Immunocore Holdings Plc Stock Price, News & Analysis

Immunocore (Nasdaq: IMCR) presented Phase 1 single‑ascending‑dose data for IMC-I109V at AASLD The Liver Meeting on November 7, 2025. The bispecific TCR candidate showed a manageable safety profile and pharmacodynamic activity consistent with its mechanism, including dose‑dependent reductions in HBsAg at doses ≥ 7 mcg, with HBsAg nadirs typically by day 8. Four participants met the predefined ≥ 0.2 log10 HBsAg reduction threshold. Treatment‑related adverse events were mostly transient; one Grade 2 cytokine release syndrome at 20 mcg resolved with treatment.

The company plans further evaluation in multiple‑dose regimens.

Immunocore (Nasdaq: IMCR) reported 3Q 2025 results and a business update on November 6, 2025. KIMMTRAK net product sales were $103.7M in the quarter (+29% YoY) and $295.5M year-to-date. Cash, cash equivalents and marketable securities were $892.4M as of September 30, 2025. The company is advancing multiple registrational trials: Phase 3 TEBE-AM (enrollment on track to complete 1H 2026) and Phase 3 PRISM-MEL-301 (brenetafusp 160 mcg selected by IDMC). R&D and SG&A increased QoQ, and GAAP net loss was ($0.2M) in 3Q 2025. Key pipeline areas include oncology (PRAME, IMC-R117C), infectious disease (HIV, HBV), and autoimmune programs.

Resolution Therapeutics has strengthened its leadership team with two key appointments: Lucy Singah as Chief Financial Officer and Daniel Kennedy as Chief Business Officer. The appointments follow the successful dosing of the first patient in the company's Phase I/II EMERALD study.

Lucy Singah brings over 20 years of corporate and strategic finance experience from companies including Echopoint Medical, GSK, and EY. Daniel Kennedy, with more than 20 years of business development experience, joins from Immunocore (NASDAQ: IMCR) and previously led deals at Achillion Pharmaceuticals, including its $930 million acquisition by Alexion.

The company will host an R&D Webinar on September 17, 2025, featuring clinical hepatologists to discuss its regenerative macrophage therapy (RMT) platform for inflammatory and fibrotic diseases.

Immunocore (NASDAQ: IMCR), a commercial-stage biotechnology company, has announced its participation in four major investor conferences in September 2025. The company will participate in the Cantor Global Healthcare Conference (Sept 5), H.C. Wainwright Global Investment Conference (Sept 8), Baird Global Healthcare Conference (Sept 9), and Morgan Stanley Global Healthcare Conference (Sept 10).

Immunocore specializes in developing novel TCR bispecific immunotherapies (ImmTAX) for cancer, autoimmune, and infectious diseases. Their flagship product, KIMMTRAK, is approved in multiple regions for treating HLA-A*02:01-positive adult patients with unresectable or metastatic uveal melanoma.

Immunocore (NASDAQ:IMCR) reported strong Q2 2025 financial results, with KIMMTRAK net revenues reaching $98.0 million, representing a 30% year-over-year growth. The company achieved significant market expansion with KIMMTRAK now approved in 39 countries and launched in 28 countries globally.

Key highlights include 15% growth in US sales and 71% growth in Europe and international regions. The company maintains a strong financial position with $883 million in cash and equivalents. R&D expenses increased to $69.0 million, reflecting investments in autoimmune programs and Phase 3 trials.

Clinical progress remains on track with the Phase 3 TEBE-AM trial expected to complete enrollment in 1H 2026, and dose selection for PRISM-MEL-301 Phase 3 trial anticipated in 2H 2025. The company reported a reduced net loss of $10.3 million compared to $11.6 million in the same period last year.

Immunocore Holdings plc (Nasdaq: IMCR), a commercial-stage biotechnology company, will release its second quarter 2025 financial results on Thursday, August 7, 2025, before US markets open. The company will host a conference call and webcast at 8:00 a.m. EDT to discuss results and provide business updates.

Immunocore specializes in developing novel TCR bispecific immunotherapies (ImmTAX) for cancer, autoimmune, and infectious diseases. Their lead product, KIMMTRAK, is approved in multiple regions for treating HLA-A*02:01-positive adult patients with unresectable or metastatic uveal melanoma.

Immunocore Holdings plc (Nasdaq: IMCR), a commercial-stage biotechnology company focused on developing immunomodulating medicines for cancer, infectious diseases, and autoimmune diseases, has announced its participation in the upcoming 2025 Jefferies Global Healthcare Conference. The company's management will engage in a fireside chat on Thursday, June 5, 2025, at 11:05 a.m. EDT. The presentation will be accessible through a live webcast on the 'Events & Presentations' section of Immunocore's website, with a replay available for a limited time after the event.

Immunocore (IMCR) reported strong Q1 2025 financial results, with KIMMTRAK net revenues reaching $93.9 million, up 33% year-over-year. The company achieved net income of $5.0 million compared to a $24.4 million loss in Q1 2024, with earnings per share of $0.10. KIMMTRAK is now approved in 39 countries and launched in 26 markets globally. The company maintains a strong financial position with $837 million in cash and equivalents. Key pipeline developments include progress in Phase 3 trials: TEBE-AM trial enrollment completion expected in 1H 2026, and dose selection for PRISM-MEL-301 trial anticipated in 2H 2025. The company also presented initial multiple ascending dose data for their HIV functional cure candidate at CROI 2025.

Immunocore (NASDAQ: IMCR) has presented initial data from the multiple ascending dose (MAD) portion of its Phase 1/2 STRIVE trial for IMC-M113V, a functional HIV cure candidate. The study included 16 HIV-positive participants across three dose cohorts (60 mcg, 120 mcg, and 300 mcg).

Key findings show that IMC-M113V was well-tolerated with no serious adverse events. The 300 mcg cohort showed promising results, with 2 out of 5 patients demonstrating viral control. Notably, these patients maintained viral loads around 200 c/mL at week 8, significantly better than the historical rate of 5%.

The trial revealed dose-dependent viral control after antiretroviral treatment interruption, with some patients showing reduced CD4+ T cell-associated HIV Gag RNA, indicating a reduction in active virus reservoir. Two patients remained off antiretroviral treatment for the entire 12-week interruption period, with one patient showing viral reduction to <50 c/mL at week 12 - an outcome typically seen in <1% of cases.