Welcome to our dedicated page for Lilly Eli & Co news (Ticker: LLY), a resource for investors and traders seeking the latest updates and insights on Lilly Eli & Co stock.
Eli Lilly and Company (NYSE: LLY) generates frequent news across cardiometabolic health, oncology, immunology, obesity and manufacturing expansion. This page aggregates recent press releases and third-party coverage so readers can follow how Lilly’s medicines, clinical programs and corporate actions are evolving over time.
Recent updates show Lilly reporting Phase 3 results for multiple late-stage assets. In obesity and cardiometabolic health, the company has shared topline data from ATTAIN-MAINTAIN, a Phase 3 trial of orforglipron, an investigational once-daily oral GLP-1 receptor agonist, for weight maintenance after prior treatment with injectable incretin therapies. Lilly has also reported results from TRIUMPH-4, a Phase 3 trial of retatrutide, an investigational triple agonist targeting GIP, GLP-1 and glucagon receptors, in adults with obesity or overweight and knee osteoarthritis, with co-primary endpoints in weight loss and pain reduction.
In immunology, Lilly has announced positive topline results from the TOGETHER-PsA Phase 3b trial, which evaluated concomitant use of Taltz (ixekizumab) and Zepbound (tirzepatide) versus Taltz alone in adults with active psoriatic arthritis and obesity or overweight with at least one weight-related condition. The company reports that the combination met the primary endpoint and all key secondary endpoints, supporting an integrated approach to treating psoriatic arthritis and obesity.
Oncology news includes updated EMBER-3 data for Inluriyo (imlunestrant) as monotherapy and in combination with Verzenio (abemaciclib) in ER-positive, HER2-negative advanced breast cancer, and Phase 3 BRUIN CLL-313 results showing that Jaypirca (pirtobrutinib) significantly reduced the risk of progression or death versus chemoimmunotherapy in treatment-naïve CLL/SLL without 17p deletions.
Corporate and strategic news items cover Lilly’s planned acquisition of Ventyx Biosciences, completion of the Adverum Biotechnologies tender offer, a strategic collaboration with Aktis Oncology, and a major manufacturing investment in a new active pharmaceutical ingredient facility in Huntsville, Alabama. Investors and observers can use this news feed to monitor clinical milestones, regulatory submissions, acquisitions, collaborations, financing activities and manufacturing expansions related to LLY.
Eli Lilly announced a positive scientific opinion from the European Medicines Agency's Committee for Medicinal Products for Human Use for bamlanivimab alone and in combination with etesevimab. These therapies are recommended for treating COVID-19 in patients aged 12 and older at high risk of severe disease, who do not require supplemental oxygen. Data from the BLAZE-1 trial indicated a 70% reduction in hospitalizations. Lilly aims to provide affordable access globally, especially in low- and middle-income countries, while emphasizing that these treatments are not FDA-approved and carry potential risks.
Loxo Oncology at Lilly announced the publication of data from the pirtobrutinib (LOXO-305) global Phase 1/2 BRUIN clinical trial in relapsed chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (SLL), and other non-Hodgkin lymphomas. Published in The Lancet, findings from the trial demonstrate safety and efficacy across 323 patients. The company plans to initiate four global Phase 3 studies in 2021 to further advance pirtobrutinib’s development, addressing unmet therapeutic needs in patients previously treated with standard care options.
Tirzepatide, from Eli Lilly (NYSE: LLY), demonstrated superior reductions in A1C and body weight compared to semaglutide in the 40-week SURPASS-2 trial involving 1,879 adults with type 2 diabetes. The 15 mg dose of tirzepatide achieved a 2.46% reduction in A1C and a weight loss of 12.4 kg. Notably, 51% of participants on 15 mg reached an A1C below 5.7%, outpacing semaglutide's 20%. Safety profiles were similar, primarily showing gastrointestinal-related adverse events. These results indicate the potential of tirzepatide as a leading treatment option for managing type 2 diabetes.
Eli Lilly and Company and Incyte announced positive top-line results from the BRAVE-AA2 Phase 3 trial for baricitinib in treating severe alopecia areata (AA). Both 2-mg and 4-mg doses showed statistically significant scalp hair regrowth at Week 36 compared to placebo. Baricitinib, designated as Breakthrough Therapy by the FDA, aims to address the unmet needs of AA patients, with no current FDA-approved treatments available. The trial involved 546 diverse participants, with no reported severe adverse events. Detailed results will be presented at upcoming conferences.
The U.S. government has purchased a minimum of 100,000 doses of bamlanivimab (LY-CoV555) and etesevimab (LY-CoV016) from Eli Lilly for $210 million to treat mild to moderate COVID-19 in high-risk patients. This follows their emergency use authorization for such treatments. Additional doses may be purchased, totaling up to 1,200,000 units under certain conditions. The NIH recommends these antibodies to help reduce severe COVID-19 cases. The purchase is part of Lilly's ongoing efforts to combat COVID-19 with their neutralizing antibodies.
Welldoc and Eli Lilly have announced a collaboration to integrate Welldoc's BlueStar software into Lilly's connected insulin solutions. This partnership aims to develop an updated version of the BlueStar app, which will include insulin dosing data from multiple Lilly insulins. The app, FDA-cleared for diabetes management, supports insulin titration and integrates monitoring tools. Lilly plans to submit regulatory approvals in 2021 and commercialize the platform in the U.S. This collaboration seeks to enhance diabetes care through innovative technology.
Eli Lilly and Company (NYSE: LLY) will participate in the Cowen and Company 41st Annual Health Care Conference on March 4, 2021, at 9:10 a.m. Eastern Time. Chief Scientific Officer Daniel Skovronsky will engage in a fireside chat during the event. Investors and media can access a live audio webcast through Lilly's Investor website, with a replay available for approximately 90 days post-event. Lilly continues its commitment to healthcare innovation, focusing on developing life-changing medicines for global communities.
Eli Lilly and Rigel Pharmaceuticals have announced a global exclusive license agreement to co-develop Rigel's RIPK1 inhibitor, R552, targeting autoimmune and inflammatory diseases. Lilly will make an upfront payment of $125 million and could pay up to $835 million in milestone payments, plus royalties. R552 has completed Phase 1 trials and will enter Phase 2 trials in 2021. Lilly will lead clinical development and commercialization efforts, while Rigel retains co-commercialization rights in the U.S. This partnership seeks to advance treatments in both immune and CNS disease areas.
Eli Lilly and Company's tirzepatide demonstrated significant reductions in A1C levels and body weight in phase 3 clinical trials SURPASS-3 and SURPASS-5 for adult patients with type 2 diabetes. After 52 weeks and 40 weeks, respectively, significant endpoints were achieved, with the highest dose (15 mg) lowering A1C by up to 2.59% and body weight by 12.9 kg. Up to 62.4% of participants achieved A1C levels below 5.7%. The safety profile was comparable to existing GLP-1 receptor agonists, with gastrointestinal issues being the most frequent side effects. Results will be presented at upcoming scientific sessions.
On February 16, 2021, Eli Lilly and Company (NYSE: LLY) appointed Kimberly H. Johnson to its board of directors. Johnson, currently the executive vice president and COO of Fannie Mae, will contribute her expertise in technology, governance, and global risk management. She holds degrees in Economics from Princeton University and an MBA from Columbia Business School. Her addition is expected to enhance the board's capabilities, particularly in financial strategy and oversight.