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Century Therapeutics to Host Live Fireside Chat Focused on Newly Prioritized Preclinical Cell Therapy Programs for Autoimmune Diseases and Cancer on Tuesday, April 22, 2025

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Century Therapeutics (NASDAQ: IPSC) has announced a live fireside chat scheduled for Tuesday, April 22, 2025, at 10:00 a.m. EDT to discuss their prioritized preclinical cell therapy programs. The event will showcase three key investigational therapies:

  • CNTY-308: A CD19-targeted CAR-iT cell therapy
  • CNTY-341: A CD19/CD22 dual-targeted CAR-iT cell therapy
  • A solid tumor CAR iT program focusing on Nectin-4 CAR and other validated targets

All programs utilize advanced iPSC-derived 'tunable' CD4+/CD8+ ab T cells and incorporate the company's proprietary Allo-Evasion™ 5.0 technology, designed for comprehensive immune evasion. The presentation will also explore the potential expansion of their selective iPSC differentiation expertise to non-immune effector cells. The event will be accessible through Century's website, with a replay available for at least 30 days.

Century Therapeutics (NASDAQ: IPSC) ha annunciato un incontro live previsto per martedì 22 aprile 2025 alle 10:00 EDT, durante il quale discuterà i suoi programmi prioritari di terapia cellulare preclinica. L'evento presenterà tre terapie sperimentali chiave:

  • CNTY-308: una terapia con cellule CAR-T mirata al CD19
  • CNTY-341: una terapia con cellule CAR-T dual-target che agisce su CD19/CD22
  • Un programma CAR-T per tumori solidi focalizzato su Nectin-4 CAR e altri target convalidati

Tutti i programmi utilizzano cellule ab T CD4+/CD8+ derivate da iPSC avanzate e “regolabili”, integrando la tecnologia proprietaria Allo-Evasion™ 5.0, progettata per un’evasione immunitaria completa. La presentazione esplorerà inoltre la possibile estensione della loro esperienza nella differenziazione selettiva di iPSC verso cellule effettrici non immunitarie. L’evento sarà accessibile tramite il sito web di Century, con una replica disponibile per almeno 30 giorni.

Century Therapeutics (NASDAQ: IPSC) ha anunciado un chat en vivo programado para el martes 22 de abril de 2025 a las 10:00 a.m. EDT para discutir sus programas prioritarios de terapia celular preclínica. El evento presentará tres terapias experimentales clave:

  • CNTY-308: una terapia celular CAR-T dirigida a CD19
  • CNTY-341: una terapia celular CAR-T de doble objetivo dirigida a CD19/CD22
  • Un programa CAR-T para tumores sólidos centrado en Nectin-4 CAR y otros objetivos validados

Todos los programas utilizan células ab T CD4+/CD8+ derivadas de iPSC avanzadas y “ajustables”, e incorporan la tecnología propietaria Allo-Evasion™ 5.0, diseñada para una evasión inmune completa. La presentación también explorará la posible expansión de su experiencia en diferenciación selectiva de iPSC hacia células efectoras no inmunes. El evento será accesible a través del sitio web de Century, con una repetición disponible por al menos 30 días.

Century Therapeutics (NASDAQ: IPSC)는 2025년 4월 22일 화요일 오전 10시 EDT에 라이브 파이어사이드 채팅을 개최하여 우선 순위가 높은 전임상 세포 치료 프로그램에 대해 논의할 예정입니다. 이번 행사에서는 세 가지 주요 임상 시험 치료법을 선보입니다:

  • CNTY-308: CD19 표적 CAR-T 세포 치료제
  • CNTY-341: CD19/CD22 이중 표적 CAR-T 세포 치료제
  • 넥틴-4 CAR 및 기타 검증된 표적에 중점을 둔 고형 종양 CAR-T 프로그램

모든 프로그램은 고급 iPSC 유래의 '조절 가능한' CD4+/CD8+ ab T 세포를 사용하며, 회사의 독점 기술인 Allo-Evasion™ 5.0을 도입하여 포괄적인 면역 회피를 구현합니다. 발표에서는 또한 비면역 효과 세포로의 선택적 iPSC 분화 전문성 확장 가능성도 탐구할 예정입니다. 행사는 Century 웹사이트를 통해 접속할 수 있으며, 최소 30일간 다시보기 서비스가 제공됩니다.

