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Liquidia Corporation Reports First Quarter 2026 Financial Results

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Liquidia (NASDAQ:LQDA) reported strong first quarter 2026 results driven by YUTREPIA inhalation powder. Product sales, net, reached $129.9 million, supporting net income of $52.9 million and adjusted EBITDA of $71.2 million. Cash and cash equivalents rose to $222.8 million.

Since YUTREPIA’s June 2025 launch, more than 4,500 unique prescriptions were received and about 3,750 patients started treatment, with conversion at or above 85%. Liquidia is also screening PH-ILD patients in Phase 4 Tyvaso/Tyvaso DPI transition and pivotal Phase 3 Re-Spire (L606) studies.

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Positive

  • YUTREPIA net product sales of $129.9 million in Q1 2026
  • Third consecutive profitable quarter with $52.9 million net income
  • Adjusted EBITDA of $71.2 million in Q1 2026
  • Cash and cash equivalents increased to $222.8 million from $190.7 million
  • Approximately 3,750 patients started YUTREPIA therapy since June 2025 launch
  • Prescription-to-start conversion at or above 85% and over 980 prescribers

Negative

  • Research and development expenses increased to $12.6 million from $7.0 million
  • Selling, general and administrative expenses rose to $46.9 million from $30.1 million
  • Total other expenses, net, increased to $4.7 million from $2.9 million
  • Income tax expense of $3.9 million in Q1 2026 versus none in Q1 2025

News Market Reaction – LQDA

+25.60% 5.4x vol
91 alerts
+25.60% Session close to close
+27.2% Peak Tracked
-11.0% Trough Tracked
$5.06B Market Cap
5.4x Rel. Volume

In the May 11 session, LQDA gained 25.60%, reflecting a significant positive market reaction. Argus tracked a peak move of +27.2% during that session. Argus tracked a trough of -11.0% from its starting point during tracking. Our momentum scanner triggered 91 alerts that day, indicating high trading interest and price volatility. Trading volume was exceptionally heavy at 5.4x the daily average, suggesting very strong buying interest.

Data tracked by StockTitan Argus on the day of publication.

Market Context

The stock surged +25.6% in the session following this news. A strong positive reaction aligns with r...
Analysis

The stock surged +25.6% in the session following this news. A strong positive reaction aligns with recent earnings releases that often produced gains, as prior results moves averaged about 3.54%. The Q1 2026 report combines robust YUTREPIA sales, net income of $52.9M, and cash of $222.8M. Investors would also have weighed the effective S-3 shelf and recent insider sales when assessing how sustainable any upside might be.

Key Figures

YUTREPIA net sales: $129.9 million Net income: $52.9 million Adjusted EBITDA: $71.2 million +5 more
8 metrics
YUTREPIA net sales $129.9 million Product sales, net for Q1 2026
Net income $52.9 million Q1 2026 net income, third consecutive profitable quarter
Adjusted EBITDA $71.2 million Non-GAAP adjusted EBITDA for Q1 2026
Cash & equivalents $222.8 million Balance as of March 31, 2026
Service revenue $3.0 million Q1 2026, mainly Sandoz treprostinil promotion agreement
R&D expenses $12.6 million Q1 2026 research and development expenses
SG&A expenses $46.9 million Q1 2026 selling, general and administrative expenses
EPS (basic) $0.60 per share Q1 2026 basic earnings per share

Previous Earnings Reports

5 past events · Latest: Mar 05 (Positive)
Same Type Pattern 5 events
Date Event Sentiment 24h Move Catalyst
Mar 05 Q4/FY25 earnings Positive +0.4% Reported strong YUTREPIA sales, positive Q4 net income, and higher cash.
Nov 03 Q3 2025 earnings Positive +3.5% Showed early YUTREPIA launch momentum and swing toward profitability.
Aug 12 Q2 2025 earnings Positive +13.7% Highlighted successful YUTREPIA launch and promising ASCENT trial data.
May 08 Q1 2025 earnings Neutral -1.2% Provided financials while awaiting FDA action and outlined preparation for launch.
Mar 19 FY 2024 results Negative +1.2% Reported wider net loss and lower revenue while awaiting final YUTREPIA approval.

24h Move is the share-price change in the day after each event; other market factors may also have contributed.

Pattern Detected

Earnings and financial results have typically produced positive first-day moves, with 4 of 5 recent earnings-related releases seeing gains despite one negative fundamental update.

