Welcome to our dedicated page for Monte Rosa Therapeutics news (Ticker: GLUE), a resource for investors and traders seeking the latest updates and insights on Monte Rosa Therapeutics stock.
Monte Rosa Therapeutics, Inc. (Nasdaq: GLUE) is a clinical-stage biotechnology leader pioneering molecular glue degraders (MGDs) to treat complex diseases. This page provides investors and researchers with centralized access to official company announcements, including clinical trial updates, research milestones, and strategic collaborations.
Key resources include: Real-time updates on drug development progress, regulatory filings, and peer-reviewed data publications. Users will find curated news on oncology and autoimmune/inflammatory disease programs powered by the QuEEN™ discovery platform.
Content highlights: Press releases covering preclinical breakthroughs, partnership announcements with pharmaceutical leaders, executive team updates, and financial disclosures. All materials are sourced directly from the company to ensure accuracy and timeliness.
Bookmark this page for streamlined tracking of Monte Rosa Therapeutics' advancements in targeted protein degradation therapies. Visit regularly to stay informed about developments in this cutting-edge area of precision medicine.
Monte Rosa Therapeutics (NASDAQ: GLUE) announced promising preclinical data on MRT-2359, a new orally bioavailable molecular glue degrader targeting MYC-driven tumors, including lung cancer. This data highlights MRT-2359's preferential anti-tumor activity in over 80 patient-derived xenografts, particularly those expressing high levels of N- and L-MYC. As the Phase 1/2 clinical trial (Identifier: NCT05546268) progresses, initial data from the Phase 1 arm is anticipated in late 2023. The trial focuses on evaluating safety, tolerability, and preliminary clinical activity in patients with solid tumors. The findings suggest that MRT-2359 effectively degrades GSPT1, disrupting protein synthesis and inhibiting MYC target gene expression. Monte Rosa aims to leverage its QuEEN™ platform to further enhance GSPT1 degradation and advance cancer treatment.
BOSTON, March 23, 2023 — Monte Rosa Therapeutics (NASDAQ: GLUE) announced the appointment of Jan Skvarka, Ph.D., MBA, to its Board of Directors. Dr. Skvarka brings over 30 years of experience in biopharmaceuticals, including leadership roles in clinical-stage companies. His tenure includes transforming Trillium Therapeutics from a $16 million market cap to a $2.3 billion acquisition by Pfizer within two years. Monte Rosa emphasizes its commitment to developing innovative molecular glue degrader medicines targeting serious diseases, leveraging its QuEEN™ platform. This appointment is viewed as a strategic move to advance its clinical and corporate objectives.
Monte Rosa Therapeutics (NASDAQ: GLUE) reported its fourth quarter and full year 2022 financial results, highlighting a net loss of $30.8 million in Q4 2022 and $108.5 million for the year. R&D expenses rose to $24.9 million for Q4 2022, driven by advancements in their MRT-2359 clinical trial for MYC-driven tumors, which received Fast Track designation from the FDA. The company ended 2022 with a cash balance of approximately $268 million, ensuring operational funding into 2025. Upcoming milestones include initial clinical data disclosure for MRT-2359 expected in late 2023 and nomination of development candidates from their various therapeutic programs.
BOSTON, Feb. 3, 2023 (GLOBE NEWSWIRE) -- Monte Rosa Therapeutics (NASDAQ: GLUE) is set to participate in several investor events, showcasing its advancements in molecular glue degrader (MGD) therapies. Key events include:
- Guggenheim Oncology Conference on February 9, 2023, at 2:45 p.m. ET
- BMO Virtual Biopharma Spotlight on February 10, 2023, at 10:00 a.m. ET
- SVB Securities Global Biopharma Conference on February 14, 2023, at 11:20 a.m. ET
- Wells Fargo Targeted Protein Degradation Summit on February 21, 2023, at 3:00 p.m. ET
- Cowen’s 43rd Annual Health Care Conference on March 7, 2023, at 10:30 a.m. ET
Webcasts will be available on the company's investor site.
Monte Rosa Therapeutics (NASDAQ: GLUE) announced key milestones for 2023, including FDA's Fast Track designation for MRT-2359 aimed at treating previously treated, metastatic non-small cell lung cancer (NSCLC) expressing L-MYC or N-MYC. Initial data from the ongoing Phase 1/2 trial is expected in H2 2023, alongside the nomination of additional development candidates. The company will present updates at the 41st Annual J.P. Morgan Healthcare Conference on January 11, 2023.
BOSTON, Jan. 04, 2023 (GLOBE NEWSWIRE) -- Monte Rosa Therapeutics (NASDAQ: GLUE), a biotechnology company focused on novel molecular glue degrader (MGD)-based medicines, announced that CEO Markus Warmuth is set to present at the 41st Annual J.P. Morgan Healthcare Conference on January 11, 2023, at 11:15 a.m. PT. The presentation will be accessible via the company’s investor site, with an archived version available for 90 days.
Monte Rosa's innovative approach utilizes a proprietary platform called QuEEN™ to identify therapeutic protein targets for drug development.
Monte Rosa Therapeutics (GLUE) announced significant advancements in its clinical programs, including the initiation of patient dosing for MRT-2359, a GSPT1-directed molecular glue degrader targeting MYC-driven tumors. The company reported a net loss of $27.3 million for Q3 2022, up from $19.8 million in Q3 2021. R&D expenses rose to $21.3 million due to expanded activities in MRT-2359 and the QuEEN™ platform. As of September 30, 2022, Monte Rosa maintains a cash position of $277.4 million, expected to support operations until late 2024.
Monte Rosa Therapeutics (NASDAQ: GLUE) has initiated dosing for its Phase 1/2 clinical trial of MRT-2359, targeting MYC-driven solid tumors like lung cancer. This investigational drug is a selective molecular glue degrader aimed at disrupting protein synthesis in these tumors. The trial's primary focus will be on safety, tolerability, and preliminary anti-tumor activity, with a concentration on cancer types characterized by prevalent MYC expression. The Chief Medical Officer emphasized the significance of this milestone, motivated by strong preclinical data and a commitment to improving patient outcomes.
Monte Rosa Therapeutics (NASDAQ: GLUE), a biotechnology firm focused on developing innovative molecular glue degrader-based therapies, has announced its participation in several upcoming investor conferences. These include the Credit Suisse 31st Annual Healthcare Conference from November 7-10, the Jefferies 13th Annual London Healthcare Conference from November 15-17, and the Piper Sandler 34th Annual Healthcare Conference from November 29 to December 1. Archived webcasts will be available on the company's investor site.
Monte Rosa leverages its proprietary QuEEN™ platform for protein degradation in drug discovery.
Monte Rosa Therapeutics (NASDAQ: GLUE) announced new preclinical data for MRT-2359, a GSPT1-directed molecular glue degrader targeting MYC-driven cancers. This data will be presented at the 5th Annual Targeted Protein Degradation Summit on October 25-28 in Boston and the EORTC-NCI-AACR Symposium in Barcelona on October 26-28. CEO Markus Warmuth highlighted the drug's ability to degrade GSPT1, enhancing anti-tumor activity. The company will also showcase its AI and machine learning capabilities aimed at novel MGD design.
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