Century Therapeutics (NASDAQ : IPSC) a annoncé une discussion en direct prévue le mardi 22 avril 2025 à 10h00 EDT pour présenter ses programmes prioritaires de thérapie cellulaire préclinique. L'événement mettra en avant trois thérapies expérimentales clés :

  • CNTY-308 : une thérapie cellulaire CAR-T ciblant le CD19
  • CNTY-341 : une thérapie CAR-T à double ciblage CD19/CD22
  • Un programme CAR-T pour tumeurs solides axé sur le Nectin-4 CAR et d’autres cibles validées

Tous les programmes utilisent des cellules ab T CD4+/CD8+ dérivées d’iPSC avancées et « modulables », intégrant la technologie propriétaire Allo-Evasion™ 5.0, conçue pour une évasion immunitaire complète. La présentation explorera également l’expansion potentielle de leur expertise en différenciation sélective d’iPSC vers des cellules effectrices non immunitaires. L’événement sera accessible via le site web de Century, avec une rediffusion disponible pendant au moins 30 jours.

Century Therapeutics (NASDAQ: IPSC) hat einen Live-Fireside-Chat für Dienstag, den 22. April 2025, um 10:00 Uhr EDT angekündigt, um ihre priorisierten präklinischen Zelltherapieprogramme zu besprechen. Die Veranstaltung wird drei wichtige experimentelle Therapien vorstellen:

  • CNTY-308: Eine CAR-T-Zelltherapie, die auf CD19 abzielt
  • CNTY-341: Eine dual-target CAR-T-Zelltherapie, die CD19/CD22 anspricht
  • Ein CAR-T-Programm für solide Tumore mit Fokus auf Nectin-4 CAR und weitere validierte Ziele

Alle Programme verwenden fortschrittliche, von iPSC abgeleitete, „anpassbare“ CD4+/CD8+ ab T-Zellen und integrieren die firmeneigene Allo-Evasion™ 5.0-Technologie, die für umfassende Immunflucht entwickelt wurde. Die Präsentation wird auch die mögliche Erweiterung ihrer Expertise in der selektiven iPSC-Differenzierung auf nicht-immune Effektorzellen behandeln. Die Veranstaltung ist über die Website von Century zugänglich, mit einer Wiedergabe, die mindestens 30 Tage verfügbar sein wird.

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PHILADELPHIA, April 15, 2025 (GLOBE NEWSWIRE) -- Century Therapeutics, Inc. (‘Century’, NASDAQ: IPSC), an innovative biotechnology company developing induced pluripotent stem cell (iPSC)-derived cell therapies in autoimmune disease and cancer, today announced that company management will host a live fireside chat on Tuesday, April 22, 2025, at 10:00 a.m. EDT to discuss details and data for its prioritized preclinical cell therapy programs targeting autoimmune diseases and cancer.

The event will feature discussion of CNTY-308, a CD19-targeted CAR-iT investigational cell therapy, CNTY-341, a CD19/CD22 dual-targeted CAR-iT investigational cell therapy, and the company’s first solid tumor CAR iT investigational program exploiting Nectin-4 CAR and other validated targets. Each of these programs is anchored by advanced iPSC-derived ’tunable’ CD4+/CD8+ ab T cells. In addition, each of these programs is engineered with the company’s proprietary immune evasion technology, Allo-Evasion™ 5.0, which is designed to enable holistic evasion of T cell, NK cell, and humoral immunity. The discussion will also highlight the potential for the company’s expertise in selective iPSC differentiation to extend to non-immune effector cells.

The live event can be accessed on the Investors page of Century’s website at www.centurytx.com. A replay will be available on the company’s website shortly following the completion of the event and will be available for at least 30 days.

About Century Therapeutics
Century Therapeutics (NASDAQ: IPSC) is a clinical-stage biotechnology company leveraging its expertise in cellular reprogramming, genetic engineering, and manufacturing to develop cell therapies with the potential to provide meaningful advantages over existing cell therapies. Century’s genetically engineered, iPSC-derived cell therapy pipeline includes programs designed to address autoimmune diseases and cancers. Century believes its commitment to developing off-the-shelf cell therapies will expand patient access and provide an opportunity to advance the course of autoimmune disease and cancer care. For more information on Century Therapeutics, please visit www.centurytx.com and connect with us on LinkedIn.

