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Imunon, Inc. reports developments as a clinical-stage biotechnology company advancing non-viral DNA technologies for immunotherapy and vaccines. Its lead candidate, IMNN-001, is a DNA-based interleukin-12 immunotherapy being developed for localized treatment of newly diagnosed advanced ovarian cancer through the OVATION clinical program.
Company news commonly covers clinical data from OVATION studies, Phase 3 development activity, financial results and business updates, and portfolio work around the TheraPlas platform for cytokine and therapeutic-protein delivery and the PlaCCine platform for viral-antigen delivery. Updates also include capital discipline, organization changes, and presentations of translational or proof-of-concept data.
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IMUNON, a clinical-stage drug-development company, presented findings on its DNA-based immunotherapy, IMNN-001, at the AACR Annual Meeting on April 18, 2023. The study evaluated three dosing regimens for the treatment of advanced ovarian cancer using a mouse model. IMNN-001, in Phase 2 trials, showed that a biweekly dosing regimen was comparable to weekly dosing but more effective than a three-week regimen in reducing tumor burden and mortality. These results support further exploration of biweekly dosing in human studies. Dr. Corinne Le Goff, CEO of IMUNON, expressed excitement over the presentation and highlighted the implications for upcoming clinical studies involving IMNN-001 and bevacizumab.
IMUNON, Inc. (NASDAQ: IMNN) announced its 2022 financial results, reporting a net loss of $35.9 million, or $5.03 per share, an increase from $20.8 million in 2021. Operating expenses rose to $25.4 million, up 18% year-over-year. The company made progress in its clinical programs, including completing enrollment in the Phase 1/2 OVATION 2 Study for IMNN-001 in advanced ovarian cancer. IMUNON reported cash of $38.9 million as of December 31, 2022, expected to fund operations into 2025. The company also highlighted promising preclinical data for its PLACCINE vaccine technology and plans to file an Investigational New Drug (IND) application for a COVID-19 booster vaccine in 2023.
IMUNON (NASDAQ: IMNN), a clinical-stage drug-development company, will host a conference call on March 30, 2023, at 11:00 a.m. ET to discuss its Q4 and full-year financial results for 2022. The company will also update on IMNN-001, its Phase 2 immunotherapy targeting advanced ovarian cancer, and its preclinical studies of PLACCINE, a novel plasmid technology aiming to outperform current mRNA vaccines. Interested parties can join via phone or listen online, with an archived replay available until April 13, 2023. IMUNON focuses on DNA-mediated immunotherapy and next-gen vaccines aimed at various diseases.