Welcome to our dedicated page for Imunon news (Ticker: IMNN), a resource for investors and traders seeking the latest updates and insights on Imunon stock.
Imunon, Inc. (IMNN) generates frequent news as a clinical-stage biotechnology company advancing DNA-mediated immunotherapies and DNA vaccine technologies. Most coverage centers on its lead program, IMNN-001, a TheraPlas-based IL-12 DNA immunotherapy in Phase 3 development for newly diagnosed advanced ovarian cancer, and on its PlaCCine DNA vaccine platform, including the IMNN-101 COVID-19 booster candidate.
Investors following IMNN news can expect regular updates on clinical trial progress, such as enrollment milestones, translational data and survival outcomes from the OVATION 2 Phase 2 study and the pivotal OVATION 3 Phase 3 trial. Company releases describe how IMNN-001 is being evaluated in combination with standard neoadjuvant and adjuvant chemotherapy, and how biomarker data show shifts in the tumor microenvironment toward more active anti-tumor immunity.
Another major news theme is scientific and medical conference activity. Imunon frequently announces posters and presentations at meetings such as the Society for Immunotherapy of Cancer, the European Society for Medical Oncology, the International Gynecologic Cancer Society and specialized ovarian cancer conferences. These items often include new translational data on immune cell changes, cytokine profiles and clinical outcomes associated with IMNN-001.
Imunon also issues news on corporate and financial developments, including quarterly financial results, R&D Day events, capital markets transactions like registered direct offerings and at-the-market equity programs, and Nasdaq listing-related updates. For the PlaCCine platform, news items highlight proof-of-concept data for IMNN-101 and presentations at international vaccine conferences.
For readers tracking IMNN, this news feed provides a consolidated view of clinical milestones, scientific recognition, financing activities and regulatory communications that shape the company’s development trajectory in oncology and DNA vaccine research.
IMUNON (NASDAQ: IMNN) recently shared key achievements from 2022 and outlined strategic objectives for 2023. Dr. Corinne Le Goff, CEO, highlighted a transformative shift, including the company’s rebranding and an innovative focus on DNA-based immunotherapies and vaccines. The company raised over $60 million from common stock sales, ending Q3 2022 with $43.4 million in cash and investments. Significant milestones include the enrollment of 110 patients in the OVATION 2 Study for the IL-12 gene therapy, IMNN-001, and advancements in the PLACCINE vaccine technology, showing promising results in animal studies. They anticipate filing an IND application for a COVID-19 booster vaccine in 2023.
IMUNON (NASDAQ: IMNN) announces the start of patient enrollment in a collaboration with Break Through Cancer to evaluate IMNN-001 in combination with bevacizumab for advanced ovarian cancer. This Phase 1/2 trial at MD Anderson aims to enroll 50 patients, focusing on minimal residual disease detection and progression-free survival. Initial results are expected within a year, with final data anticipated in three years. IMUNON will invest $2.0-$2.5 million towards the trial, which aims to enhance treatment outcomes for Stage III/IV ovarian cancer patients, characterized by low cure rates.
IMUNON, Inc. (NASDAQ: IMNN) has secured $1.6 million from the sale of unused New Jersey net operating losses (NOLs) through the NJEDA's Technology Business Tax Certificate Transfer program. This funding strengthens its balance sheet and extends its operational runway into 2025. The company plans to sell an additional $1.8 million in NOLs in 2023. In the past five years, IMUNON has generated over $18 million from NOL sales, enhancing its capacity for research and development amid challenging capital markets.
IMUNON (NASDAQ: IMNN) has signed a collaborative research agreement with The Wistar Institute to develop new vaccine formulations using IMUNON’s PLACCINE modality. This partnership aims to expand vaccine targets and optimize product quality. Dr. Corinne Le Goff, CEO of IMUNON, expressed enthusiasm for working with Wistar's expertise in immunology and infectious diseases. IMUNON is focused on advancing nucleic acid-based therapies, including its lead program, GEN-1, currently in Phase II for advanced ovarian cancer. The company is also validating its PLACCINE platform for a vaccine candidate against SARS-CoV-2.
IMUNON, Inc. (NASDAQ: IMNN) announced the grant of stock options and restricted stock totaling 23,000 shares to incentivize four new employees. The inducement options allow for the purchase of 19,000 shares at an exercise price of $1.40, the closing price on December 13, 2022. These options will vest over three years, while the restricted stock vests after one year. IMUNON focuses on DNA-based immunotherapy and vaccines, with its lead program, GEN-1, in Phase II for advanced ovarian cancer treatment. The company aims to leverage its technological platforms for innovative treatments across various diseases.
IMUNON, Inc. (NASDAQ: IMNN) presented its innovative PLACCINE vaccine modality at the World Vaccine & Immunotherapy Congress in San Diego. The presentation highlighted proof-of-concept data demonstrating immunogenic responses and durable viral clearance from SARS-CoV-2 in animal models. IMUNON's non-viral, plasmid DNA vaccine showed effective results and stability for up to six months. The PLACCINE platform offers advantages such as a durable immune response, safe delivery, and flexible manufacturing, aiming to revolutionize vaccine development.
IMUNON (NASDAQ: IMNN) announced participation in A.G.P.’s Biotech Conference from November 30 to December 1, 2022. Dr. Corinne Le Goff and Mr. Jeffrey Church will represent the company in one-on-one virtual investor meetings. Investors interested in meeting with IMUNON management can contact their A.G.P. representative. The company's lead program, GEN-1, is an innovative DNA-based immunotherapy targeting advanced ovarian cancer, currently in Phase II trials. More details can be found in IMUNON's corporate presentation linked in the announcement.
IMUNON (NASDAQ: IMNN) announced a $375,000 investment in Transomic Technologies, a private firm specializing in CRISPR and gene expression tools. This strategic move aims to enhance IMUNON's PLACCINE DNA vaccine platform by utilizing Transomic's vector construction services for developing plasmids. Executive Chairman Michael H. Tardugno will join Transomic's board. The investment supports ongoing progress in IMUNON's DNA vaccine development against infectious diseases like SARS-CoV-2, showcasing the platform's rapid adaptability to emerging variants.
IMUNON, Inc. (NASDAQ: IMNN) reported its Q3 2022 financial results, showing a net loss of $6.1 million ($0.87 per share) compared to $5.4 million ($0.94 per share) in Q3 2021. Operating expenses rose by 21% to $6.3 million. Key highlights include the completion of enrollment in the Phase I/II OVATION 2 study for GEN-1 in advanced ovarian cancer and promising results from preclinical studies of its PLACCINE vaccine technology. The company’s cash runway extends into 2025, bolstered by recent capital raises. Topline results from GEN-1 are expected in H1 2024.
IMUNON (NASDAQ: IMNN) has signed an agreement with Acuitas Therapeutics to evaluate the use of Acuitas' proprietary lipid delivery technology with IMUNON's PLACCINE nucleic acid vaccine constructs. This collaboration aims at expanding applications of PLACCINE, which has shown promise in non-human primate studies against SARS-CoV-2. The PLACCINE platform features multiple coding regions for broader immunity and is designed for easy modification to create vaccines for various infectious diseases. IMUNON continues to advance its innovative therapies leveraging its unique delivery systems.