Inovio Pharmaceu Stock Price, News & Analysis

INOVIO (NASDAQ: INO), a biotechnology company specializing in DNA medicines, has scheduled its first quarter 2025 financial results announcement for May 13, 2025, after market close.

The company, which focuses on developing treatments for HPV-associated diseases, cancers, and infectious diseases, will host a live conference call and webcast at 4:30 p.m. ET on the same day. The event will include:

• A general business update presentation
• Live Q&A session with analysts
• Webcast access through http://ir.inovio.com/events-and-presentations/default.aspx

The webcast will be available for replay for 90 days following the event. This listen-only event provides investors and stakeholders an opportunity to stay updated on INOVIO's financial performance and business developments.

INOVIO (NASDAQ:INO) has announced its participation in several upcoming scientific conferences to present data on its lead candidate INO-3107 and DNA medicine technologies. At the National HPV Conference in Indianapolis on April 15, the company will present results showing a 72% overall response rate in Year 1 for treating Recurrent Respiratory Papillomatosis caused by HPV-6 & 11.

The company will also participate in the World Vaccine Congress in Washington, DC (April 21-23), where they will discuss their DNA-encoded monoclonal antibody (DMAb™) technology and DNA immunotherapeutics for cancer and viral diseases. Additionally, INOVIO will present at the Festival of Biologics in San Diego on April 23, focusing on INO-3107 for Recurrent Respiratory Papillomatosis. Abstracts will be available on INOVIO's website after the presentations.

INOVIO (NASDAQ: INO) reported its Q4 and full-year 2024 financial results, highlighting significant progress toward its first Biologics License Application (BLA) for INO-3107, targeting recurrent respiratory papillomatosis (RRP). The company resolved manufacturing issues and plans to begin rolling BLA submission in mid-2025.

Key financial metrics for 2024 include:

• Cash position: $94.1M (down from $145.3M in 2023)
• Annual revenue: $218,000 (decreased from $832,000 in 2023)
• Net loss: $107.3M or $3.95 per share (improved from $135.1M in 2023)
• R&D expenses: $75.6M (reduced from $86.7M in 2023)

Clinical highlights include promising durability data showing 50% of RRP patients achieved Complete Response in year 2, and positive interim results from their DNA-encoded monoclonal antibodies (DMAb) COVID-19 trial. The company projects its current cash position will support operations into Q1 2026, with an estimated Q1 2025 operational net cash burn of $27M.

INOVIO (NASDAQ: INO) has announced promising interim results from its ongoing Phase 1 proof-of-concept trial for DNA-encoded Monoclonal Antibodies (DMAbs) targeting COVID-19. The trial demonstrated significant achievements in durability and safety:

Key findings include:

• 100% of participants (24/24) maintained stable DMAb levels through week 72
• No anti-drug antibodies (ADA) detected across ~1,000 blood samples
• Well-tolerated with only mild, temporary injection site reactions
• Expressed DMAbs successfully bound to SARS-CoV-2 Spike protein RBD through week 72

The study, conducted in collaboration with The Wistar Institute, AstraZeneca, and the Perelman School of Medicine at the University of Pennsylvania, represents a potential breakthrough in overcoming traditional monoclonal antibody production challenges. The technology shows promise for treating infectious diseases, cancer, and metabolic disorders through long-term therapeutic protein expression.

INOVIO (NASDAQ:INO), a biotechnology company specializing in DNA medicines for HPV-associated diseases, cancers, and infectious diseases, has scheduled the release of its fourth quarter and year-end 2024 financial results for March 18, 2025, after market close.

The company will host a live conference call and webcast at 4:30 p.m. ET on the same day to discuss the financial results and provide a business update. The webcast will include a Q&A session with analysts and will be available for replay for 90 days through the investor relations section of INOVIO's website.

INOVIO (NASDAQ: INO) announced peer-reviewed data from its Phase 1/2 clinical trial of INO-3107 for treating recurrent respiratory papillomatosis (RRP) in Nature Communications. The trial demonstrated significant clinical benefits, with 81.3% (26/32) of patients requiring fewer surgeries post-treatment compared to the previous year. 28.1% (9/32) of patients achieved Complete Response, requiring no surgical intervention.

The treatment showed strong safety profile with only 41% reporting treatment-related adverse events, mostly mild injection site pain (31%) and fatigue (9%). INO-3107 induced lasting T cell responses specific to HPV-6 and HPV-11, with evidence of immune cells traveling to affected tissues.

INOVIO plans to submit its biologics license application (BLA) in mid-2025, seeking rolling submission and priority review. If approved, INO-3107 would become the first DNA medicine approved in the United States.

INOVIO (NASDAQ:INO) announced that it will present immunological activity data for INO-3107 at the American Association for Cancer Research – Immuno-Oncology Discovery and Innovation in Cancer Immunology conference, scheduled for February 23-26, 2025. The poster presentation will focus on the loss of detectable HPV-6 in Recurrent Respiratory Papillomatosis patients following INO-3107 treatment, specifically highlighting the induction of emergent T cells in patients who showed durable complete clinical response. The abstract will be made available on INOVIO's website after the conference.

INOVIO (NASDAQ: INO), a biotechnology company specializing in DNA medicines for HPV-associated diseases, cancer, and infectious diseases, has announced its participation in the Oppenheimer 35th Annual Healthcare Life Sciences Conference.

The company's President and CEO, Dr. Jacqueline Shea, along with Chief Medical Officer Dr. Michael Sumner, will deliver a presentation on Wednesday, February 12, 2025, from 3:20 to 3:50 PM ET. The management team will also conduct one-on-one meetings with registered investors during the conference.

Interested parties can access the presentation through a webcast available on INOVIO's Investor Relations Events page, with replay access available for 90 days following the presentation.

INOVIO highlighted its anticipated 2025 milestones and 2024 achievements. The company plans to submit a biologics license application (BLA) for INO-3107 by mid-2025 for treating recurrent respiratory papillomatosis (RRP). Key 2024 accomplishments include positive durability data showing 50% of RRP patients achieved complete response requiring no surgery by year two, with 88% maintaining complete response through year two and 63% into year three.

The company expects to initiate a confirmatory trial at 20 U.S. academic centers with approximately 100 patients. INOVIO strengthened its financial position with over $60 million from equity offerings in 2024, reporting $84.4 million in cash and equivalents as of September 2024. The company is also progressing with INO-3112 for HPV-related cancer and other pipeline products including INO-4201 for Ebola and DNA monoclonal antibody programs.