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SeaStar Medical Holding (ICU) Stock News

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Welcome to our dedicated page for SeaStar Medical Holding news (Ticker: ICU), a resource for investors and traders seeking the latest updates and insights on SeaStar Medical Holding stock.

SeaStar Medical Holding Corporation develops and commercializes extracorporeal medical-device therapies for critically ill patients with organ failure driven by hyperinflammation. Its first commercial product, QUELIMMUNE (SCD-PED), is based on the company’s Selective Cytopheretic Device technology and is FDA approved for pediatric acute kidney injury associated with sepsis or a septic condition in patients requiring renal replacement therapy.

Recurring company updates cover QUELIMMUNE adoption by children’s hospitals, SAVE post-approval registry data, publications and conference presentations, and financial results. News also addresses clinical development of SCD therapy in adult acute kidney injury requiring continuous renal replacement therapy and in cardio-renal indications, as well as FDA Breakthrough Device and Humanitarian Device pathways for additional SCD uses.

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SeaStar Medical (NASDAQ: ICU) has undertaken several measures to regain compliance with Nasdaq's listing requirements after receiving a notification of non-compliance in June 2024. The company completed a $4.0 million public offering and secured a $15.0 million purchase agreement with Lincoln Park Capital.

The company has expanded its customer base to six facilities for QUELIMMUNE, its FDA-approved product for pediatric patients with multiple organ failure, which has shown to reduce mortality by approximately 50%. Additionally, SeaStar implemented cost-cutting measures and restructured approximately $1.2 million in employee compensation liabilities. The company believes these actions have helped it meet the $2.5 million stockholders' equity requirement for continued Nasdaq listing, pending formal confirmation.

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SeaStar Medical (NASDAQ: ICU) announced a two-part video series featuring their QUELIMMUNE therapy at Cincinnati Children's Hospital Medical Center. The first video, available June 24, 2025, features Dr. Stuart Goldstein and CMO Dr. Kevin Chung discussing QUELIMMUNE's potential to reduce destructive hyperinflammation in organ failure cases.

The second video, releasing June 26, 2025, showcases a patient testimonial from Kurt and his father, describing Kurt's rapid recovery from post-heart surgery complications using QUELIMMUNE therapy. Both videos will be accessible through SeaStar Medical's investor relations website.

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SeaStar Medical (NASDAQ: ICU) has announced a public offering to raise up to $8 million, with $4 million expected initially and potential additional $4 million through warrant exercises. The offering includes 6,153,847 shares of common stock priced at $0.65 per share, along with Series A warrants (5-year term) and Series B short-term warrants (18-month term), both with $0.65 exercise price. The offering, managed by H.C. Wainwright & Co. as exclusive placement agent, is expected to close around June 23, 2025. The company plans to use proceeds for general corporate purposes. The offering is made through a Form S-1 registration statement declared effective on June 20, 2025.
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SeaStar Medical (Nasdaq: ICU) and AREVA Research Institute announced a significant Department of Defense (DoD) grant award to study SeaStar's Selective Cytopheretic Device (SCD) therapy. The $2 million grant, selected from 160 submissions to the Military Burn Research Program, will fund a three-year study starting July 2025 to evaluate SCD therapy's effectiveness in reducing hyperinflammation in cases of severe burns, inhalation injury, and sepsis. The SCD therapy, used alongside continuous renal replacement therapy (CRRT), aims to neutralize hyperinflammation and support organ recovery. The research will be conducted at AREVA Institute in San Antonio, with operational support from The Geneva Foundation, potentially advancing treatment options for both military and civilian trauma patients.
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SeaStar Medical (NASDAQ: ICU) has secured CMS coverage for Medicare and Medicaid patients enrolled in the NEUTRALIZE-CRS clinical trial, marking its second CMS reimbursement award. The trial evaluates the company's Selective Cytopheretic Device (SCD) therapy in patients with cardiorenal syndrome awaiting LVAD implantation. This rare achievement, granted to less than 100 trials annually, follows their July 2024 CMS coverage for the NEUTRALIZE-AKI pivotal trial. The company is also advancing pre-commercialization efforts for SCD therapy in Acute Kidney Injury (AKI) patients, with the NEUTRALIZE-AKI trial currently 50% enrolled. Both the AKI and cardiorenal syndrome applications have received FDA Breakthrough Device Designation. The NEUTRALIZE-CRS trial, supported by a $3.6M NIH grant, aims to enroll 20 patients across five clinical sites.
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SeaStar Medical (NASDAQ: ICU) reported Q1 2025 financial results, highlighting a four-fold increase in QUELIMMUNE net product revenue to $293,000 compared to Q4 2024's $68,000. The company's NEUTRALIZE-AKI pivotal trial reached 50% enrollment, triggering an interim analysis expected in Q3 2025. SeaStar secured three new customers for QUELIMMUNE and received two new FDA Breakthrough Device Designations for SCD therapy in cardiac surgery patients. Financial results showed a net loss of $3.8 million ($0.44 per share), improved from $12.7 million loss in Q1 2024. R&D expenses increased to $2.4 million, while G&A expenses decreased to $1.7 million. The company reported cash and equivalents of $5.3 million, bolstered by a $6.0 million registered direct offering in January 2025.
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SeaStar Medical (NASDAQ: ICU) has reached the halfway point in its NEUTRALIZE-AKI pivotal clinical trial, enabling a prespecified interim analysis of its SCD therapy for treating adult patients with Acute Kidney Injury (AKI) requiring continuous renal replacement therapy. The trial's independent Data Safety Monitoring Review Board (DSMB) will analyze data from the first 100 of 200 planned patients, with findings expected in Q3 2025.

