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Jazz Pharmaceuticals (JAZZ) Stock News, Dec 2025-Apr 2026

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Welcome to our dedicated page for Jazz Pharmaceuticals news (Ticker: JAZZ), a resource for investors and traders seeking the latest updates and insights on Jazz Pharmaceuticals stock.

Jazz Pharmaceuticals plc reports developments across a global biopharma portfolio focused on rare diseases, including epilepsies, cancers and sleep disorders. Recurring updates cover commercial performance for Xywav, Epidiolex and oncology products, plus medical-conference data and real-world evidence for neuroscience and oncology programs.

Company news also includes regulatory and clinical progress for Ziihera (zanidatamab-hrii) in HER2-expressing tumors, including gastroesophageal adenocarcinoma and biliary tract cancer, along with research involving Zepzelca, Modeyso and other pipeline candidates. Updates frequently address financial results, guidance, investor conferences, collaborations and portfolio strategy.

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Jazz Pharmaceuticals (Nasdaq: JAZZ) will participate in the 25th Annual Needham Healthcare Conference on April 15, 2026. Management will join a fireside chat at 8:45 a.m. PT / 11:45 a.m. ET / 4:45 p.m. IST.

An audio webcast will be available via the company’s Investors site, with a replay archived for 30 days.

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American Nutrition Association and Jazz Pharmaceuticals (NYSE:JAZZ) announced a collaboration on March 24, 2026 to advance evidence-based sodium reduction education for people with narcolepsy and idiopathic hypersomnia. The initiative emphasizes sodium’s role in blood pressure and cardiovascular risk, cites average U.S. intake (~3,400 mg/day) versus recommended 1,500–2,300 mg, and notes CVD causes ~700,000 U.S. deaths annually. The program will produce patient and clinician resources to identify sodium exposures (food, beverages, medications) and encourage actionable sodium-reduction strategies for at-risk sleep-disorder populations.

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Jazz Pharmaceuticals (Nasdaq: JAZZ) announced seven presentations at AACR 2026 (April 17-22) highlighting clinical and preclinical progress across its oncology programs.

Key items include Phase 2 NeoZanHER results showing a 30% pathologic complete response (pCR) rate with zanidatamab at six weeks, mechanistic multi-omics on zanidatamab, preclinical JZP898 tumor-localized interferon activity, and imipridone (dordaviprone) combination studies.

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Jazz Pharmaceuticals (Nasdaq: JAZZ) reported record 2025 total revenue of $4.3 billion (up 5% YoY) and 4Q25 revenue of $1.2 billion (up 10% YoY). Key drivers included Xywav $1.7B (+12%), Epidiolex $1.1B (+9%), and Modeyso launch sales of $48M. GAAP net loss was $356M for 2025 with non-GAAP adjusted net income of $522M. Jazz expects 2026 total revenues of $4.25–$4.50 billion and plans an sBLA submission for zanidatamab under RTOR in 1Q26 with potential 1L HER2+ GEA launch in 2H26.

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Jazz Pharmaceuticals (Nasdaq: JAZZ) will participate in two investor conferences in March 2026: TD Cowen 46th Annual Health Care Conference on March 3, 2026 and Barclays 28th Annual Global Healthcare Conference on March 12, 2026.

Fireside chat times: March 3 at 7:30 a.m. PT / 10:30 a.m. ET / 2:30 p.m. GMT, and March 12 at 7:00 a.m. PT / 10:00 a.m. ET / 2:00 p.m. GMT. An audio webcast and a replay archived for 30 days will be available via the company's Investors website.

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Jazz Pharmaceuticals (Nasdaq: JAZZ) will report fourth quarter and full year 2025 financial results on February 24, 2026 after the close of U.S. markets. Management will host a live webcast at 4:30 p.m. ET / 9:30 p.m. GMT to discuss results and provide a business and financial update.

Interested parties may register in advance via the Investors section of the Jazz Pharmaceuticals website. A replay will be posted to the investor site for on‑demand access.

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Jazz Pharmaceuticals (Nasdaq: JAZZ) announced the appointment of Thomas Riga as Chief Business Officer, effective January 1, 2026. Mr. Riga joined Jazz in April 2025 through the acquisition of Chimerix and previously served as chief operating and commercial officer at Chimerix, where he directed corporate strategy and led the transaction that sold Chimerix to Jazz. He helped navigate the regulatory process for U.S. approval and launch of Modeyso (dordaviprone), the first approved therapy for H3K27M-mutant diffuse midline glioma. Management says Riga has 25+ years of industry experience and led over $2 billion in business development deals in the past five years.

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Jazz Pharmaceuticals (Nasdaq: JAZZ) reported positive Phase 3 HERIZON-GEA-01 results for Ziihera (zanidatamab-hrii) in first-line HER2+ locally advanced or metastatic GEA. Both Ziihera arms (with chemotherapy, and with tislelizumab plus chemotherapy) showed ~35% reduction in progression or death versus trastuzumab plus chemotherapy, with median PFS >1 year (~12.4 months vs 8.1 months).

The Ziihera+tislelizumab arm reached a median overall survival of 26.4 months (OS HR 0.72; P=0.0043), a >7-month improvement versus control; Ziihera+chemo showed median OS 24.4 months (OS HR 0.80; P=0.0564) with a strong positive trend. Safety was consistent with HER2 and immunotherapy profiles; higher Grade ≥3 TRAEs and diarrhea rates were reported with the combination including tislelizumab.

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Jazz Pharmaceuticals (Nasdaq: JAZZ) will host investor webcasts in January 2026 to review clinical and corporate updates.

Key events: a zanidatamab HERIZON-GEA-01 Phase 3 results webcast on Jan 9, 2026 at 6:30 a.m. PT / 3:30 p.m. GMT following the oral presentation at ASCO GI on Jan 8, 2026; and a corporate presentation by CEO Renee Gala at the J.P. Morgan Healthcare Conference on Jan 13, 2026 at 11:15 a.m. PST / 7:15 p.m. GMT.

Audio webcasts and 30-day replays will be available via the Investors section of Jazz Pharmaceuticals' website.

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Jazz Pharmaceuticals (Nasdaq: JAZZ) will present eight abstracts, including four late-breaking posters, on Epidiolex (cannabidiol) at the American Epilepsy Society 2025 meeting (Dec 5–9, 2025) in Atlanta.

Key findings include a 6-month intermediate EpiCom analysis showing reductions in TAND-SQ and ABC subscale scores and caregiver/clinician‑reported behavioral severity after 26 weeks of adjunctive Epidiolex in tuberous sclerosis complex; a Phase 1 PK study finding no pharmacokinetic interaction between Epidiolex and cenobamate; preclinical synergistic PD effects with cenobamate; and multiple real-world analyses reporting reduced polypharmacy, antiseizure‑medication cycling, healthcare resource utilization, and seizure frequency versus external control.

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FAQ

What is the current stock price of Jazz Pharmaceuticals (JAZZ)?

The current stock price of Jazz Pharmaceuticals (JAZZ) is $236.28 as of September 25, 2026.

What is the market cap of Jazz Pharmaceuticals (JAZZ)?

The market cap of Jazz Pharmaceuticals (JAZZ) is approximately 15.3B.