Immunocore Holdings Plc Stock Price, News & Analysis

Immunocore reported financial results for Q4 and the full year 2022, with KIMMTRAK generating net revenues of £42 million ($51 million) in Q4 and £117 million ($141 million) for the year. The therapy is approved in over 30 countries and has treated nearly 200 patients under an early access program. The company has a cash position of £401.6 million, providing a runway into 2026. R&D expenses rose to £89.2 million as the company advances various clinical trials, including new targets for PRAME and PIWIL1. Notable awards were received for KIMMTRAK, reflecting its clinical benefits.

Immunocore Holdings Plc (Nasdaq: IMCR) announces upcoming presentations at key investor conferences in March 2023, focusing on its pioneering T cell receptor (TCR) bispecific immunotherapies. The conferences include:

• Cowen 43rd Annual Health Care Conference on March 6 at 1:30 p.m. ET
• Oppenheimer 33rd Annual Healthcare Conference on March 14 at 8:00 a.m. ET
• Barclays Global Healthcare Conference on March 15 at 3:35 p.m. ET
• Jefferies Biotech on the Bay Summit on March 16, 2023

Live webcasts of the presentations will be available on Immunocore's website.

Immunocore (Nasdaq: IMCR) will report its 2022 earnings on March 1, 2023, before the US markets open. The company, known for its pioneering T cell receptor (TCR) bispecific immunotherapies, will host a live teleconference at 8:00 a.m. ET to discuss the financial results and provide updates. KIMMTRAK, Immunocore's leading oncology TCR therapy, is currently approved for treating HLA-A*02:01-positive adult patients with advanced uveal melanoma in several regions, including the US and Europe. Shareholders and interested parties can access the earnings call via the company’s website, with a replay available for 90 days.

Immunocore has announced initial Phase 1 results for IMC-M113V, a novel soluble TCR therapy aimed at treating HIV. The trial data, presented at the CROI conference, indicates that doses administered were well tolerated, with no severe adverse events reported. At the highest dose of 15 mcg, half of the participants exhibited significant T cell activation markers, maintaining suppressed plasma viral loads. The company is advancing to a multiple ascending dose (MAD) phase to identify optimal dosing schedules for potential ‘functional cure’ outcomes. Immunocore's approach targets CD4+ cells harboring HIV, a promising step toward alleviating lifelong antiretroviral dependence.

Immunocore Holdings Plc (Nasdaq: IMCR) announced presentations at key investor conferences in February 2023. The conferences include the Guggenheim Oncology Conference on February 8, SVB Securities Global Biopharma Conference on February 16, and Citi's 2023 Virtual Oncology Leadership Summit on February 22. Each session will feature a fireside chat and will be webcast live. Immunocore specializes in developing T cell receptor (TCR) bispecific immunotherapies for various diseases, including cancer and autoimmune conditions. The company’s flagship therapy, KIMMTRAK, is approved for treating certain types of uveal melanoma.

The report titled "Global TCR Therapy Market, 2022-2035" outlines significant growth prospects in TCR-based therapies, with an annual growth rate of 51% expected over the next decade. This emerging class of adoptive therapy targets specific tumor markers using genetically modified T-cells, showing efficacy primarily in hematological and solid tumors. The FDA's approval of Kimmtrak for treating metastatic uveal melanoma in January 2022 marks a milestone in the market. The market is projected to be driven by nasopharyngeal carcinoma, multiple myeloma, and head and neck carcinoma, with over 90% of therapy candidates being autologous.

The global cancer immunotherapy market is projected to reach USD 196.45 billion by 2030, growing at a CAGR of 7.2%, according to a report by Grand View Research. The increasing use of immunotherapy due to its targeted approach and heightened regulatory approvals for novel treatments are key growth factors. Monoclonal antibodies lead market share, while oncolytic viral therapies and vaccines are expected to grow rapidly. Lung cancer treatment is currently dominant, with a growing focus on prostate cancer. Notably, the Asia Pacific region is forecasted to experience the fastest growth driven by healthcare advancements and unmet medical needs.

Immunocore Holdings plc announced strategic priorities for 2023-2024, emphasizing pipeline expansion and the continued global rollout of KIMMTRAK (tebentafusp-tebn). The drug has been approved in over 30 countries with preliminary unaudited net sales of approximately $50 million for Q4 2022 and $140 million for the full year. Key priorities include the enrollment in IMC-F106C trials and the introduction of new ImmTAC candidates targeting PRAME and PIWIL1. The company aims to solidify KIMMTRAK as the first-line treatment for metastatic uveal melanoma.

Immunocore Holdings (Nasdaq: IMCR) announced its participation in the 41st Annual J.P. Morgan Healthcare Conference on January 11, 2023, at 9:00 a.m. PST. The company's management will engage in a fireside chat, which will be webcast live, and available on Immunocore's website. Immunocore specializes in pioneering T cell receptor bispecific immunotherapies, notably its approved oncology therapeutic, KIMMTRAK, intended for treating unresectable or metastatic uveal melanoma. The company is progressing on multiple clinical and pre-clinical programs across various disease areas.