Recent Company History

Over the past year, Liquidia’s earnings news traced a shift from pre-approval losses to YUTREPIA-driven growth. In Q2 2025 and Q3 2025, launches and accelerating prescriptions supported improving profitability and higher cash balances. By Q4 2025 results on 2026-03-05, YUTREPIA product sales reached $148.3M for the year and $90.1M in Q4, with quarterly net income of $14.6M. Today’s Q1 2026 report extends that trajectory with higher net income and adjusted EBITDA.

Key Terms

adjusted ebitda, phase 4, phase 3, net product sales, +1 more
5 terms
adjusted ebitda financial
"net income of approximately $53 million, adjusted EBITDA of $71 million"
Adjusted EBITDA is a way companies measure how much money they make from their core operations, like running a business, by removing certain costs or income that aren’t part of regular business activities. It helps investors see how well a company is doing without distractions from unusual expenses or gains, making it easier to compare companies or track performance over time.
phase 4 medical
"Actively screening PH-ILD patients in Phase 4 Tyvaso and Tyvaso DPI transition"
Phase 4 is the stage after a drug or vaccine has been approved and is sold to the public, where regulators and companies keep watching how it performs in the real world to detect rare side effects, long‑term effects, or differences in effectiveness across different groups. Think of it as ongoing quality control for a product already on shelves; results can prompt label changes, safety warnings, sales impacts or recalls, all of which matter to investors evaluating risk and future revenue.
phase 3 medical
"pivotal Phase 3 Re-Spire study of L606"
Phase 3 is the late-stage clinical testing step for a new drug or medical treatment, where the product is given to large groups of patients to confirm effectiveness, monitor side effects, and compare it to standard care. Successful Phase 3 results are often the final scientific hurdle before regulators decide on approval and market launch—like passing a final exam before graduation—and can sharply change a company's valuation and future revenue prospects.
net product sales financial
"YUTREPIA inhalation powder net product sales of approximately $130 million"
Revenue a company earns from selling its products after subtracting returns, discounts, rebates and other allowances; it shows the actual money kept from product sales rather than the raw invoices. Investors watch net product sales because they reveal true customer demand and how much sales translate into cash that can drive profit, much like a shopowner counting money left after refunds and coupons to judge how well items are selling.
revenue interest financing agreement financial
"higher borrowings under our revenue interest financing agreement with HealthCare Royalty"
A revenue interest financing agreement is a deal where a company receives cash now in exchange for giving an investor a fixed percentage of future revenue until a set amount or time is reached. Think of it like selling a small slice of every sale to an investor instead of taking a traditional loan or issuing stock. Investors care because it affects future cash flow and returns—payments rise and fall with sales and don’t dilute ownership like equity.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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  • YUTREPIA® (treprostinil) inhalation powder net product sales of approximately $130 million in the first quarter of 2026
  • More than 4,500 unique patient prescriptions and approximately 3,750 patients treated between launch in June 2025 and April 30, 2026
  • Recorded third consecutive quarter of profitability, with net income of approximately $53 million, adjusted EBITDA of $71 million and an increase in cash and cash equivalents by $32 million compared to the fourth quarter of 2025
  • Actively screening PH-ILD patients in Phase 4 Tyvaso® and Tyvaso DPI® transition study and pivotal Phase 3 Re-Spire study of L606

MORRISVILLE, N.C., May 11, 2026 (GLOBE NEWSWIRE) -- Liquidia Corporation (NASDAQ: LQDA), a biopharmaceutical company driven by science and compassion to revolutionize care for patients with challenging respiratory and vascular diseases, today reported financial results for the first quarter ended March 31, 2026. The company will also host a webcast at 8:30 a.m. ET on May 11, 2026, to discuss its financial results and provide a corporate update.

Dr. Roger Jeffs, Liquidia’s Chief Executive Officer, said: “In its third full quarter on the market, YUTREPIA continued to demonstrate sustained uptake in pulmonary arterial hypertension (PAH) and pulmonary hypertension associated with interstitial lung disease (PH-ILD), consistent with its growing adoption as the preferred inhaled prostacyclin of choice. Having initiated additional Phase 4 studies of YUTREPIA and our pivotal Phase 3 Re-Spire study of L606, our focus in 2026 is on making the full benefit of prostacyclin therapy available to more patients who need it, across a broader set of serious pulmonary and vascular diseases where high unmet need remains prevalent.”

