Welcome to our dedicated page for Lineage Cell Therapeutics news (Ticker: LCTX), a resource for investors and traders seeking the latest updates and insights on Lineage Cell Therapeutics stock.
Lineage Cell Therapeutics, Inc. develops allogeneic, or “off-the-shelf,” cell therapies for serious medical conditions using its AlloSCOPE cell differentiation and expansion platform. Its pipeline includes OpRegen, also known as RG6501, for geographic atrophy secondary to age-related macular degeneration; OPC1 for spinal cord injury; ReSonance, or ANP1, for hearing loss; and COR1 for corneal endothelial disease.
Recurring company news covers clinical data presentations, preclinical program launches, manufacturing and platform updates, research collaborations, milestone activity, financial results, business updates, and scientific governance. Updates frequently connect Lineage’s cell transplant programs with ophthalmology, neurology, auditory disease, and other non-oncology therapeutic areas.
Lineage Cell Therapeutics (LCTX) reported its Q4 and full year 2024 financial results, highlighting significant progress across multiple programs. The company's lead asset OpRegen, developed in collaboration with Roche and Genentech, received RMAT designation from FDA for geographic atrophy treatment.
Financial highlights include:
- Q4 2024 revenues of $2.9M (up from $2.1M in Q4 2023)
- Full year 2024 revenues of $9.5M (up from $8.9M in 2023)
- Q4 net loss of $3.3M ($0.02 per share)
- Full year net loss of $18.6M ($0.09 per share)
- Cash position of $47.8M as of December 31, 2024
The company completed two financings totaling $44M in gross proceeds, with potential for additional $36M from warrant exercises. Current cash runway extends into Q1 2027. Operating expenses decreased to $31.0M in 2024 from $33.7M in 2023, reflecting improved operational efficiency.
Lineage Cell Therapeutics (NYSE American and TASE: LCTX), a clinical-stage biotechnology company focused on allogeneic cell therapies for neurological conditions, has scheduled its fourth quarter and full year 2024 financial results announcement for March 10, 2025, after U.S. market close.
The company will host a conference call and webcast at 4:30 p.m. Eastern Time/1:30 p.m. Pacific Time on the same day. Investors can join via phone at (800) 715-9871 from the U.S. and Canada, requesting the 'Lineage Cell Therapeutics Call'. A webcast will be available in the Investors section of the company's website, with replay access through March 17th, 2025 (conference ID: 6707203).
Lineage Cell Therapeutics (NYSE: LCTX) has initiated the DOSED clinical study to evaluate a novel delivery device for OPC1, their investigational stem cell-derived transplant for spinal cord injury (SCI). The study will assess the safety and utility of the Manual Inject Parenchymal Spinal Delivery System (MI PSD System) for delivering OPC1 to injury sites.
The DOSED study will include both subacute (21-42 days post-injury) and chronic (1-5 years post-injury) SCI patients, marking the first time OPC1 will be tested in chronic cases. OPC1 has already demonstrated a strong safety profile in two previous clinical trials: a five-patient Phase 1 safety trial in acute thoracic SCI with 13+ years of follow-up, and a 25-patient Phase 1/2a trial in subacute cervical SCI with 7+ years of follow-up.
The new delivery system allows administration over several minutes without interrupting patient ventilation and is compatible with a new immediate-use formulation of OPC1. The first study site will be UC San Diego Health.
Lineage Cell Therapeutics (NYSE American and TASE: LCTX), a clinical-stage biotechnology company focused on developing allogeneic cell therapies for neurological conditions, has announced its participation in the upcoming Oppenheimer 35th Annual Healthcare Lifesciences Conference.
The company's CEO, Brian M. Culley, is scheduled to present on February 11, 2025, at 12:40pm ET. The conference will be held virtually from February 11-12, 2025. Interested parties will be able to access a replay of the presentation through the Events and Presentations section of Lineage's website, with additional video content available on the company's Media page.
Lineage Cell Therapeutics (NYSE: LCTX) has completed the second tranche of its previously announced registered direct offering, receiving an additional $6 million in gross proceeds. This follows the first tranche closure in November 2024, which brought in $24 million. The total gross proceeds received now stand at $30 million.
The company could receive up to an additional $36 million upon full exercise of OpRegen® clinical milestone-linked warrants. The second tranche involved issuing 7,894,737 common shares with accompanying warrants to Broadwood Partners at $0.76 per share. The warrants are exercisable at $0.91 per share starting May 21, 2025, expiring on May 21, 2028, or 90 days after announcing intent to advance OpRegen into a phase 2 or 3 clinical trial.
Lineage Cell Therapeutics (NYSE American and TASE: LCTX), a clinical-stage biotech firm developing allogeneic cell therapies, has published a letter to shareholders detailing recent achievements and its 2025 outlook. Lineage specializes in cell transplants, using mature, differentiated cells to replace lost or dysfunctional cells in conditions like dry age-related macular degeneration (dry-AMD). Their lead program, OpRegen, is in a Phase 2a trial in partnership with Roche and Genentech.
Lineage's financing strategy has secured $24 million in gross proceeds with an additional $6 million expected, extending their operational runway into Q1 2027. They have also issued warrants for up to $36 million, contingent on OpRegen’s advancement. The company aims to demonstrate scalable manufacturing capabilities, aspiring to produce thousands of doses from a single donor.
Looking ahead, Lineage plans to support OpRegen’s development while advancing its other programs, including OPC1 for spinal cord injuries and ReSonance™ for hearing loss. The company emphasizes its potential for long-term value creation through its unique cell transplant approach.
Lineage Cell Therapeutics (LCTX) announced the first closing of a registered direct offering of up to $66 million. The company issued 31,578,951 common shares and warrants at $0.76 per share to healthcare-focused institutional investors, receiving $24 million in gross proceeds. An additional $6 million is expected from Broadwood Partners pending shareholder approval. The warrants, exercisable at $0.91 per share, could provide up to $36 million in additional proceeds if fully exercised. The funds will be used for working capital, research and development, and capital expenditures.
Lineage Cell Therapeutics (NYSE: LCTX) has announced a registered direct offering of up to $66 million through the sale of 39,473,688 common shares and warrants. The offering includes $30 million upfront ($24 million from institutional investors and $6 million from Broadwood Partners) at $0.76 per share-warrant combination. Additional proceeds of up to $36 million may come from warrant exercises at $0.91 per share. The warrants are exercisable after six months and expire within three years or 90 days after OpRegen's Phase 2/3 trial announcement. The offering to institutional investors should close around November 21, 2024, while Broadwood's portion requires shareholder approval.
Lineage Cell Therapeutics (LCTX) reported Q3 2024 financial results with revenues of $3.8 million, up from $1.2 million in Q3 2023. The company posted a net loss of $3.0 million ($0.02 per share), improved from $7.1 million loss year-over-year. Operating expenses decreased to $7.6 million from $7.9 million. Cash position of $32.7 million is expected to fund operations into Q1 2026.
Key highlights include OpRegen receiving RMAT designation from FDA, continued collaboration with Roche/Genentech, and presentation of ReSonance preclinical results at the Inner Ear Biology Workshop.
Lineage Cell Therapeutics (NYSE American and TASE: LCTX) has scheduled its third quarter 2024 financial results announcement and business update for November 14, 2024, after U.S. market close. The company will host a conference call and webcast at 4:30 p.m. Eastern Time/1:30 p.m. Pacific Time on the same day. Investors can join via phone at (800) 715-9871 or through the company's website. A replay will be available online for 30 days and by phone until November 21, 2024, using conference ID 2238934.