Welcome to our dedicated page for Gritstone bio news (Ticker: GRTS), a resource for investors and traders seeking the latest updates and insights on Gritstone bio stock.
Our selection of high-quality news articles is accompanied by an expert summary from Rhea-AI, detailing the impact and sentiment surrounding the news at the time of release, providing a deeper understanding of how each news could potentially affect Gritstone bio's stock performance. The page also features a concise end-of-day stock performance summary, highlighting the actual market reaction to each news event. The list of tags makes it easy to classify and navigate through different types of news, whether you're interested in earnings reports, stock offerings, stock splits, clinical trials, fda approvals, dividends or buybacks.
Designed with both novice traders and seasoned investors in mind, our page aims to simplify the complex world of stock market news. By combining real-time updates, Rhea-AI's analytical insights, and historical stock performance data, we provide a holistic view of Gritstone bio's position in the market.
Gritstone bio, a clinical-stage biotechnology company (Nasdaq: GRTS), announced participation in two investor conferences. The 5th Annual Evercore ISI HealthCONx Conference is scheduled for November 29, 2022, featuring CEO Andrew Allen in a virtual fireside chat. The 34th Annual Piper Sandler Healthcare Conference will take place on December 1, 2022, with CFO Celia Economides and CBO Matthew J. Hawryluk presenting in New York. Live webcasts will be available for both events, and archived replays will be accessible for 30 days afterwards.
Gritstone bio, Inc. (Nasdaq: GRTS) announced updated overall survival (OS) results from its Phase 1/2 study of GRANITE, an individualized vaccine-based immunotherapy for metastatic microsatellite stable colorectal cancer (MSS-CRC). Patients with a molecular response have a median OS exceeding 22 months compared to 7.8 months for those without. This data highlights a significant survival advantage for patients not traditionally expected to benefit from immunotherapy. The ongoing randomized Phase 2/3 GRANITE study is expected to yield preliminary data in 4Q2023.
Gritstone bio, Inc. (NASDAQ: GRTS) reported encouraging developments in its clinical trials, showcasing the potential of self-amplifying mRNA (samRNA) vaccines against infectious diseases and cancer. Initial Phase 2 data from the KRAS-directed SLATE program indicated a molecular response rate of 40% in advanced lung cancer, comparable to prior results in colorectal cancer. The ongoing GRANITE study aims to establish strong data by 4Q2023. Financially, cash reserves totaled $151.8 million as of September 30, 2022, but R&D expenses increased to $26.4 million, suggesting ongoing investment in trials.
Gritstone bio, Inc. (Nasdaq: GRTS) announced a PIPE financing deal to sell 6,637,165 shares at $2.26 each and 13,274,923 pre-funded warrants at $2.2599, expected to generate approximately $45 million. The transaction, led by Redmile Group, is slated to close on October 27, 2022. Proceeds will support ongoing clinical development in oncology and infectious diseases. The securities are unregistered and require a registration statement with the SEC for resale. Gritstone aims to create potent vaccines leveraging innovative vectors for treating viral diseases and solid tumors.
Gritstone bio (GRTS) announced promising Phase 1 results from its CORAL-BOOST and CORAL-CEPI trials, showcasing strong immune responses from its self-amplifying mRNA (samRNA) vaccine candidates against SARS-CoV-2. Key findings include:
- High neutralizing antibody and T cell responses at 6 months post-vaccination
- Good tolerability across all dose levels tested
- Immunogenicity in vaccine-naïve subjects
These results further validate Gritstone's samRNA platform, emphasizing its potential in addressing unmet needs in infectious disease vaccination.
Gritstone bio, Inc. (Nasdaq: GRTS) has announced a webinar on October 25, 2022, to present data from its CORAL program, evaluating samRNA vaccine candidates against SARS-CoV-2. The Phase 1 trials, CORAL-BOOST and CORAL-CEPI, will feature presentations by prominent researchers, including Professor Andrew Ustianowski and Professor Shabir Madhi. Larry Corey, a leading expert in vaccine development, will discuss the broader applications of samRNA vaccines. Attendees can register for the event online and access a replay for 30 days post-event.
Gritstone bio (Nasdaq: GRTS) announced on October 17, 2022, that its Board of Directors granted seven employees stock options to purchase a total of 35,100 shares at an exercise price of $2.24 per share. This price reflects the closing stock price on the grant date, October 11, 2022. The stock options will vest over four years, with 25% vesting on the first anniversary of the hire date and the remainder vesting monthly thereafter. This initiative aligns with Nasdaq rules as an inducement for new hires.
On September 20, 2022, Gritstone bio, Inc. (Nasdaq: GRTS) announced that its Board of Directors granted nonqualified stock options for 12,400 shares to three new employees at an exercise price of $3.59, equal to the stock's closing price on September 9, 2022. These options will vest over four years to incentivize employee retention, with 25% vesting after the first year and the remainder vesting monthly. The grant aligns with Nasdaq Listing Rule 5635(c)(4) and is part of Gritstone's 2021 Employment Inducement Incentive Award Plan.
Gritstone bio (Nasdaq: GRTS) presented promising early results from its SLATE vaccine program at the 2022 ESMO Congress. The SLATE-KRAS vaccine demonstrated a 39% molecular response rate in patients with late-line microsatellite-stable colorectal cancer and non-small cell lung cancer. Notably, a correlation was observed between molecular response and overall survival (OS), with NSCLC patients showing a median OS of 9.6 months. The results indicate potential for earlier treatment lines in advanced cancer therapies, supported by favorable safety profiles and robust immune responses.
Gritstone bio, a clinical-stage biotechnology company, announced its participation in significant upcoming medical conferences. At the 2022 Wells Fargo Healthcare Conference in Boston, the company will present on September 8, 2022, at 1:20 PM EDT, featuring CFO Celia Economides and CBO Matthew J. Hawryluk. Additionally, Gritstone will engage in a fireside chat at the H.C. Wainwright 24th Annual Global Investment Conference on September 13, 2022, at 3:30 PM EDT with CEO Andrew Allen. Both events will be available via webcast on their website.