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HPE Introduces Industry-First 64 TB Memory Server for SAP Cloud ERP and Business-Critical Workloads

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in-memory database technical
An in-memory database stores and processes data primarily in a computer's main memory (RAM) instead of slower disk drives, so reads and writes happen much faster—like keeping frequently used files on your desktop rather than in a filing cabinet. Investors care because this speed enables real-time analytics, faster transactions and more responsive customer services, which can boost revenue, cut operational costs, and create a competitive technology edge that affects a company’s growth and risk profile.
sap hana technical
An in-memory data platform that stores and processes large amounts of business data very quickly, letting companies run real-time reporting and analytics instead of waiting hours or days. Think of it like replacing a slow filing cabinet with a high-speed search engine for a company’s records; for investors, it matters because faster, more accurate data can improve operational efficiency, decision-making, and competitive advantage, which can affect revenue and margins.
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DDR5 is the latest generation of high-speed volatile memory used as the short-term workspace for computers and servers, like a faster, larger desk where a processor keeps information it’s actively using. It matters to investors because upgrades to DDR5 drive demand across chip makers, computer builders and data-centre operators, affecting sales, pricing power and product cycles; companies that lead in DDR5 production or adoption can gain a competitive and financial edge.
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Post-quantum cryptography is a set of new methods for scrambling data so it stays secure even if powerful quantum computers exist; think of replacing today’s locks with designs that a future high‑speed lockpicker cannot open. For investors, it matters because companies must upgrade systems, meet regulations, and protect customer and trade data—creating costs, competitive advantages, or legal and reputational risks depending on how quickly and effectively they adopt these new security standards.
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HPE Compute Scale-up Server 3250 is the successor to industry-leading system available for RISE with SAP

In this article

  • HPE announced HPE Compute Scale-up Server 3250, a large, in-memory database server for critical and complex business workloads.
  • HPE recognized as a leader in the IDC MarketScape: Worldwide SAP HANA‑Certified Servers Appliances 2026 Vendor Assessment.

HOUSTON--(BUSINESS WIRE)-- HPE (NYSE: HPE) today announced the availability of HPE Compute Scale-up Server 3250, a purpose-built server for in-memory databases, engineered to deliver scalability, resilience, performance, and security for critical business transactional and analytics workloads. Powered by Intel Xeon 6 processors, HPE Compute Scale-up Server 3250 delivers the highest memory available as the first scale-up server validated by the SAP BW Edition HANA benchmark1 with at least 48 terabytes (TB) of memory.

“HPE Compute Scale-up Server 3250 raises the bar for business-critical infrastructure,” said Krista Satterthwaite, senior vice president and general manager, Compute at HPE. “Designed for complex business applications like enterprise resource planning and customer relationship management systems, this system helps customers in ways competitive offerings cannot – allowing them to run faster transactions, gain insights in real time, and support analytics without slowing down business. With simpler operations, always-on reliability, and chip-to-cloud security – we’re redefining what scale looks like for workloads with zero-tolerance downtime.”

The server scales modularly to meet the rising demands of real-time analytics and high-velocity transactions. Available from a minimum of four sockets, up to 16 – and supporting up to 64 TB of DDR5 memory – the server enables customers to run financial services applications, databases, and systems of record. A dedicated external node controller in HPE Compute Scale-up Server 3250 offers a performance boost that is 100 times2 faster than Ethernet used in scale-out deployments. This is HPE’s first scale-up server powered by Intel Xeon 6 processors and features a modular architecture well-suited for heavy compute and emerging agentic AI workloads.

“Our collaboration with HPE continues to blaze the trail for mission‑critical, in‑memory computing,” said Kevork Kechichian, executive vice president and general manager, Data Center Group at Intel. “The HPE Compute Scale‑Up Server 3250, powered by Intel Xeon 6 processors, brings together exceptional compute density, scalability, and reliability to help enterprises run their most critical data‑intensive workloads.”

Multi-layered security and resiliency

Built-in protection for HPE Compute Scale-up Server 3250 is available through HPE Integrated Lights Out (iLO) and spans every layer – from the chip to the cloud – as well as the entire lifecycle of the server. HPE iLO establishes a silicon root of trust through a dedicated security processor and validated firmware, which safeguards against future threats with post-quantum cryptography. Resiliency features of the HPE Compute Scale-up Server 3250 include advanced memory error detection and correction, as well as memory healing and deconfiguration. Additionally, the server is designed for fault-tolerant uptime, delivering the highest availability for critical business workloads.

HPE leadership for RISE with SAP-certified servers

HPE Compute Scale-up Server 3250 is the successor to the Intel-based HPE Scale-up Server 3200. HPE was recently named as a leader in the IDC MarketScape: Worldwide SAP HANA Certified Servers Appliances 2026 Vendor Assessment3. HPE’s long-standing collaboration with SAP and sustained engineering investment has positioned HPE as a leading provider of RISE with SAP-certified servers. HPE Compute Scale-up Server 3250 builds on that reputation with record-setting benchmark performance for large, in-memory configurations.

Availability

The HPE Compute Scale-up Server 3250 is available now.

This server can be acquired through HPE Financial Service’s 90/9 Advantage program that offers no payments for 90 days and an additional 9 months at one percent.

Additional Resources

About HPE

HPE (NYSE: HPE) is a leader in essential enterprise technology, bringing together the power of AI, cloud, and networking to help organizations achieve more. As pioneers of possibility, our innovation and expertise advance the way people live and work. We empower our customers across industries to optimize operational performance, transform data into foresight, and maximize their impact. Unlock your boldest ambitions with HPE. Discover more at www.hpe.com.

SAP and other SAP products and services mentioned herein as well as their respective logos are trademarks or registered trademarks of SAP SE in Germany and other countries. Please see https://www.sap.com/copyright for additional trademark information and notices.

©Intel, the Intel logo and other Intel marks are trademarks of Intel Corporation or its subsidiaries.

All other product and service names mentioned are the trademarks of their respective companies.

1 SAP Standard Application Benchmarks
2 Based on internal metrics, HPE Scale-up 3250 records ~100 nanoseconds of latency as compared to the average Ethernet connection that records 10,000 nanoseconds of latency
3 IDC MarketScape: Worldwide SAP HANA–Certified Server Appliances 2026 Vendor Assessment, (doc #US52979525, February 2026)

Media Contact:
Cristina Thai
cristina.thai@hpe.com

Source: Hewlett Packard Enterprise