Welcome to our dedicated page for Lilly Eli & Co news (Ticker: LLY), a resource for investors and traders seeking the latest updates and insights on Lilly Eli & Co stock.
Eli Lilly and Company (NYSE: LLY) generates frequent news across cardiometabolic health, oncology, immunology, obesity and manufacturing expansion. This page aggregates recent press releases and third-party coverage so readers can follow how Lilly’s medicines, clinical programs and corporate actions are evolving over time.
Recent updates show Lilly reporting Phase 3 results for multiple late-stage assets. In obesity and cardiometabolic health, the company has shared topline data from ATTAIN-MAINTAIN, a Phase 3 trial of orforglipron, an investigational once-daily oral GLP-1 receptor agonist, for weight maintenance after prior treatment with injectable incretin therapies. Lilly has also reported results from TRIUMPH-4, a Phase 3 trial of retatrutide, an investigational triple agonist targeting GIP, GLP-1 and glucagon receptors, in adults with obesity or overweight and knee osteoarthritis, with co-primary endpoints in weight loss and pain reduction.
In immunology, Lilly has announced positive topline results from the TOGETHER-PsA Phase 3b trial, which evaluated concomitant use of Taltz (ixekizumab) and Zepbound (tirzepatide) versus Taltz alone in adults with active psoriatic arthritis and obesity or overweight with at least one weight-related condition. The company reports that the combination met the primary endpoint and all key secondary endpoints, supporting an integrated approach to treating psoriatic arthritis and obesity.
Oncology news includes updated EMBER-3 data for Inluriyo (imlunestrant) as monotherapy and in combination with Verzenio (abemaciclib) in ER-positive, HER2-negative advanced breast cancer, and Phase 3 BRUIN CLL-313 results showing that Jaypirca (pirtobrutinib) significantly reduced the risk of progression or death versus chemoimmunotherapy in treatment-naïve CLL/SLL without 17p deletions.
Corporate and strategic news items cover Lilly’s planned acquisition of Ventyx Biosciences, completion of the Adverum Biotechnologies tender offer, a strategic collaboration with Aktis Oncology, and a major manufacturing investment in a new active pharmaceutical ingredient facility in Huntsville, Alabama. Investors and observers can use this news feed to monitor clinical milestones, regulatory submissions, acquisitions, collaborations, financing activities and manufacturing expansions related to LLY.
Eli Lilly and Company (NYSE: LLY) will announce its first-quarter 2021 financial results on April 27, 2021. A conference call is scheduled for 9 a.m. Eastern time on the same day to discuss financial performance with investors and the media. Interested parties can access a live webcast through Lilly's investor website, with a replay available afterward. Lilly remains committed to its mission of improving lives through high-quality medicines and community involvement.
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Eli Lilly, Vir Biotechnology, and GlaxoSmithKline announced promising topline results from the Phase 2 BLAZE-4 trial, showing that the combination of bamlanivimab and VIR-7831 significantly reduced high viral loads in low-risk COVID-19 patients by 70% at day 7 compared to placebo. No related hospitalizations or deaths occurred by day 29. Preclinical data suggest the combination can combat resistant SARS-CoV-2 variants. An Emergency Use Authorization application for VIR-7831 has been submitted to the FDA, aiming to expedite its availability for COVID-19 treatment.
Eli Lilly announced positive patient-reported outcomes for Verzenio (abemaciclib) combined with standard endocrine therapy for high-risk early breast cancer. In the analysis presented at the 17th St. Gallen Conference, about 70-75% of patients reported minimal side effects. The previous monarchE trial showed a significant 28.7% reduction in breast cancer recurrence with Verzenio. Most patients reported similar quality of life and side effects between treatment arms, except increased diarrhea in those receiving Verzenio. The ongoing trial will continue to assess safety and other outcomes.
Eli Lilly and Company (LLY) announced that mirikizumab achieved primary and all key secondary endpoints in the Phase 3 LUCENT-1 trial for moderate to severe ulcerative colitis, demonstrating significant clinical remission and symptom improvement by Week 12. The study reported statistically significant results (p<0.0001) and rapid symptom relief within four weeks. Patient safety profile remained consistent with prior studies. Ongoing maintenance study LUCENT-2 aims to further evaluate mirikizumab's long-term effects. Full results will be disclosed in future publications.
Eli Lilly (NYSE: LLY) presented Phase 2 TRAILBLAZER-ALZ results, confirming that donanemab significantly slows cognitive decline in early Alzheimer's patients. The study demonstrated a 32% decline in the Integrated Alzheimer's Disease Rating Scale compared to placebo at 76 weeks, with notable amyloid plaque clearance. Secondary endpoints showed a 20-40% decline across various cognitive measures. Despite a 26.7% incidence of amyloid-related imaging abnormalities, ongoing discussions with regulators are promising, enhancing donanemab's potential for disease modification.
Eli Lilly and Company (NYSE: LLY) announced participation in the 2021 AACR Annual Meeting with presentations from its oncology portfolio. Highlights include data on Retevmo® (selpercatinib) for RET fusion-positive cancers beyond lung and thyroid cancers. The company will also showcase preclinical data for a selective estrogen receptor degrader, a BCL2 inhibitor, and next-generation KRAS-G12C and RET inhibitors. Retevmo received FDA’s Accelerated Approval last May, and further studies are aimed at expanding its application in various cancer types.
Eli Lilly reports promising results from the BLAZE-1 Phase 3 study, showing that bamlanivimab and etesevimab significantly lower COVID-19 hospitalizations and deaths in high-risk patients. Among 769 participants, the combination treatment led to an 87% reduction in events compared to placebo. No deaths occurred in the treatment group, while 15 occurred in the placebo group. The FDA and EMA support the emergency use of these treatments, emphasizing their potential as a life-saving option against COVID-19, especially with emerging variants.
Eli Lilly (NYSE: LLY) will present new data from ten studies at the virtual AD/PD 2021 conference from March 9-14, 2021. The TRAILBLAZER-ALZ phase 2 study demonstrated that donanemab significantly slowed cognitive decline in early symptomatic Alzheimer's patients compared to placebo. The conference will highlight Lilly's commitment to developing disease-modifying therapies and diagnostics for Alzheimer's disease, which currently affects over 50 million globally. The company aims to enhance early diagnosis and treatment options for this complex illness.