Kezar Life Sciences Stock Price, News & Analysis

Kezar Life Sciences announced the grant of stock options to its newly appointed Chief Business Officer, Nick Mordwinkin, totaling 200,000 shares at an exercise price of $9.35, equal to the stock's closing price on August 1, 2022. An additional employee received 60,000 shares under similar conditions. The options will vest over four years, contingent upon continued employment. This move aligns with Nasdaq Listing Rule 5635(c)(4), aimed at incentivizing key personnel. Kezar focuses on treatments for immune-mediated and oncologic disorders, advancing candidates like Zetomipzomib and KZR-261.

Kezar Life Sciences (NASDAQ: KZR) announced the appointment of Nick Mordwinkin, Pharm.D., Ph.D., as Chief Business Officer. Dr. Mordwinkin brings over a decade of experience in healthcare, previously at Gilead Sciences and Ultragenyx Pharmaceutical. His expertise will shape Kezar's business development strategy as the company advances its lead candidates, zetomipzomib and KZR-261. Additionally, Kezar reported an unaudited cash position of approximately $307 million as of June 30, 2022, positioning it well for future growth.

Kezar Life Sciences, a clinical-stage biotechnology company, announced that Dr. Noreen Roth Henig, Chief Medical Officer, will participate in a panel at the William Blair Biotech Focus Conference in New York on July 13, 2022, at 11:00 am ET. The panel will discuss developing therapies against novel targets in autoimmune diseases. Kezar is focused on breakthrough treatments for immune-mediated and oncologic disorders, with its lead asset, Zetomipzomib, currently in Phase 2 trials for lupus nephritis.

Kezar Life Sciences announced the grant of nonqualified stock options to three employees, covering a total of 24,500 shares at an exercise price of $9.29 per share, aligned with the stock's closing price on July 1, 2022. These options are part of the company’s 2022 Inducement Plan and will vest over four years, with 25% vesting after the first year. Kezar focuses on breakthrough treatments for immune-mediated and oncologic disorders, including a Phase 2 trial for Zetomipzomib in lupus nephritis and a Phase 1 trial for KZR-261 targeting solid tumors.

Kezar Life Sciences (NASDAQ: KZR) announced positive topline results from the MISSION Phase 2 clinical trial of zetomipzomib, a selective immunoproteasome inhibitor for lupus nephritis (LN). Out of 17 patients, 64.7% achieved a significant renal response, with 35.2% attaining complete renal response. The treatment demonstrated a favorable safety profile, reducing prednisone usage significantly. Improvements were also noted in extra-renal disease activity associated with systemic lupus erythematosus (SLE). A conference call to discuss these results is scheduled for today at 4:30 p.m. ET.

Kezar Life Sciences, Inc. (NASDAQ: KZR) announced the granting of nonqualified stock options to three employees, enabling them to purchase 12,000 shares at an exercise price of $4.86 per share, which matches the stock's closing price on June 1, 2022. The options will vest over four years, providing incentives for continued employment. This move adheres to Nasdaq Listing Rule 5635(c)(4) as an inducement for new hires.

Kezar Life Sciences reported its Q1 2022 financial results and business updates, highlighting a cash reserve of $242.6 million as of March 31, 2022. The company is preparing to release topline data from the Phase 2 MISSION trial for zetomipzomib in lupus nephritis in June 2022. KZR-261 is currently enrolling patients in a Phase 1 trial for solid tumors. However, the company experienced a net loss of $16.0 million, increasing from $13.0 million in the previous year, reflecting rising operational costs.

Kezar Life Sciences announced the granting of nonqualified stock options for 29,000 shares to two employees, with an exercise price of $12.54 per share, corresponding to its closing price on May 2, 2022. These options will vest over four years, starting with 25% after one year and the remainder vesting monthly. This move follows Nasdaq Listing Rule 5635(c)(4) and is part of Kezar's strategy to attract talent while continuing to develop therapies for immune-mediated and oncologic disorders.

Kezar Life Sciences announced topline results from the PRESIDIO Phase 2 trial of zetomipzomib (KZR-616) in patients with dermatomyositis and polymyositis. While most patients showed improvements in the Total Improvement Score, there was no significant differentiation from the placebo group. The drug demonstrated a favorable safety profile, with mild-to-moderate adverse events. Cash reserves stand at approximately $253 million as of April 30, 2022. Results from the ongoing MISSION Phase 2 trial in lupus nephritis are expected in June 2022, maintaining optimism for the drug’s potential.