Welcome to our dedicated page for Lixte Biotechnology Hldgs news (Ticker: LIXT), a resource for investors and traders seeking the latest updates and insights on Lixte Biotechnology Hldgs stock.
Lixte Biotechnology Holdings, Inc. (NASDAQ: LIXT) is a clinical-stage pharmaceutical company focused on cancer drug development, with news flow that reflects both its scientific programs and corporate strategy. Company announcements emphasize its lead compound LB-100, a first-in-class PP2A inhibitor, and its efforts to develop and commercialize cancer therapies targeting solid tumors with unmet medical needs.
News about Lixte often highlights clinical trial progress for LB-100, including proof-of-concept studies in ovarian clear cell carcinoma, metastatic colon cancer, and advanced soft tissue sarcoma. Releases describe collaborations with major institutions such as The University of Texas MD Anderson Cancer Center and the Robert H. Lurie Comprehensive Cancer Center of Northwestern University, as well as partnerships with large pharmaceutical companies supplying immunotherapies for combination studies.
Investors following LIXT can also expect updates on strategic transactions and platform expansion. Recent news includes the acquisition of Liora Technologies Europe Ltd., which holds the LiGHT System, an electronically controlled proton therapy platform. This transaction marks Lixte’s entry into the radiotherapy segment of cancer care and is presented as a complement to its LB-100 program.
In addition, Lixte issues releases on capital raises, such as registered direct offerings and private placements, as well as governance and proxy matters described in its definitive proxy statement. For investors and observers, the LIXT news stream provides insight into how the company is advancing LB-100, building a multi-asset oncology platform, managing its capital structure, and executing on its stated mission in oncology.
LIXTE Biotechnology (Nasdaq: LIXT) is the sponsor of the inaugural Good Health: Mind, Body & Soul Summit led by De La Soul on February 19, 2026 at Morehouse College in Atlanta. The invitation-only event convenes health experts, artists, athletes, researchers, and advocates to advance health equity for Black men and families. Programming covers cancer, heart disease, mental health, addiction, sleep, relationships, and intergenerational wellness, linking science and lived experience. Attendance is by invitation; more information is available at the summit website.
LIXTE Biotechnology (Nasdaq: LIXT) will participate at the DealFlow Discovery Conference in Atlantic City, New Jersey on January 28-29, 2026. CEO Geordan Pursglove is scheduled to hold one-on-one investor meetings at The Borgata Hotel, Casino & Spa. The company is clinical-stage and advancing LB-100, a PP2A inhibitor. Investors may register or request meetings via the conference registration page.
LIXTE (Nasdaq: LIXT) announced an expansion of its ongoing ovarian clear cell cancer trial combining its compound LB-100 with GSK's dostarlimab. The study, initiated in January 2024, will double enrollment from 21 to 42 patients across two sites: MD Anderson and the Robert H. Lurie Comprehensive Cancer Center at Northwestern. The trial is led by Amir Jazaeri, MD, and Emily M. Hinchcliff, MD, MPH. LIXTE expects initial data from the first 21 patients to be presented in the first half of 2026. The company framed the expansion as progress toward evaluating LB-100’s potential to enhance immunotherapy and chemotherapy outcomes.
Lixte Biotechnology (NASDAQ: LIXT) entered definitive agreements for a registered direct offering to raise approximately $4.3 million by selling 1,051,342 Common Units (or Pre-Funded Units) at a public offering price of $4.09 per Common Unit (or $4.08999 per Pre-Funded Unit). Each unit includes one share or one pre-funded warrant plus one common warrant exercisable at $3.96 and expiring 60 months after issuance. Pre-Funded Warrants are immediately exercisable. The offering is priced at the market under Nasdaq rules and is expected to close on or about December 19, 2025. Proceeds are intended for general corporate purposes and working capital.
Spartan Capital Securities is exclusive placement agent; offering made from an effective Form S-3 shelf (declared effective May 2, 2024).
LIXTE (NASDAQ:LIXT) is broadening its oncology strategy by acquiring Liora Technologies and adding the LiGHT System radiotherapy platform, signaling a shift from a single‑asset biotech toward a multi‑modal oncology company.
The move (announced December 8, 2025) pairs LIXTE's clinical‑stage drug LB‑100—a PP2A inhibitor that sensitizes tumors to stress—with a smaller‑footprint proton radiotherapy system, enabling potential drug‑device combinations and more direct clinical evaluation.
LIXTE (NASDAQ:LIXT) is advancing its lead clinical-stage PP2A inhibitor LB-100 and shifting toward a multi-modal oncology platform as of December 3, 2025. Key developments include active collaborations testing LB-100 with dostarlimab (GSK) and atezolizumab (Roche), a temporary safety pause in the metastatic microsatellite-stable colon-cancer combo trial, and prior Phase 1 tolerability data in soft-tissue sarcoma. Strategically, LIXTE announced the acquisition of Liora Technologies Europe Ltd. (LiGHT proton therapy system) and reported converting about $2.6 million of treasury into digital/convertible assets, part of talks to acquire complementary oncology assets to broaden its pipeline.
Those moves expand LIXTE from a single‑asset biotech toward a diversified science and infrastructure strategy combining drugs, radiation hardware, and balance-sheet flexibility.
LIXTE Biotechnology (NASDAQ:LIXT) on December 3, 2025 outlined progress for its PP2A inhibitor LB-100, positioning the drug as an "amplifier" to boost chemo, radiation, and immunotherapy.
Key points: Phase 1 tolerability reported with no toxicity concerns; partnerships with GSK (dostarlimab, full funding for ovarian program) and Roche (atezolizumab, full funding for colorectal study); enrollment finished in a Phase 1b soft-tissue sarcoma trial but further development there is paused to focus on combinations. Company also restored Nasdaq compliance and added digital assets to its treasury.
LIXTE Biotechnology (Nasdaq: LIXT) completed the acquisition of UK-based Liora Technologies Europe Ltd. on November 25, 2025, making Liora a wholly owned subsidiary and adding the proprietary LiGHT System (Linac for Image Guided Hadron Therapy) to LIXTE’s assets.
The LiGHT System is installed at STFC’s Daresbury Laboratory, where STFC will provide resources to develop a center of excellence. The release notes $300+ million invested to date in developing the technology and describes LIXTE’s plan to pursue a recurring revenue model through jointly operated treatment centers while complementing ongoing LB-100 clinical trials.
LIXTE Biotechnology Holdings (Nasdaq: LIXT) announced that CEO Geordan Pursglove will present at the Spartan Capital Investor Conference 2025 in New York on November 3, 2025 at 4:00 PM ET. Management will also hold one-on-one investor meetings during the conference.
The event is at the Marriott Marquis, 1535 Broadway. Investors can register or schedule meetings via the conference website at https://spartancapital.com/spartan-capital-investor-conference-2025/.
LIXTE Biotechnology Holdings (Nasdaq: LIXT) on Oct 16, 2025 outlined Q4 priorities centered on advancing its lead candidate LB-100 and pursuing oncology-focused business development. The company said it is continuing clinical and preclinical work on LB-100 across prioritized tumor settings and maintaining collaborations with research centers.
LIXTE confirmed it is in advanced negotiations for potential acquisitions of complementary oncology assets to build a multi-asset platform, while noting no assurance any transaction will close. Operational readiness initiatives in quality, CMC, and regulatory alignment were highlighted to support study conduct and potential integration.
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