Lineage Cell The Stock Price, News & Analysis

Lineage Cell Therapeutics announced statistically significant interim results from its Phase 1/2a study of OpRegen for treating dry age-related macular degeneration (AMD). After 9 to 15 months of follow-up, patients receiving OpRegen showed improved visual acuity compared to untreated eyes, with p-values indicating significance (P = 0.0085 at 9 months). The therapy was well tolerated, with no new adverse effects reported. The results suggest potential for OpRegen to address unmet needs in AMD treatment.

Lineage Cell Therapeutics, a clinical-stage biotechnology firm focused on allogeneic cell therapies, announced that CEO Brian M. Culley will present at the 2021 Cantor Fitzgerald Virtual Global Healthcare Conference on September 27 at 4pm ET. Interested parties can register for both live and on-demand presentations on the company's website. Lineage is developing three main products: OpRegen, OPC1, and VAC2, targeting significant health issues like dry age-related macular degeneration and non-small cell lung cancer.

Lineage Cell Therapeutics reported interim results from its Phase 1/2a study of OpRegen, a cell therapy for dry age-related macular degeneration (AMD). Key findings include:

• Zero growth of retinal atrophy in one patient after 33 months.
• 10% reduction in atrophy size noted at 8 months in another patient.
• Average visual acuity improvement of 10.8 letters in treated versus untreated eyes.

OpRegen has shown strong tolerability with no unexpected adverse events, suggesting potential for significant therapeutic outcomes.

Lineage Cell Therapeutics (LCTX) announced updated interim results from its Phase 1/2a study of OpRegen®, a cell therapy targeting dry age-related macular degeneration (AMD). The therapy aims to improve vision in patients with geographic atrophy. A podium presentation is scheduled for September 30, 2021, at the 54th Annual Scientific Meeting of the Retina Society in Chicago. The study includes a total of 24 patients, and the upcoming interim results will provide follow-up data for all treated patients, particularly focusing on Cohort 4, which showed better baseline vision.

Lineage Cell Therapeutics has appointed George A. Samuel III as its new General Counsel and Corporate Secretary. With nearly 15 years in corporate and transactional law, his background includes roles at Lytx and Cardiff Oncology, where he handled legal operations and compliance. The company anticipates Samuel's expertise will support its clinical development efforts and business partnerships, particularly for its OpRegen, OPC1, and VAC2 programs, which target significant medical needs and market opportunities.

Lineage Cell Therapeutics (NYSE: LCTX) reported Q2 2021 results, highlighting significant advancements in its clinical programs, particularly OpRegen for dry-AMD. Notably, 83% of patients exhibited stable or improved visual acuity six months post-treatment. The company is also reacquiring OPC1 for clinical trials, aided by a robust cash position of $68.7 million. Total revenue increased to $0.5 million due to new licensing agreements, despite a net loss of $4.8 million. Lineage's inclusion in the Russell 3000® Index is expected to enhance visibility.

Lineage Cell Therapeutics, Inc. (NYSE American and TASE: LCTX) announced that CEO Brian M. Culley will present at the H.C. Wainwright & Co. Inc. Virtual Ophthalmology Conference on August 17, 2021. The presentation will be available on-demand starting at 7am ET, and Mr. Culley will also join a panel discussion on addressing unmet medical needs in macular degeneration at 11am ET. Interested viewers can register for these presentations on the company's website, which also offers additional media resources.

Lineage Cell Therapeutics (NYSE American and TASE: LCTX) will release its second quarter 2021 financial and operating results on August 12, 2021. Following market closure, management will host a conference call at 4:30 p.m. ET to discuss the results and offer a business update. Interested individuals can join by phone or access a live webcast on Lineage's investor relations page. Lineage is focused on developing allogeneic cell therapies for unmet medical needs, with three key product candidates in various stages of clinical development targeting significant markets.

Lineage Cell Therapeutics (LCTX) has reported promising interim results from its ongoing Phase 1/2a clinical study of OpRegen, aimed at treating dry age-related macular degeneration (AMD). In Cohort 4, 83% of treated eyes maintained or improved visual acuity, with gains reaching +19 letters on the ETDRS chart. Treatments indicated anatomical restoration and durability, with some patients showing no progression of geographic atrophy for almost three years. The company plans to discuss future clinical development steps with the FDA later this year, positioning OpRegen as a leading option for AMD treatment.