Investors can access a live webcast on the company’s investors page, with a replay available for 30 days post-presentation. Gilead is a biopharmaceutical leader committed to innovative treatments for serious diseases including HIV, viral hepatitis, and cancer, operating in over 35 countries from its headquarters in Foster City, California.
Gilead Sciences has exercised options for three clinical-stage programs from Arcus Biosciences, including anti-TIGIT agents domvanalimab and AB308, as well as etrumadenant and quemliclustat. This move involves $725 million in option payments to Arcus. The companies are set to co-develop these candidates, share global costs, and explore innovative treatment combinations. Antitrust clearance is required, with expected closure by year-end.
Gilead Sciences has exercised options for three clinical-stage programs from Arcus Biosciences, including domvanalimab, AB308, etrumadenant, and quemliclustat. The agreement, subject to antitrust clearance, results in Arcus receiving