Welcome to our dedicated page for Hookipa Pharma news (Ticker: HOOK), a resource for investors and traders seeking the latest updates and insights on Hookipa Pharma stock.
HOOKIPA Pharma Inc. (HOOK) has described itself as a clinical-stage biopharmaceutical company developing next generation immunotherapeutics based on a proprietary arenavirus platform. Its news flow has highlighted programs in oncology and serious infectious diseases, including product candidates targeting HPV16-positive cancers, KRAS mutated cancers, and viral infections such as hepatitis B virus (HBV) and human immunodeficiency virus-1 (HIV-1).
Company press releases provide detailed updates on its collaboration and license agreement with Gilead Sciences, Inc. For example, HOOKIPA has reported on the HB-400 program in clinical development for HBV and the HB-500 program, a next-generation therapeutic vaccine being evaluated as a potential component of a curative regimen for HIV. News items have described clinical milestones such as enrollment completion in a Phase 1b trial of HB-500, including trial design elements and the intended role of HB-500 in a combination strategy for a potential functional cure of HIV.
HOOKIPA’s news coverage has also included significant corporate and strategic developments. In early 2025, the company issued multiple announcements related to a potential all-share combination with Poolbeg Pharma plc and associated U.K. Takeover Code disclosure requirements, followed by a Rule 2.8 statement that it did not intend to make an offer under Rule 2.7 of the Code. Subsequent releases detailed an asset purchase agreement with Gilead for HOOKIPA’s HB-400 program assets and certain HB-500 assets, and explained how this transaction related to the company’s long-term prospects and strategies.
Later announcements document HOOKIPA’s intention to voluntarily delist its common stock from the Nasdaq Capital Market, deregister its common stock under the Securities Exchange Act of 1934, and seek stockholder approval for dissolution and liquidation. Investors using this news page can review the sequence of clinical updates, collaboration news, U.K. takeover-related disclosures, and corporate actions such as the asset sale to Gilead, the special meeting of stockholders, and the steps toward delisting and deregistration. This provides a consolidated view of both scientific progress and material corporate events affecting HOOKIPA and the HOOK symbol.
HOOKIPA Pharma Inc. (NASDAQ: HOOK) announced it will release its third quarter financial results on November 10, 2021, before market opening. Notably, the company is focusing on developing a new class of immunotherapeutics based on its proprietary arenavirus platform, which activates the immune system against diseases. HOOKIPA is advancing its lead oncology products, HB-201 and HB-202, in clinical trials targeting HPV-related cancers, alongside a CMV vaccine candidate, HB-101. The company also collaborates with Gilead Sciences to research HIV and Hepatitis B treatments.
HOOKIPA Pharma has published a comprehensive review in Frontiers in Oncology, emphasizing the potential of its arenavirus platform as a novel immunotherapy for cancer. The review highlights pre-clinical and clinical data demonstrating effective tumor-specific CD8+ T cell responses following treatment with arenaviral immunotherapies like HB-200, particularly for patients with advanced HPV16+ cancer. HOOKIPA plans to advance HB-200 to Phase 2 trials and explore treatments for other cancers. Initial clinical data show promising efficacy, offering hope for improved cancer treatments.
HOOKIPA Pharma (NASDAQ: HOOK) announces a clinical collaboration with Merck to assess HB-200 with KEYTRUDA as a first-line treatment for advanced head and neck squamous cell carcinoma. This initiative follows promising results from the ongoing Phase 1/2 trial, where HB-201 showed an 18% overall response rate and a median progression-free survival of 3.45 months. Planned Phase 2 trials are set for 2022, indicating HOOKIPA's commitment to advancing its immunotherapeutic pipeline targeting HPV16-positive cancers.
HOOKIPA Pharma, listed on NASDAQ as HOOK, announced participation in several upcoming virtual investor conferences. Key events include the Morgan Stanley 19th Annual Global Healthcare Conference on September 9-10 and 13-15, featuring a fireside chat on September 10 at 8:45 AM ET. The H.C. Wainwright 23rd Annual Global Investment Conference is scheduled for September 13-15 with a presentation on September 13 at 7:00 AM ET. Additionally, HOOKIPA will present at the 2021 Cantor Virtual Global Healthcare Conference on September 28 from 8:00-8:30 AM ET. Webcasts will be available on their website.
HOOKIPA Pharma reported its Q2 2021 financial results, highlighting progress in its arenaviral immunotherapy programs. HB-200 for HPV16+ cancers showed promising Phase 1 data, with activated CD8+ T cells reaching up to 40% of the T cell pool. Revenue declined to $5.4 million from $6.7 million year-over-year, attributed to a lack of milestone payments from Gilead. The net loss increased to $17.2 million, up from $7.1 million in Q2 2020. Cash reserves decreased to $102.9 million, down from $143.2 million as of the end of 2020, reflecting increased R&D costs.
HOOKIPA Pharma has published promising pre-clinical data on its arenaviral-based immunotherapeutic targeting melanoma in Nature Communications. A single intra-tumoral injection resulted in tumor regression in all tested mice, achieving tumor cures in approximately 60%. The findings demonstrate the ability to modulate the tumor microenvironment and induce significant T cell responses. HOOKIPA’s ongoing Phase 1/2 trials with their HPV programs further explore this novel therapeutic platform, showcasing potential in cancer treatment and addressing unmet medical needs.
HOOKIPA Pharma Inc. (NASDAQ: HOOK) announced it will release its second quarter 2021 financial results on August 12, 2021, before market opening. The company focuses on developing novel immunotherapeutics using its proprietary arenavirus platform, with ongoing clinical trials for HPV 16-positive cancers and Cytomegalovirus. HOOKIPA aims to mobilize T cells and antibodies to combat serious diseases, with additional preclinical research in prostate cancer, HIV, and Hepatitis B in collaboration with Gilead Sciences.
HOOKIPA Pharma Inc. (NASDAQ: HOOK) announced participation in upcoming virtual investor conferences, including the SVB Leerink CybeRx Series on June 21-22 and the JMP Securities Life Sciences Conference on June 16-17, featuring a fireside chat on June 17 at 10:00am ET. The live webcast will be available on HOOKIPA's website, with an archived replay for 30 days. HOOKIPA focuses on developing immunotherapies using its proprietary arenavirus platform, targeting oncology and infectious diseases, with ongoing clinical trials for Human Papilloma Virus and Cytomegalovirus.
HOOKIPA Pharma reported positive Phase 1 data for HB-200, a novel arenaviral therapeutic targeting HPV16+ cancers, at the 2021 ASCO Annual Meeting. The therapy demonstrated an average of 6% to 40% tumor-specific CD8+ T cell responses, supporting its potential efficacy. HB-201 monotherapy achieved an 18% overall response rate and a median progression-free survival of 3.45 months in heavily pretreated patients. The findings suggest that HOOKIPA's arenaviral platform could facilitate new cancer immunotherapy options. Further studies are planned for 2022.
HOOKIPA Pharma announced that the first data from their Phase 1 study on HB-201/HB-202, an arenaviral therapeutic for HPV16+ cancers, will be presented at the ASCO Annual Meeting from June 4-8, 2021. This includes safety, tolerability, and preliminary anti-tumor activity from 40 patients. The presentation highlights the potential of HOOKIPA's novel immunotherapeutics to enhance cancer treatment. Following the presentation, an investor event will provide insights into the trial's findings and HOOKIPA's future plans.