The interim analysis will evaluate safety and powering assumptions, remaining blinded to all parties except the DSMB. The therapy has received FDA Breakthrough Device Designation. The trial includes prestigious clinical sites such as Cleveland Clinic, Mayo Clinic, and Stanford Medical Center, with previous studies showing improved treatment outcomes compared to standard care.

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SeaStar Medical (Nasdaq: ICU) has announced it will release its first quarter 2025 financial results after market close on Wednesday, May 14, 2025. The company, which specializes in treatments for critically ill patients facing organ failure, will host a conference call and webcast at 4:30 p.m. ET / 2:30 p.m. MT on the same day to discuss the results and business progress.

Interested parties can access the call using Conference ID 2078693, with dial-in numbers 1 (800) 715-9871 for U.S. participants and 1 (646) 307-1963 for international callers. A replay will be available through May 20, 2025, at 1 (609) 800-9909.

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SeaStar Medical Holding Corporation (Nasdaq: ICU), a commercial-stage healthcare company specializing in treatments for critically ill patients with organ failure, has announced an upcoming CEO interview. Eric Schlorff, the company's CEO, will appear on the Benzinga All Access Show today, April 30, 2025, at approximately 10:50 am Eastern Time.

The live interview will be broadcast on YouTube, and viewers can access it through the provided link. For those unable to watch the live broadcast, a recording will be made available afterward on SeaStar Medical's website in the investor relations section, specifically on the Events and Presentations page.

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SeaStar Medical (Nasdaq: ICU) has received two new FDA Breakthrough Device Designations for its Selective Cytopheretic Device (SCD) therapy, targeting systemic inflammatory response in both adult and pediatric cardiac surgery patients. The designations aim to prevent post-operative complications in high-risk populations.

The potential market includes approximately 45,000 patients annually - 15% of 300,000 adult cardiac surgery patients and one-third of 40,000 pediatric congenital heart surgery patients. These new designations bring SeaStar's total to six, highlighting the critical need for effective hyperinflammation treatment.

The company is currently commercializing QUELIMMUNE for pediatric acute kidney injury treatment and conducting the NEUTRALIZE-AKI pivotal trial for adult patients. SeaStar's six Breakthrough Device Designations, granted between April 2022 and March 2025, cover treatments for Adult AKI, cardiac surgery inflammation, cardiorenal syndrome, ESRD, and hepatorenal syndrome.

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FAQ

What is the current stock price of SeaStar Medical Holding (ICU)?

The current stock price of SeaStar Medical Holding (ICU) is $4.2 as of May 14, 2026.

What is the market cap of SeaStar Medical Holding (ICU)?

The market cap of SeaStar Medical Holding (ICU) is approximately 18.4M.