Welcome to our dedicated page for Immutep news (Ticker: IMMP), a resource for investors and traders seeking the latest updates and insights on Immutep stock.
Immutep Limited reports clinical and corporate developments as a clinical-stage biotechnology company developing Lymphocyte Activation Gene-3 (LAG-3) related immunotherapies for cancer and autoimmune diseases. Its updates center on eftilagimod alfa (efti), a LAG-3 immunotherapy evaluated in cancer studies, and IMP761, a LAG-3 agonist antibody for autoimmune disease.
Recurring company news covers trial results and changes across programs such as TACTI-004, INSIGHT-003 and EFTISARC-NEO, FDA orphan drug designation for efti in soft tissue sarcoma, scientific-conference abstracts, development and commercialization collaborations, quarterly activities reports, cash runway commentary and Nasdaq ADR listing compliance matters.
Immutep Limited (NASDAQ: IMMP) announced encouraging interim results from its Phase II TACTI-002 trial for 2nd line metastatic non-small cell lung carcinoma (NSCLC). Key findings include a Disease Control Rate (DCR) of 36.1% and a 73% overall survival rate at six months. 73.7% of patients experienced tumor shrinkage or deceleration, with 5.6% achieving durable partial responses. The treatment, combining eftilagimod alpha (efti) with pembrolizumab, continues to demonstrate safety and tolerability. More mature data is anticipated later this year.
Immutep Limited (ASX: IMM; NASDAQ: IMMP) announced promising interim results from Part B of the TACTI-002 trial, focusing on 2nd line NSCLC patients. The combination of eftilagimod and pembrolizumab demonstrated a 6% overall response rate and a 36% disease control rate among 36 patients. The treatment was found to be safe and well-tolerated, with ongoing data on overall survival and tumour growth kinetics to be presented at the European Lung Cancer Congress (ELCC) 2022.
Immutep Limited (ASX: IMM; NASDAQ: IMMP) announced new biomarker data from its Phase IIb AIPAC trial at the ESMO Breast Cancer Congress 2022, occurring from May 3-5, 2022, in Berlin, Germany. The trial assessed eftilagimod alpha combined with paclitaxel in 227 HER2-negative/HR positive metastatic breast cancer patients. New multivariate analysis results will be presented by Prof. Dr. Frederik Marmé on May 4, 2022. For further details, visit Immutep's website.
Immutep Limited (ASX: IMM; NASDAQ: IMMP) announced the grant of patent no. 7030750 by the Japanese Patent Office for antibody molecules targeting LAG-3, crucial for cancer treatment. This divisional patent follows a previous grant in 2019, with corresponding patents in territories like Australia, China, Europe, and the U.S. The patent, co-owned with Novartis AG, will expire on March 13, 2035. LAG525, a humanized form of IMP701, is being evaluated by Novartis in clinical trials for cancer, with Immutep set to receive milestone payments and royalties upon commercialization.
Immutep Limited (NASDAQ: IMMP) announced that it received positive feedback from the FDA regarding its lead product, eftilagimod alpha (efti), for the treatment of metastatic breast cancer (MBC). The FDA supports advancing efti into a new registrational trial, AIPAC-003, which will optimize patient selection based on completed phase IIb AIPAC trial data. This follows earlier feedback from the EMA. The upcoming trial aims to solidify the best design for efti, which targets patients who are unlikely to benefit from conventional therapies.
Immutep Limited (ASX: IMM; NASDAQ: IMMP) announced its participation in notable investor conferences, including the 42nd Annual Cowen Health Care Conference from March 7-9, 2022, where CEO Marc Voigt will present on March 8 at 9:10 am EST. A live webcast will be available. Additionally, Immutep will engage in a fireside chat at the Maxim Growth Conference from March 28-30, 2022, set for March 28 at 11:00 am EDT. Immutep focuses on developing LAG-3 related immunotherapies for cancer and autoimmune diseases.
Immutep (ASX: IMM; NASDAQ: IMMP) will present new data from its phase II TACTI-002 trial at the European Lung Cancer Congress (ELCC) 2022 in Prague and virtually from March 30 to April 2, 2022. The study evaluates eftilagimod alpha combined with KEYTRUDA® in patients with PD-L1 unselected, refractory metastatic non-small cell lung cancer (NSCLC). The poster presentation is scheduled for April 1, 2022, at 12:00 noon CEST by Dr. Matthew G. Krebs. Immutep aims to advance its LAG-3 related immunotherapeutic developments.
Immutep Limited (NASDAQ: IMMP) announced the grant of a new patent by the Australian Patent Office for its lead immunotherapy candidate, eftilagimod alpha (efti or IMP321). This patent, protecting combined preparations for treating cancer, follows similar grants in Europe, the U.S., and China. The claims cover specific combinations of efti with various anti-PD-1/PD-L1 antibodies, expiring on January 8, 2036. CEO Marc Voigt highlighted the importance of this patent in the context of significant interest in the LAG-3 mechanism following Phase III clinical data publication.
Immutep (ASX: IMM; NASDAQ: IMMP) has announced participation in two key investor conferences in February 2022. CEO Marc Voigt will present at the 11th Annual SVB Leerink Global Healthcare Conference from February 14-18, followed by a Q&A session on February 18 at 3:40 PM ET. Additionally, Immutep will be at the 2022 BIO CEO & Investor Conference from February 14-17. The company's focus is on developing immunotherapy treatments for cancer and autoimmune diseases, primarily through its lead candidate, eftilagimod alpha.
Immutep Limited (NASDAQ: IMMP) reported significant advancements in its clinical trials for cancer therapies, particularly its lead product, eftilagimod alpha (efti). The Phase IIb AIPAC trial demonstrated a notable overall survival benefit, with a +7.5 month increase for patients under 65 and +19.6 months for those with low monocytes. The company is preparing for a Phase III trial and has initiated patient recruitment for TACTI-003. Financially, cash on hand is $99.66 million, projected to fund operations until December 2023.