YUTREPIA Commercial Launch Highlights (as of April 30, 2026)

  • Received more than 4,500 unique patient prescriptions since launch in June 2025
  • Started approximately 3,750 patients on treatment since launch in June 2025
  • Prescription-to-start conversion remained strong at or above the 85% level as previously reported
  • Increased total number of prescribers to more than 980 since launch
  • Increased the number of prescribers that have prescribed YUTREPIA to at least 5 patients by approximately 25% since end of February to approximately 270

First Quarter 2026 Financial Results

YUTREPIA sales led to the company’s third consecutive quarter of profitability with net income of $52.9 million and positive non-GAAP adjusted EBITDA of $71.2 million in the first quarter of 2026.

Cash and cash equivalents totaled $222.8 million as of March 31, 2026, compared to $190.7 million as of December 31, 2025.

Product sales, net, were $129.9 million for the three months ended March 31, 2026. We began shipping YUTREPIA to our customers in the United States in June 2025, following receipt of full FDA approval for YUTREPIA on May 23, 2025. We did not recognize any revenue from product sales during the three months ended March 31, 2025.

Service revenue, net, was $3.0 million for the three months ended March 31, 2026, compared to $3.1 million for the three months ended March 31, 2025. Service revenue, net was related primarily to the promotion agreement with Sandoz, Inc. pursuant to which we share profits from the sale of Treprostinil Injection in the United States. The decrease of $0.1 million was primarily due to the impact of unfavorable gross-to-net chargeback and managed care adjustments.

Cost of product sales was $11.1 million for the three months ended March 31, 2026. Cost of products sales is related to sales of YUTREPIA. We did not record any cost of product sales during the three months ended March 31, 2025.

Cost of service revenue was $0.8 million for the three months ended March 31, 2026, compared to $1.5 million for the three months ended March 31, 2025. The decrease from 2025 to 2026 reflects a lower allocation of the cost of our commercial field force to Treprostinil Injection resulting from the commercial launch of YUTREPIA in the second quarter of 2025.

Research and development expenses were $12.6 million for the three months ended March 31, 2026, compared to $7.0 million for the three months ended March 31, 2025. The increase of $5.6 million was due primarily due to a $2.5 million increase in clinical expenses for our L606 program, a $1.8 million increase in expenses related to our YUTREPIA research and development activities, and a $1.1 million increase in personnel expenses driven by higher headcount.

Selling, general and administrative expenses were $46.9 million for the three months ended March 31, 2026, compared to $30.1 million for the three months ended March 31, 2025. The increase of $16.8 million was primarily due to an $8.6 million increase in personnel expenses and a $1.7 million increase in stock-based compensation driven by higher headcount, a $7.9 million increase in commercial and consulting expenses to support the commercialization of YUTREPIA, and a $1.0 million increase in facilities and infrastructure expenses. These increases were partially offset by a $3.7 million decrease in legal fees related to our ongoing YUTREPIA-related litigation.

Total other expenses, net was $4.7 million for the three months ended March 31, 2026, compared to $2.9 million for the three months ended March 31, 2025. The increase of $1.8 million was primarily attributable to the higher borrowings under our revenue interest financing agreement with HealthCare Royalty Partners IV, L.P.

Income tax expense was $3.9 million for the three months ended March 31, 2026. We did not recognize any income tax expense during the three months ended March 31, 2025.

Net income for the three months ended March 31, 2026 was $52.9 million, or $0.60 per basic and $0.52 per diluted share, as compared to a net loss of $38.4 million, or $0.45 per basic and diluted share, for the three months ended March 31, 2025.
Webcast Information
Liquidia will host a live webcast at 8:30 a.m. Eastern Time on May 11, 2026, to discuss the first quarter 2026 financial results and corporate update. The webcast will be available on Liquidia's website at https://liquidia.com/investors/events-and-presentations. A rebroadcast of the event will be available and archived for a period of one year at the same location.

About YUTREPIA® (treprostinil) Inhalation Powder
YUTREPIA is an inhaled dry-powder formulation of treprostinil delivered through a convenient, low-effort, palm-sized device. YUTREPIA is indicated for the treatment of pulmonary arterial hypertension (PAH) and pulmonary hypertension associated with interstitial lung disease (PH-ILD) to improve exercise ability. YUTREPIA was designed using Liquidia’s PRINT® technology, which enables the development of drug particles that are precise and uniform in size, shape and composition, and that are engineered for enhanced deposition in the lung following oral inhalation. YUTREPIA was previously referred to as LIQ861 in investigational studies.

