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IMUNON Public Webcast Highlights Resilience and Innovation in Pursuit of the First Approved Immunotherapy for Ovarian Cancer

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IMUNON (Nasdaq: IMNN) hosted a public webcast on Nov 10, 2025 presenting translational and clinical data for its DNA-mediated immunotherapy IMNN-001.

Speakers included cancer key opinion leaders, principal investigators from the Phase 3 OVATION 3 and Phase 2 MRD trials, clinicians, statistical experts and IMUNON executives. The event highlighted clinical findings that the company described as showing significant potential for women with advanced ovarian cancer.

A recording and symposium slides are available on IMUNON’s Scientific Presentations page at https://investors.imunon.com/scientific-presentations.

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News Market Reaction 6 Alerts

-6.25% News Effect
+3.5% Peak Tracked
-11.7% Trough Tracked
-$672K Valuation Impact
$10M Market Cap
1.5x Rel. Volume

On the day this news was published, IMNN declined 6.25%, reflecting a notable negative market reaction. Argus tracked a peak move of +3.5% during that session. Argus tracked a trough of -11.7% from its starting point during tracking. Our momentum scanner triggered 6 alerts that day, indicating moderate trading interest and price volatility. This price movement removed approximately $672K from the company's valuation, bringing the market cap to $10M at that time.

Data tracked by StockTitan Argus on the day of publication.

Webcast Recording and Symposium Slides Now Available

LAWRENCEVILLE, N.J., Nov. 10, 2025 (GLOBE NEWSWIRE) -- IMUNON, Inc. (Nasdaq: IMNN), a clinical-stage company in Phase 3 development with its DNA-mediated immunotherapy, today hosted a compelling public webcast, where cancer key opinion leaders, principal investigators from the Phase 3 OVATION 3 and Phase 2 minimal residual disease (MRD) trials, clinicians, statistical experts and IMUNON executives shared critical insights into the disease and translational data, along with compelling clinical data highlighting the significant potential of IMNN-001 for women with advanced ovarian cancer.

A webcast of the live event and presentation materials are available on the “Scientific Presentations” page of the IMUNON website at https://investors.imunon.com/scientific-presentations.

About IMUNON

IMUNON is a clinical-stage biotechnology company focused on advancing a portfolio of innovative treatments that harness the body’s natural mechanisms to generate safe, effective and durable responses across a broad array of human diseases, constituting a differentiating approach from conventional therapies. IMUNON is developing its non-viral DNA technology across its modalities. The first modality, TheraPlas®, is developed for the gene-based delivery of cytokines and other therapeutic proteins in the treatment of solid tumors where an immunological approach is deemed promising. The second modality, PlaCCine®, is developed for the gene delivery of viral antigens that can elicit a strong immunological response.

The Company’s lead clinical program, IMNN-001, is a DNA-based immunotherapy for the localized treatment of advanced ovarian cancer that has completed multiple clinical trials including one Phase 2 clinical trial (OVATION 2) and is currently conducting a Phase 3 clinical trial (OVATION 3). IMNN-001 works by instructing the body to produce safe and durable levels of powerful cancer-fighting molecules, such as interleukin-12 and interferon gamma, at the tumor site. Additionally, the Company has completed dosing in a first-in-human study of its COVID-19 booster vaccine (IMNN-101). The Company will continue to leverage these modalities and to advance, either directly or through partnership, the technological frontier of plasmid DNA to better serve patients with difficult-to-treat conditions. For more information, please visit www.imunon.com.

Forward-Looking Statements

IMUNON wishes to inform readers that forward-looking statements in this news release are made pursuant to the “safe harbor” provisions of the Private Securities Litigation Reform Act of 1995. All statements, other than statements of historical fact, including, but not limited to, statements regarding the timing of enrollment of the Company’s clinical trials, the potential of any therapies developed by the Company to fulfill unmet medical needs, the market potential for the Company’s products, if approved, the potential efficacy and safety profile of our product candidates, and the Company’s plans and expectations with respect to its development programs more generally, are forward-looking statements. We generally identify forward-looking statements by using words such as “may,” “will,” “expect,” “plan,” “anticipate,” “estimate,” “intend” and similar expressions (as well as other words or expressions referencing future events, conditions or circumstances). Readers are cautioned that such forward-looking statements involve risks and uncertainties including, without limitation, uncertainties relating to unforeseen changes in the course of research and development activities and in clinical trials, including the fact that interim results are not necessarily indicative of final results; the uncertainties of and difficulties in analyzing interim clinical data; the significant expense, time and risk of failure in conducting clinical trials; the need for IMUNON to evaluate its future development plans; possible actions by customers, suppliers, competitors or regulatory authorities; and other risks detailed from time to time in IMUNON’s filings with the Securities and Exchange Commission. IMUNON assumes no obligation, except to the extent required by law, to update or supplement forward-looking statements that become untrue because of subsequent events, new information or otherwise.

Contacts:

Media Investors
Jenna UrbanPeter Vozzo
CG lifeICR Healthcare
212-253-8881443-213-0505
jurban@cglife.competer.vozzo@icrhealthcare.com

FAQ

Where can I watch IMUNON's Nov 10, 2025 webcast on IMNN-001 clinical data?

A recording and presentation slides are available on the company’s Scientific Presentations page at https://investors.imunon.com/scientific-presentations.

Which trials were discussed in the IMUNON Nov 10, 2025 webcast for IMNN (IMNN-001)?

Speakers reviewed data and insights from the Phase 3 OVATION 3 trial and the Phase 2 MRD trial.

Who spoke at IMUNON’s public webcast about IMNN-001 on Nov 10, 2025?

The webcast featured cancer key opinion leaders, principal investigators from the cited trials, clinicians, statistical experts and IMUNON executives.

What clinical population was the focus of IMUNON’s Nov 10, 2025 presentation?

The presentations focused on the potential of IMNN-001 for women with advanced ovarian cancer.

Does the Nov 10, 2025 IMUNON webcast include statistical and translational data for IMNN-001?

Yes; the webcast included translational data and statistical perspectives alongside clinical findings.

How can investors find the symposium slides from IMUNON’s Nov 10, 2025 event for IMNN?

Investors can download the presentation materials from the Scientific Presentations page on the company’s investor website.
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Biotechnology
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United States
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