Iterum Therapeutics Plc Stock Price, News & Analysis

Dublin, Ireland and Chicago, April 20, 2023 – Iterum Therapeutics (Nasdaq: ITRM) announced the presentation of two posters at the 33rd Annual European Congress of Clinical Microbiology and Infectious Disease (ECCMID) in Copenhagen on April 17, 2023. The presentations focused on a novel analysis method called Desirability of Outcome Ranking (DOOR) applied to Phase 3 trials of their antibiotic sulopenem for uncomplicated (uUTI) and complicated urinary tract infections (cUTI). Key findings demonstrated that oral sulopenem was more effective than ciprofloxacin for uUTI and comparable to ertapenem for cUTI. This approach, though not yet a primary endpoint for regulatory approval, reflects a commitment to evaluating patient outcomes comprehensively. Iterum is advancing sulopenem, an innovative treatment for multi-drug resistant infections, with QIDP and Fast Track designations for multiple indications.

Iterum Therapeutics (Nasdaq: ITRM) reported its financial results for Q4 and full year 2022, showing a net loss of $5.1 million for Q4 and $44.4 million for the entire year, improving from a net loss of $4.2 million and $91.6 million in 2021. The company focuses on developing oral and IV antibiotics to combat multi-drug resistant infections. Enrollment in the REASSURE clinical trial for uUTI treatment is ongoing, with an interim analysis expected later in 2023. Cash reserves as of December 31, 2022, stand at $60.8 million, projected to sustain operations until mid-2024. The company also received two new patents extending its portfolio until at least 2039.

Iterum Therapeutics, a clinical-stage pharmaceutical company, will announce its Q4 and full-year 2022 financial results before the U.S. markets open on March 16, 2023. Management will host a conference call at 8:30 a.m. ET to discuss the results and provide a business update. Sulopenem, Iterum's lead compound, is in Phase 3 clinical development and has received QIDP and Fast Track designations for multiple indications. Investors can access the call via dial-in or audio webcast through the company's website.

Iterum Therapeutics plc (Nasdaq: ITRM) announced a Notice of Allowance from the USPTO for its patent on the combination of sulopenem etzadroxil and probenecid, aimed at treating uncomplicated urinary tract infections.

This new patent, set to expire in April 2039, strengthens Iterum's position in the market for oral antibiotics, following a recently issued patent covering the bilayer tablet formulation. The company is currently enrolling patients in a Phase 3 clinical trial for oral sulopenem and anticipates updates after reaching 50% enrollment.