Forward-Looking Statements
This press release and statements of our management made in connection therewith contain forward-looking statements within the meaning of, and made pursuant to the safe harbor provisions of, The Private Securities Litigation Reform Act of 1995. All statements contained in this press release, other than statements of historical facts or statements that relate to present facts or current conditions, including but not limited to, statements regarding our clinical development plans and timelines are forward-looking statements. These statements involve known and unknown risks, uncertainties and other important factors that may cause our actual results, performance, or achievements to be materially different from any future results, performance or achievements expressed or implied by the forward-looking statements. In some cases, you can identify forward-looking statements by terms such as “may,” “might,” “will,” “should,” “expect,” “plan,” “aim,” “seek,” “anticipate,” “could,” “intend,” “target,” “project,” “contemplate,” “believe,” “estimate,” “predict,” “forecast,” “potential” or “continue” or the negative of these terms or other similar expressions. The forward-looking statements in this press release are only predictions. We have based these forward-looking statements largely on our current expectations and projections about future events and financial trends that we believe may affect our business, financial condition, and results of operations. These forward-looking statements speak only as of the date of this press release and are subject to a number of risks, uncertainties and assumptions, some of which cannot be predicted or quantified and some of which are beyond our control, including, among others: our ability to successfully advance our current and future product candidates through development activities, preclinical studies, and clinical trials; our dependence on the success of our lead product candidate, CNTY-101; our ability to progress CNTY-101 through clinical development; our ability to meet development milestones on anticipated timelines; uncertainties inherent in the results of preliminary data, pre-clinical studies and earlier-stage clinical trials, which may not be predictive of final results or the results of later-stage clinical trials; our ability to obtain FDA clearance of our future IND submissions and commence and complete clinical trials on expected timelines, or at all; our reliance on the maintenance of certain key collaborative relationships for the manufacturing and development of our product candidates; the timing, scope and likelihood of regulatory filings and approvals, including final regulatory approval of our product candidates; the impact of geopolitical issues, banking instability and inflation on our business and operations, supply chain and labor force; the performance of third parties in connection with the development of our product candidates, including third parties conducting our clinical trials as well as third-party suppliers and manufacturers; our ability to successfully commercialize our product candidates and develop sales and marketing capabilities, if our product candidates are approved; our ability to recruit and maintain key members of management and our ability to maintain and successfully enforce adequate intellectual property protection. These and other risks and uncertainties are described more fully in the “Risk Factors” section of our most recent filings with the Securities and Exchange Commission and available at www.sec.gov. You should not rely on these forward-looking statements as predictions of future events. The events and circumstances reflected in our forward-looking statements may not be achieved or occur, and actual results could differ materially from those projected in the forward-looking statements. Moreover, we operate in a dynamic industry and economy. New risk factors and uncertainties may emerge from time to time, and it is not possible for management to predict all risk factors and uncertainties that we may face. Except as required by applicable law, we do not plan to publicly update or revise any forward-looking statements contained herein, whether as a result of any new information, future events, changed circumstances or otherwise.

For More Information:

Century Therapeutics
Morgan Conn, PhD
Chief Financial Officer
investor.relations@centurytx.com

JPA Health
Sarah McCabe
smccabe@jpa.com


FAQ

What new cell therapy programs will Century Therapeutics (IPSC) discuss on April 22, 2025?

Century will discuss CNTY-308 (CD19-targeted), CNTY-341 (CD19/CD22 dual-targeted), and a solid tumor program focusing on Nectin-4 CAR therapies.

What is the Allo-Evasion™ 5.0 technology used in Century Therapeutics' (IPSC) cell therapies?

Allo-Evasion™ 5.0 is Century's proprietary technology designed to enable holistic evasion of T cell, NK cell, and humoral immunity in their cell therapies.

When and where can investors access Century Therapeutics' (IPSC) April 2025 fireside chat?

The fireside chat will be accessible on April 22, 2025, at 10:00 a.m. EDT through Century's website (www.centurytx.com), with a 30-day replay available.

What types of diseases are targeted by Century Therapeutics' (IPSC) new cell therapy programs?

The programs target both autoimmune diseases and cancer, including solid tumors, using iPSC-derived 'tunable' CD4+/CD8+ ab T cells.
Century Therapeutics, Inc.

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