Welcome to our dedicated page for Jasper Therapeutics news (Ticker: JSPR), a resource for investors and traders seeking the latest updates and insights on Jasper Therapeutics stock.
Jasper Therapeutics, Inc. (Nasdaq: JSPR) is a clinical-stage biotechnology company focused on developing briquilimab, an aglycosylated monoclonal antibody targeting KIT (CD117) for chronic mast cell diseases such as chronic spontaneous urticaria (CSU), chronic inducible urticaria (CIndU) and asthma. The JSPR news feed highlights company announcements on clinical data, corporate developments and financing activities that shape the outlook for this mast cell–focused program.
News updates commonly cover clinical trial results and study updates. Jasper has reported data from the BEACON Phase 1b/2a study in CSU, an open-label extension study in chronic urticarias, and the ETESIAN Phase 1b/2a study in allergic asthma. These releases describe endpoints such as Urticaria Activity Score over 7 days (UAS7), hives and itch severity scores, airway hyperresponsiveness, sputum eosinophils, serum tryptase, and safety findings, including observations related to KIT blockade.
The JSPR news stream also includes corporate and strategic announcements, such as leadership changes, corporate reorganizations, and decisions to concentrate resources on briquilimab in mast cell driven diseases. Investors can find information on Jasper’s participation in healthcare and investor conferences, where management discusses briquilimab’s development and provides program updates.
In addition, Jasper issues financing and capital markets news, including details of public offerings of common stock, pre-funded warrants and common warrants, and stated uses of proceeds for advancing briquilimab and supporting general corporate purposes. Together, these news items provide context on clinical progress, strategic focus and funding for Jasper’s lead program. For readers tracking JSPR, this page offers a centralized view of the company’s press releases and related communications.
Jasper Therapeutics (Nasdaq: JSPR) reported positive data from its SPOTLIGHT Phase 1b/2a study of subcutaneous briquilimab in adults with chronic inducible urticaria (CIndU). Key findings include:
- 14 of 15 participants (93%) achieved a clinical response within 6 weeks
- In the 120mg dose cohort, 10 of 12 participants (83%) experienced a complete response
- No serious adverse events or grade 3+ adverse events reported
- Significant reductions in tryptase observed, correlating with clinical responses
The company plans to enroll a 180mg dose cohort and expects to present full data in the first half of 2025. Additionally, Jasper anticipates reporting initial data from all cohorts of the BEACON study in chronic spontaneous urticaria during the week of January 6th, 2025.
Jasper Therapeutics (Nasdaq: JSPR) announced Health Canada's clearance of its Clinical Trial Application for a Phase 1b/2a asthma challenge study evaluating briquilimab. The study, set to enroll 30 patients across Canada and the EU, aims to demonstrate proof-of-concept for mast cell depletion as an effective mechanism in asthma treatment. Key assessments include early and late asthmatic response, airway hyperresponsiveness changes, and mast cell depletion.
The company plans to begin dosing patients in Q4 2024 and report initial data in H2 2025. Additionally, Jasper received trademark approval for its proprietary Jasper c-Kit Mouse™ model, which enables direct testing of c-Kit inhibitors across various diseases, overcoming limitations of standard models.
Jasper Therapeutics (Nasdaq: JSPR), a biotech company developing briquilimab, a novel antibody therapy targeting c-Kit (CD117) for mast cell-driven diseases, has announced its participation in three upcoming investor conferences in September 2024:
1. H.C. Wainwright 26th Annual Global Investment Conference (Sept 9-11, fireside chat on Sept 10 at 3:00 p.m. ET)
2. 2024 Cantor Fitzgerald Healthcare Conference (Sept 17-19, fireside chat on Sept 17 at 2:30 p.m. ET)
3. TD Cowen Chronic Urticaria Summit (Sept 20, fireside chat at 12:00 p.m. ET)
Live webcasts of the presentations will be available on Jasper's Investor Relations website, with archived replays accessible for 30 days after the live broadcasts.
