Welcome to our dedicated page for Kiniksa Pharmaceuticals International, plc news (Ticker: KNSA), a resource for investors and traders seeking the latest updates and insights on Kiniksa Pharmaceuticals International, plc stock.
Kiniksa Pharmaceuticals International, plc (Nasdaq: KNSA) generates frequent news through its work as a biopharmaceutical company focused on cardiovascular indications and diseases with unmet need. Company press releases and Form 8‑K filings highlight developments around its IL‑1 pathway franchise, including the commercial performance of ARCALYST (rilonacept) and the clinical progress of investigational monoclonal antibodies KPL‑387 and KPL‑1161.
News items commonly cover quarterly and annual financial results, where Kiniksa reports ARCALYST net product revenue, trends in prescriber adoption, and changes in guidance for expected ARCALYST net product revenue. These updates often include commentary on the uptake of IL‑1α and IL‑1β inhibition in recurrent pericarditis, the proportion of multiple‑recurrence patients on ARCALYST therapy, and the average duration of treatment.
Investors following KNSA news also see regular clinical and regulatory milestones. Kiniksa has announced the initiation and design of a Phase 2/3 clinical trial of KPL‑387 in recurrent pericarditis, Phase 1 data supporting a monthly dosing profile, and the U.S. FDA’s Orphan Drug Designation for KPL‑387 for the treatment of pericarditis. Additional updates describe preclinical or IND‑enabling activities for KPL‑1161, which has a target profile of quarterly subcutaneous dosing.
Corporate and investor‑relations announcements form another key part of the KNSA news flow. The company frequently issues notices about upcoming and completed presentations at healthcare and investor conferences, such as the J.P. Morgan Healthcare Conference, Jefferies Global Healthcare Conference, and other biopharma‑focused events. These communications typically reference webcasts and replays available through Kiniksa’s investor channels.
By monitoring this news stream, readers can track how Kiniksa manages ARCALYST commercialization, advances its IL‑1R1‑targeted pipeline, and updates its financial outlook. The KNSA news page on Stock Titan aggregates these releases so investors and observers can review earnings announcements, trial updates, regulatory designations, and conference participation in one place.
Kiniksa Pharmaceuticals (KNSA) reported positive results from RHAPSODY, a pivotal Phase 3 trial of rilonacept for recurrent pericarditis. The trial met its primary and all major secondary efficacy endpoints, showing a 96% reduction in recurrence risk (Hazard Ratio = 0.04, p<0.0001). The safety profile aligns with FDA-approved uses for CAPS. Kiniksa plans to submit a Supplemental Biologics License Application (sBLA) later this year. Rilonacept is positioned to potentially become the first FDA-approved treatment for recurrent pericarditis, addressing significant unmet medical needs.
Kiniksa Pharmaceuticals (KNSA) announced a presentation at the European E-Congress of Rheumatology (EULAR) 2020 on June 3, 2020, showcasing data on mavrilimumab, an investigational monoclonal antibody for severe COVID-19 pneumonia and hyperinflammation. The oral presentation will detail outcomes from an open-label treatment protocol conducted in Italy, while additional preclinical data on the GM-CSF pathway in giant cell arteritis will be presented on June 5. Mavrilimumab has previously met its primary efficacy and safety endpoints in Phase 2b studies for rheumatoid arthritis.
Kiniksa Pharmaceuticals (KNSA) has closed a public offering of 2,760,000 Class A common shares at $18.25 each, raising approximately $80 million in gross proceeds. This includes the complete exercise of the underwriters' option to purchase additional shares. The offering was managed by Goldman Sachs, J.P. Morgan, and BofA Securities, with co-management by Wedbush Securities and JMP Securities. Kiniksa focuses on developing therapeutic medicines for serious diseases, with a clinical pipeline including rilonacept, mavrilimumab, vixarelimab, and KPL-404 targeting immunological pathways.
Kiniksa Pharmaceuticals (Nasdaq: KNSA) has announced a public offering of 2,400,000 Class A common shares, priced at $18.25 each, alongside a private placement of 1,600,000 shares. The total expected gross proceeds from both offerings is approximately $73 million. The funds will be used to advance clinical development and for general corporate purposes. The public offering is set to close on May 18, 2020, subject to standard conditions. The underwriters have a 30-day option to purchase an additional 360,000 shares.
Kiniksa Pharmaceuticals (Nasdaq: KNSA) announced a public offering of 1,800,000 Class A common shares, with an additional 270,000 shares available to underwriters. The net proceeds will support the clinical development of its product candidates, fund R&D activities, and cover general corporate purposes. Goldman Sachs, J.P. Morgan, and BofA Securities are managing the offering. Kiniksa emphasizes that the offering's details are included in the SEC registration statement, which should be reviewed before investing.
The press release from Kiniksa Pharmaceuticals, Ltd. highlights positive clinical results from two investigational treatments: mavrilimumab and vixarelimab. Mavrilimumab demonstrated improved outcomes in severe COVID-19 pneumonia patients, with 85% achieving clinical improvement by day 14, significantly outperforming the control group. Vixarelimab showed promising efficacy in chronic pruritus diseases, particularly plaque psoriasis, achieving a statistically significant reduction in itch severity. Kiniksa plans further development for both drugs, including potential registrational studies for mavrilimumab.
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