Hoth Therapeutics Inc Stock Price, News & Analysis

Hoth Therapeutics (NASDAQ: HOTH) has announced the initiation of its first human clinical trial for topical BioLexa, targeting mild to moderate atopic dermatitis (eczema). This milestone addresses a significant unmet need for enhanced therapeutic solutions for eczema patients. The clinical trial is being conducted in Australia, with updates available on Hoth's website and ClinicalTrials.gov. CEO Robb Knie expressed enthusiasm for this advancement, highlighting its potential to improve patient quality of life.

Hoth Therapeutics, Inc. (NASDAQ: HOTH) announced promising results for its novel anti-cancer therapeutic targeting mast cell neoplasms, demonstrating significant tumor reduction and apoptosis in humanized models. The mRNA frame shifting therapy was well-tolerated with no toxicity observed. Hoth aims to accelerate clinical trial initiation based on these findings, which could represent a major advancement in treating aggressive mast cell-derived cancers. The company emphasizes its commitment to research and development for unmet medical needs.

Hoth Therapeutics (NASDAQ: HOTH) has finalized the formulation of HT-001, aimed at alleviating cutaneous toxicities in cancer patients undergoing EGFR inhibitor therapy. This development allows the company to initiate IND-enabling toxicology studies, crucial for the upcoming Phase 2a clinical trial, pending IND approval. The formulation, created with input from top scientific advisors, has shown promising efficacy in preliminary tests. Hoth now focuses on completing necessary regulatory studies for HT-001.

Hoth Therapeutics, Inc. (NASDAQ: HOTH) has partnered with Worldwide Clinical Trials for a Phase 2a dose-ranging clinical trial of HT-001. This trial aims to assess the efficacy and safety of HT-001 in treating cutaneous toxicities in cancer patients undergoing EGFR inhibitor therapy. The trial is a critical step toward an Investigational New Drug (IND) submission to the FDA, leveraging Worldwide's expertise in clinical studies. Hoth's focus is on addressing significant unmet medical needs associated with cancer treatment.

Hoth Therapeutics, Inc. (Nasdaq: HOTH) announced that the Brazilian Patent Office granted a notice of allowance for a patent application concerning a method to inhibit biofilm formation, issued on March 31, 2021. This new patent, noted by CEO Robb Knie, is part of the company's strategy to broaden its intellectual property portfolio in underserved global markets. The method, discovered by University of Cincinnati researchers, utilizes a zinc chelator to prevent biofilm creation by bacteria such as Staphylococcus epidermidis and Staphylococcus aureus.

Hoth Therapeutics, Inc. (NASDAQ: HOTH) announced positive in vitro results for its lead peptide candidate HT-002, aimed at treating COVID-19. The study demonstrated that HT-002 inhibited 50% of the cytopathic effect of SARS-CoV-2 at an effective concentration (EC₅₀) of 61.7 µM, with no observed cytotoxicity at concentrations up to 200 µM. Hoth plans further preclinical animal studies to explore the therapeutic potential and administration routes for HT-002, indicating a promising step in combating COVID-19.

Hoth Therapeutics, Inc. (NASDAQ: HOTH) announced that CEO Robb Knie will present at the Benzinga Biotech Small Cap Conference on March 24, 2021, at 12:10 p.m. ET. Following this, he will join a panel discussion titled 'Coming Together to Address Unmet Medical Needs' at 12:50 p.m. ET.

Interested attendees can register for the webcast by visiting Benzinga's event page. Hoth Therapeutics focuses on developing therapies for dermatological disorders and has recently advanced vaccine projects for COVID-19.

Hoth Therapeutics, Inc. (Nasdaq: HOTH), a clinical-stage biopharmaceutical company, announced that CEO Robb Knie will feature in an exclusive interview on The RedChip Money Report airing on Bloomberg Television on March 20 at 7 p.m. ET. The segment, reaching 73 million homes in the U.S. and 100 million in Europe, will cover Hoth's focus on targeted therapeutics for unmet medical needs, highlighting its pipeline including the BioLexa Platform and HT-001.

Hoth Therapeutics, Inc. (NASDAQ: HOTH) has entered into a research agreement with the University of Cincinnati Research Institute to conduct antimicrobial characterization studies for HT-006, a novel antibiotic targeting multi-drug resistant bacterial lung infections. The studies aim to expedite HT-006's development towards clinical use, addressing critical conditions like hospital-acquired pneumonia. Dr. Daniel Hassett will lead the research, which aligns with FDA guidelines for antibacterial therapies.