Immutep Stock Price, News & Analysis

Immutep Limited (NASDAQ: IMMP) announced promising interim results from the Phase II TACTI-002 trial for patients with 2nd line PD-X refractory non-small cell lung cancer (NSCLC). Key findings include a median overall survival of 9.7 months and a 36.5% survival rate at 18 months for patients receiving efti combined with pembrolizumab. The study, which involves 36 patients, shows favorable safety and tolerability compared to traditional chemotherapy. These results support the potential of efti as a viable treatment option for advanced NSCLC patients.

Immutep Limited (NASDAQ: IMMP) announced significant progress in its clinical trials for cancer therapies. The Phase II TACTI-002 trial demonstrated a 38.6% Overall Response Rate for efti in 1st line non-small cell lung cancer patients. Additionally, biomarker analysis from the Phase IIb AIPAC trial confirmed that efti activates the immune system, correlating with improved survival rates. The company remains well-funded, with approximately $80 million in cash, ensuring operational stability into early 2024. Four notable oncologists have joined the Clinical Advisory Board to enhance strategic direction.

Immutep Limited (ASX: IMM; NASDAQ: IMMP) has announced the grant of a new patent by the Japanese Patent Office for its pre-clinical candidate IMP761, targeting autoimmune diseases. The patent is valid until September 1, 2036, and follows a similar grant in Europe. CEO Marc Voigt highlighted the importance of protecting IMP761, which operates as a LAG-3 agonist, aiming to treat the underlying causes of autoimmune diseases. The company is collaborating with Northway Biotech for GMP compliant manufacturing ahead of clinical testing.

Immutep Limited (ASX: IMM; NASDAQ: IMMP) announced new data from the Phase II TACTI-002 trial focusing on non-small cell lung cancer (NSCLC) patients. This data will be presented at the IASLC 2022 World Conference on Lung Cancer in Vienna from August 6-9, 2022. The poster's abstract will be available on July 8, 2022. The TACTI-002 trial evaluates the combination of eftilagimod alpha and pembrolizumab in patients with second line PD-1/PD-L1 refractory metastatic NSCLC. Immutep is dedicated to developing innovative immunotherapy treatments for cancer and autoimmune diseases.

Immutep has announced positive results from the Phase II TACTI-002 trial, evaluating the combination of eftilagimod alpha (efti) and pembrolizumab (KEYTRUDA) in 1^st line non-small cell lung cancer (NSCLC) patients. The study met its primary objective with an Overall Response Rate (ORR) of 38.6% across 114 patients, exceeding historical anti-PD-1 monotherapy results. Notably, responses were observed in patients with low or negative PD-L1 expression. The treatment was reported safe and well-tolerated, supporting further late-stage development.

Immutep Limited (ASX: IMM; NASDAQ: IMMP) will host a global webcast on June 7, 2022, to discuss new data from its Phase II TACTI-002 trial for non-small cell lung cancer (NSCLC). This data will be presented at the ASCO 2022 Annual Meeting on June 3, 2022. Immutep's CEO Marc Voigt and other executives will speak during the webcast. Their lead product, eftilagimod alpha, is a LAG-3 related immunotherapy treatment for cancer and autoimmune diseases. The company aims to enhance treatment options for patients and value for shareholders.

Immutep Limited (ASX: IMM; NASDAQ: IMMP) has released interim data from its Phase II TACTI-002 trial, demonstrating positive antitumor activity of eftilagimod alpha in first-line non-small cell lung cancer (NSCLC) patients. The Overall Response Rate (ORR) improved to 37.3% among the 75 patients, up from 36.1% reported at ASCO 2021, with a Disease Control Rate (DCR) of 73.3%. Efti combined with pembrolizumab remains safe and well-tolerated. Data from all 114 patients will be presented on June 3, 2022, along with updates on the ongoing Phase IIb TACTI-003 trial.

Immutep Limited (NASDAQ: IMMP) announced its participation in several upcoming investor conferences, showcasing its advancements in immunotherapy for cancer and autoimmune diseases. Key events include:

• Wilsons Rapid Insights: 26 May 2022, in-person, with Marc Voigt and Deanne Miller presenting.
• Jefferies Australia MedTech/Biotech Summit: 26-27 May 2022, virtual presentation by Marc Voigt.
• Jefferies Global Healthcare Conference: 8-10 June 2022, in-person, with a live webcast on 10 June.

Immutep is at the forefront of developing LAG-3 related immunotherapy solutions.

Immutep announced the appointment of four new members to its Clinical Advisory Board (CAB), enhancing its strategic resources for advancing LAG-3-related immunotherapy treatments. The new members, experts in oncology and immunotherapy, will focus on late-stage development programs for the lead product, eftilagimod alpha. This move aims to strengthen Immutep's position as a leader in innovative cancer therapies, especially targeting metastatic breast and non-small cell lung carcinomas.