Welcome to our dedicated page for Lineage Cell The news (Ticker: LCTX), a resource for investors and traders seeking the latest updates and insights on Lineage Cell The stock.
Lineage Cell Therapeutics, Inc. (LCTX) generates a steady flow of news as a clinical-stage biotechnology company developing allogeneic, or “off the shelf,” cell therapies for serious medical conditions. News updates commonly highlight progress across its proprietary cell-based technology platform, clinical programs, manufacturing capabilities, and strategic collaborations.
Investors following LCTX news can expect coverage of clinical milestones from its lead programs, including OpRegen retinal pigment epithelial cell therapy for geographic atrophy secondary to age-related macular degeneration and OPC1 oligodendrocyte progenitor cell therapy for spinal cord injuries. Company announcements often describe data presentations from ongoing studies, such as long-term follow-up results from the OpRegen Phase 1/2a trial and updates from the GAlette Phase 2a study, as well as developments in the DOSED clinical study evaluating a novel delivery system for OPC1 in subacute and chronic spinal cord injury.
Lineage’s news flow also features preclinical and platform updates, including progress with ReSonance (ANP1), an auditory neuronal progenitor cell program for hearing loss under a research collaboration with William Demant Invest A/S, and initiatives such as PNC1 for potential treatment of vision loss and ILT1, an islet cell transplant program for Type 1 Diabetes. Additional releases may cover advances in its AlloSCOPE manufacturing platform, cGMP production runs from its two-tiered cell banking system, and gene-editing collaborations involving the RND1 hypoimmune induced pluripotent stem cell line.
Corporate news items include quarterly financial results, capital-raising transactions, and governance matters disclosed through press releases and SEC filings. For investors and observers interested in the evolution of allogeneic cell transplantation, the LCTX news page provides ongoing insight into Lineage’s clinical data, research collaborations, manufacturing achievements, and strategic direction.
Lineage Cell Therapeutics (NYSE American: LCTX) has appointed Dr. Dipti Amin to its Board of Directors as of April 20, 2021. Dr. Amin, a seasoned Non-Executive Director with over 26 years in the pharmaceutical sector, brings extensive experience in clinical research, drug development, and compliance. The company’s Chairman, Al Kingsley, emphasized her ability to significantly advance Lineage’s mission to lead in allogeneic cell transplants. Dr. Amin expressed her enthusiasm about contributing to the company’s growth and guiding its product candidates towards later-stage clinical trials.
Lineage Cell Therapeutics (LCTX) announced a global licensing and collaboration agreement with Immunomic Therapeutics (ITI) to develop a new product candidate aimed at treating glioblastoma multiforme (GBM). This partnership will utilize Lineage's VAC cancer immunotherapy platform and ITI's proprietary Tumor Associated Antigen. Lineage will receive an upfront payment of $2 million and could earn up to $67 million in development and commercial milestones, plus royalties of up to 10% on future sales. This collaboration is expected to diversify Lineage's oncology pipeline and enhance its therapeutic offerings.
Lineage Cell Therapeutics (NYSE: LCTX) announced updated interim results from a Phase 1/2a study of OpRegen®, a cell therapy aimed at treating dry age-related macular degeneration (AMD). The study enrolled 24 patients in four cohorts, assessing safety, tolerability, and preliminary efficacy. Notably, Cohort 4 utilized a new 'thaw-and-inject' formulation, enhancing logistical efficiency. Results will be presented at the 2021 ARVO Annual Meeting on May 6, 2021. Dry AMD affects 85-90% of AMD cases, and no FDA-approved treatments currently exist for this condition.
Lineage Cell Therapeutics (NYSE American: LCTX) announced the compassionate use treatment of a patient with adult-onset vitelliform macular dystrophy (AVMD) using its cell therapy product, OpRegen, at Hadassah-Hebrew University Medical Center. This treatment follows approval from the Israeli Ministry of Health and aims to address the underlying retinal cell damage related to the disease. OpRegen, currently in a Phase 1/2a trial for dry age-related macular degeneration, employs allogeneic retinal pigment epithelium cells. The patient remains under follow-up care post-treatment.
Lineage Cell Therapeutics (NYSE American: LCTX) announced positive interim results from its Phase 1/2a clinical study of OpRegen, a cell therapy for dry age-related macular degeneration (AMD) with geographic atrophy (GA). In Cohort 4, 75% of patients showed maintained or improved visual acuity, with enhancements of up to +19 letters on an EDTRS chart. Notably, OpRegen has exhibited durability, with some patients demonstrating stable outcomes after over 5 years. The study utilized minimal immunosuppression, with no unexpected adverse events reported, suggesting potential for effective long-term treatment.
Lineage Cell Therapeutics (NYSE American and TASE: LCTX) announced that CEO Brian M. Culley will present at the Benzinga Global Biotech Small Cap conference on March 24, 2021, at 11:50 AM ET. He will also participate in a panel discussion titled “Coming Together to Address Unmet Medical Needs” at 12:50 PM ET. Investors can register for the event in advance at Benzinga's website. The event's webcasts will be accessible on Lineage's Events and Presentations page.
Lineage Cell Therapeutics (LCTX) announced its fourth quarter and full year 2020 financial results, highlighting significant clinical and operational milestones. Total revenues decreased to $1.8 million for 2020, down from $3.5 million in 2019. Operating expenses were $27.9 million, a reduction of $14.1 million year-over-year. The net loss for 2020 was $20.6 million, or $0.14 per share. Importantly, Lineage secured $35.9 million in new capital, strengthening its financial position. The company aims to continue advancing its pipeline with key FDA meetings and clinical data presentations planned for 2021.
Lineage Cell Therapeutics, Inc. (LCTX) has raised $36 million through liquidating marketable securities and an at-the-market offering to fund operations through 2023. The company reported $57 million in cash and cash equivalents as of March 5, 2021. CEO Brian Culley emphasized value creation via these sales and advancing product candidates. Lineage's strong balance sheet provides flexibility for partnership discussions. Additionally, it has realized $32.5 million from OncoCyte share sales, holding shares currently valued at around $4.2 million.
Lineage Cell Therapeutics (LCTX), a clinical-stage biotechnology firm, will announce its Q4 and full-year 2020 financial results on March 11, 2021, after U.S. market close. A conference call at 4:30 PM ET will follow, discussing these results and providing a business update. Known for its proprietary cell-based therapy platform, Lineage is advancing three allogeneic product candidates, including therapies for dry age-related macular degeneration and spinal cord injuries. The company aims to address significant medical needs in billion-dollar markets.
Lineage Cell Therapeutics (NYSE American and TASE: LCTX) announced that CEO Brian M. Culley will present at the Raymond James 42nd Annual Institutional Investors Conference on March 1, 2021, at 11:40 AM Eastern Time. He will also present at the H.C. Wainwright Global Life Sciences Conference on March 9-10, 2021. Investors can access live and archived webcasts of these events on Lineage's Events and Presentations page.