Jasper Therapeutics (Nasdaq: JSPR) reported Q2 2024 financial results and corporate updates. Key highlights include:
1. Faster-than-expected enrollment in BEACON and SPOTLIGHT studies for briquilimab in chronic urticaria.
2. Additional 180mg Q8W dosing cohort added to BEACON study.
3. Initial data from BEACON study (up to 240mg dosing) expected in Q4 2024.
4. Expanded mast cell portfolio with new asthma program.
5. Q2 2024 financials: $106.8M cash on hand, $11.3M R&D expenses, $4.7M G&A expenses, $15.0M net loss ($0.97 per share).
The company remains optimistic about briquilimab's potential in mast cell-driven diseases and plans to present initial data from both BEACON and SPOTLIGHT studies later this year.
Jasper Therapeutics (Nasdaq: JSPR), a clinical-stage biotech firm specializing in briquilimab, an antibody therapy for mast cell-driven diseases, announced the appointment of Svetlana Lucas, Ph.D., to its Board of Directors, effective June 18, 2024. Dr. Lucas brings over 20 years of experience in strategy, commercialization, and business development, notably in immunology and oncology. She has held key roles at Scribe Therapeutics, Tizona Therapeutics, and Amgen. Her appointment follows the departure of Anna French, a founding investor and Board member. Dr. Lucas expressed enthusiasm for contributing to Jasper's growth and the potential of briquilimab to address various diseases.
Jasper Therapeutics, a biotech firm, will present at the Oppenheimer Novel Targets in Immunology Summit on June 24, 2024, in New York City. The company specializes in briquilimab, an antibody therapy targeting c-Kit (CD117) to treat mast cell-driven diseases like chronic spontaneous urticaria (CSU), chronic inducible urticaria (CIndU), and asthma. The presentation, scheduled for 11:45 a.m. EDT, will be a panel discussion on 'Novel Immunological Mechanisms for Dermatologic Disorders'.
Jasper Therapeutics (Nasdaq: JSPR) presented preclinical data on briquilimab at the 2024 EHA Hybrid Congress in Madrid. This study focused on the impact of briquilimab, a novel antibody therapy targeting c-Kit (CD117), on hematopoietic stem cells (HSCs). The findings indicate that while briquilimab blocks SCF/c-Kit signaling, it does not cause apoptosis in healthy HSCs. Instead, it promotes HSC differentiation into CD34- cells with higher c-Kit expression but without increased CD38 expression. These results support briquilimab's safety profile for treating mast cell-driven diseases like chronic urticaria and asthma.
Jasper Therapeutics will present data on briquilimab at the EAACI Congress 2024 in Valencia, Spain from May 31 to June 3. Briquilimab, a novel antibody targeting c-Kit (CD117), aims to treat mast cell-driven diseases like asthma, chronic spontaneous urticaria (CSU), and chronic inducible urticaria (CIndU). Key findings include briquilimab's ability to deplete mast cells and improve lung function in asthma models, as well as reduce dermal mast cells and inflammatory leukocytes in atopic dermatitis (AD) models. A healthy volunteer study showed briquilimab is well-tolerated, with promising pharmacokinetic and pharmacodynamic profiles. The data supports ongoing BEACON and SPOTLIGHT trials in CSU and CIndU. Jasper plans to begin a Phase 1b/2a trial in asthma later in 2024.
Jasper Therapeutics (Nasdaq: JSPR) will present at the Jefferies Global Healthcare Conference on June 5, 2024, at 4:00pm EDT. The biotechnology company, focused on developing briquilimab for diseases like chronic spontaneous urticaria, chronic inducible urticaria, and asthma, will provide a live webcast of the presentation on their Investor Relations website. The presentation will also be archived for 30 days.
Jasper Therapeutics (Nasdaq: JSPR), a biotechnology company developing briquilimab for mast cell-driven diseases, announced its Q1 2024 financial results and corporate updates.
Key progress includes enrollment in Phase 1b/2a BEACON and SPOTLIGHT studies for chronic urticarias, with initial data expected in Q3 and H2 2024.
Jasper is also advancing briquilimab for asthma, starting enrollment in Q4 2024.
Financially, Jasper reported a net loss of $13.7 million, with cash reserves of $118.5 million, extending its runway through Q3 2025 after a $50 million stock offering in February 2024.
Other developments include positive data on briquilimab for CGD and MDS, and the issuance of inducement stock options to new employees.