Immunome Inc Stock Price, News & Analysis

Immunome (NASDAQ: IMNM) announced positive in vitro results for its antibody cocktail against the SARS-CoV-2 Omicron variant, demonstrating comparable potency to GSK/Vir's sotrovimab. The tests conducted at Boston University and Washington University confirmed that the combination of IMM20253 and IMM20184 neutralized Omicron with an IC50 of 27 nM. The cocktail employs a novel mechanism that enhances viral resistance, targeting the spike protein's ACE2 binding site. Moving forward, Immunome plans to advance its program into Phase 1b trials, supported by funding from the U.S. Department of Defense.

Immunome has received a clinical hold letter from the FDA regarding its IND submission for IMM-BCP-01, a three-antibody cocktail for COVID-19. The FDA has requested additional information about the cocktail's preparation and administration at clinical sites. Immunome intends to provide this information promptly and is still on track to report top-line clinical data for IMM-BCP-01 within the first half of 2022. Additionally, external laboratory tests for the cocktail's efficacy against the Omicron variant are expected this month.

Immunome, Inc. (Nasdaq: IMNM) will participate in a fireside chat hosted by Cantor Fitzgerald's Brian Cheng on December 8, 2021, at 1:00 p.m. ET, aimed at institutional clients. The event will be accessible via webcast, with a replay available on Immunome's website for 30 days following the live presentation.

Immunome utilizes its proprietary human memory B cell platform to develop innovative antibody therapeutics focusing on oncology and infectious diseases, including COVID-19.

Immunome expects its antibody cocktail, IMM-BCP-01, to be effective against the Omicron variant of SARS-CoV-2. The company is performing laboratory testing to confirm this, with results anticipated in January 2022. IMM-BCP-01 targets three distinct epitopes, enhancing its potential resilience against mutations. The cocktail approach aims to improve viral neutralization, as demonstrated in preclinical tests against other variants. Immunome is advancing IMM-BCP-01 towards clinical trials, pending regulatory approval.

Immunome, Inc. (NASDAQ: IMNM) has submitted an Investigational New Drug (IND) application to the U.S. FDA for IMM-BCP-01, a novel three-antibody cocktail targeting SARS-CoV-2. This submission marks a significant milestone for Immunome as they prepare to conduct clinical studies. Preclinical testing shows that IMM-BCP-01 effectively reduces viral load and encompasses broad coverage against various COVID-19 variants. The project is funded by the U.S. Department of Defense, emphasizing its public health importance as COVID-19 continues to pose a threat.

Immunome, Inc. (Nasdaq: IMNM) made progress in its antibody development, notably with IMM-BCP-01, targeting SARS-CoV-2 variants Lambda and Delta Plus. The company plans to submit an IND for IMM-BCP-01 this quarter, alongside anticipated topline data in H1 2022. Financially, for Q3 2021, R&D expenses reached $4.5M, while G&A expenses were $3.2M, leading to a net loss of $7.7M. As of September 30, 2021, cash reserves stood at $56.3M, indicating sufficient resources for ongoing projects.

Immunome, Inc. (Nasdaq: IMNM), a biopharmaceutical company specializing in first-in-class antibody therapeutics, announced that its President and CEO, Purnanand Sarma, Ph.D., will present at the Stifel Healthcare Conference on November 15, 2021, at 8:00 a.m. ET. Interested listeners can access the live audio webcast via the Investor Relations section of Immunome's website, with a replay available for 30 days post-event. Immunome focuses on developing therapies for oncology and infectious diseases, including COVID-19, leveraging its proprietary human memory B cell platform.

Immunome (Nasdaq: IMNM) has submitted a preprint manuscript detailing the preclinical efficacy of its SARS-CoV-2 antibody cocktail, IMM-BCP-01. This cocktail includes three monoclonal antibodies targeting regions of the spike protein, showing significant viral load reduction in infected hamsters. In tests, IMM-BCP-01 demonstrated a potent reduction of live viral titers by approximately 3.2 - 4 logs. This research indicates broad protective capabilities against multiple variants, supporting the potential for non-intravenous delivery in humans.

Immunome, Inc. (Nasdaq: IMNM) presented findings on its anti-interleukin-38 monoclonal antibody program at the 2021 AACR-NCI-EORTC International Conference. The presentation revealed that the antibody effectively binds to IL-38, preventing its interaction with receptors and enhancing myeloid cell activity in vitro. In murine tumor models, the antibody significantly inhibited tumor growth. This data suggests that blocking IL-38 could potentially reverse immune suppression in tumors, providing a promising avenue for cancer treatment.