Longeveron Inc Stock Price, News & Analysis

Longeveron Inc. (NASDAQ: LGVN) reported favorable outcomes from its Phase 2b trial of Lomecel-B, a therapy aimed at addressing Aging Frailty. At Day 180, patients receiving higher doses (50M, 100M, 200M) exhibited a statistically significant increase in six-minute walk test distances compared to placebo. While pairwise comparisons to placebo did not achieve significance, exploratory results at Day 270 indicated notable improvements. Longeveron plans to advance its research and discuss findings with regulatory authorities, as no serious adverse events were reported, maintaining a positive safety profile for Lomecel-B.

Longeveron Inc. (NASDAQ: LGVN) reported its Q2 2021 financial results, revealing a revenue decline to $0.5 million from $0.9 million year-over-year, primarily due to reduced grant revenue. The company achieved statistically significant results in its Phase 2b Aging Frailty trial for Lomecel-B, but did not meet primary efficacy endpoints at Day 180 compared to placebo. R&D expenses rose 205% to $2.0 million, contributing to a net loss of $5.0 million. However, cash reserves increased significantly to $16.8 million, providing runway through Q4 2022. A conference call is scheduled for today at 8:00 AM EDT.

Longeveron Inc. (NASDAQ: LGVN) announced it will release its second quarter 2021 financial results on August 13, 2021, before US market opening. Management will host a conference call at 8:00 AM to discuss these results. The call can be accessed via multiple phone lines and will be available for replay until August 19, 2021. Longeveron is focused on developing cellular therapies for chronic and life-threatening aging-related conditions, with its lead product, LOMECEL-B™, currently in Phase 1 and 2 clinical trials targeting several serious medical issues.

Longeveron Inc. (NASDAQ: LGVN) has announced the enrollment of the first patient in a Phase 2b clinical trial for Lomecel-B, aimed at infants with Hypoplastic Left Heart Syndrome (HLHS). Funded by the National Heart, Lung, and Blood Institute, this double-blind study will assess the safety and efficacy of the investigational MSC product. With a target enrollment of 38 infants across seven U.S. children's hospitals, the trial builds upon the successful Phase 1 results, which reported no major adverse events. The study aims to improve heart function post-surgery in HLHS patients.

Longeveron Inc. (NASDAQ: LGVN) announced that two abstracts for its investigational cell therapy, Lomecel-B, have been accepted for presentation at the Gerontological Society of America (GSA) 2021 Annual Scientific Meeting, scheduled for November 10-14, 2021, in Phoenix, AZ. The abstracts include:

• A Phase 2b Clinical Trial Assessing Lomecel-B Infusion in Individuals with Aging Frailty
• A Phase 1 Trial Assessing Lomecel-B Infusion in Individuals with Alzheimer’s Disease

This indicates ongoing progress in clinical trials aimed at addressing aging-related conditions.

Longeveron Inc. (NASDAQ: LGVN) announced the acceptance of an abstract for a poster presentation at the 2021 Annual Alzheimer's Association International Conference. This presentation highlights the results of their Phase 1 trial on Lomecel-B infusion in patients with mild Alzheimer’s disease. The trial met its primary endpoint of safety and feasibility, showing no Alzheimer’s Related Imaging Abnormalities (ARIA). Additionally, low-dose Lomecel-B demonstrated a reduction in cognitive decline compared to placebo, measured by the Mini Mental State Exam (MMSE). A Phase 2 trial is anticipated in the second half of 2021.

Longeveron Inc. (NASDAQ: LGVN), a clinical stage biotechnology firm, announced that CEO Geoff Green will present virtually at the World Stem Cell Summit on June 17, 2021, at 9:45 AM EDT. The 20-minute presentation will cover a corporate overview and research updates, followed by a 20-minute Q&A session. Interested participants can register for the event via the World Stem Cell Summit and the Investor Forum. Longeveron focuses on developing cellular therapies for aging-related and life-threatening conditions, with its lead product Lomecel-B currently in clinical trials for multiple indications.

Longeveron Inc. (NASDAQ: LGVN) announced that its Co-founder and Chairman, Dr. Joshua M. Hare, will be a panelist at the National Academy of Medicine’s workshop on June 15, 2021. The symposium, titled “Transformative Advances in Biological Sciences for Healthy Longevity,” aims to develop a Global Roadmap for Healthy Longevity. Longeveron is focused on cell-based therapies for aging-related diseases, with ongoing clinical trials for its lead product, Lomecel-B, targeting aging frailty and Alzheimer’s disease. Top-line data from recent trials is expected in Q3 2021.

Longeveron (NASDAQ: LGVN) announced the appointment of Ursula Ungaro to its Board of Directors, effective June 1, 2021. Ungaro, who has served on the U.S. District Court for the Southern District of Florida since 1992, brings extensive legal experience, particularly in civil and securities law. Her retirement from the judiciary was motivated by her desire to contribute to Longeveron's growth in cellular therapies, including the development of Lomecel-B for aging-related conditions. CEO Geoff Green expressed confidence in her ability to guide the company's clinical advancements and commercialization efforts.