About L606 (liposomal treprostinil inhalation suspension)
L606 is an investigational, extended-release formulation of treprostinil administered twice-daily with a next-generation nebulizer. The L606 suspension uses a proprietary liposomal formulation to encapsulate treprostinil which can be released slowly at a controlled rate into the lung, enhancing drug exposure over an extended period of time. L606 is currently being evaluated in an open-label study in the United States for treatment of pulmonary arterial hypertension (PAH) and pulmonary hypertension associated with interstitial lung disease (PH-ILD) and is the subject of Re-Spire, a global pivotal placebo-controlled efficacy study for the treatment of PH-ILD.

About Treprostinil Injection
Treprostinil Injection is the first-to-file, fully substitutable generic treprostinil for parenteral administration. Treprostinil Injection contains the same active ingredient, same strengths, same dosage form and same inactive ingredients as Remodulin® (treprostinil) and is offered to patients and physicians with the same level of service and support, but at a lower price than the branded drug. Liquidia PAH promotes the appropriate use of Treprostinil Injection for the treatment of PAH in the United States in partnership with its commercial partner, Sandoz, who holds the Abbreviated New Drug Application (ANDA) with the FDA.

About Pulmonary Arterial Hypertension (PAH)
Pulmonary arterial hypertension (PAH) is a rare, chronic, progressive disease caused by hardening and narrowing of the pulmonary arteries that can lead to right heart failure and eventually death. Currently, an estimated 45,000 patients are diagnosed and treated in the United States. There is currently no cure for PAH, so the goals of existing treatments are to alleviate symptoms, maintain or improve functional class, delay disease progression and improve quality of life.

About Pulmonary Hypertension Associated with Interstitial Lung Disease (PH-ILD)
Pulmonary hypertension (PH) associated with interstitial lung disease (ILD) includes a diverse collection of up to 150 different pulmonary diseases, including interstitial pulmonary fibrosis, chronic hypersensitivity pneumonitis, connective tissue disease-related ILD, and chronic pulmonary fibrosis with emphysema (CPFE) among others. Any level of PH in ILD patients is associated with poor 3-year survival. A current estimate of PH-ILD prevalence in the United States is greater than 60,000 patients, though actual prevalence in many of these underlying ILD diseases is not yet known due to factors including underdiagnosis and lack of approved treatments until March 2021 when inhaled treprostinil was first approved for this indication.

About Liquidia Corporation
Liquidia Corporation is a biopharmaceutical company driven by science and compassion to revolutionize care for patients with challenging respiratory and vascular diseases through precise, innovative therapies and applications of its proprietary PRINT® technology. PRINT enabled the development of YUTREPIA® (treprostinil) inhalation powder for the treatment of pulmonary arterial hypertension (PAH) and pulmonary hypertension associated with interstitial lung disease (PH-ILD).  The company is also developing L606, an investigational extended-release formulation of treprostinil administered twice-daily with a next-generation nebulizer, and currently markets generic Treprostinil Injection for the treatment of PAH. To learn more about Liquidia, please visit www.liquidia.com.

Tyvaso®, Tyvaso DPI® and Remodulin® are registered marks of United Therapeutics Corporation.

Cautionary Statements Regarding Forward-Looking Statements
This press release may include forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. All statements contained in this press release other than statements of historical facts, including statements regarding our future results of operations and financial position, our strategic and financial initiatives, our business strategy and plans and our objectives for future operations, are forward-looking statements.

Forward-looking statements, including statements regarding clinical trials, clinical studies and other clinical work (including the funding therefor, anticipated patient enrollment, safety data, study data, trial outcomes, timing or associated costs), regulatory applications and related submission contents and timelines, the timelines or outcomes related to patent litigation with United Therapeutics in the U.S. District Court for the District of Delaware and U.S. District Court for the Middle District of North Carolina, or other litigation between Liquidia and United Therapeutics or others, including rehearings or appeals of decisions in any such proceedings, the issuance of patents by the USPTO and our ability to execute on our strategic or financial initiatives, our estimates regarding future expenses, capital requirements and needs for additional financing, and potential revenue and profitability of YUTREPIA involve significant risks and uncertainties and actual results could differ materially from those expressed or implied herein. Our ability to maintain YUTREPIA’s approval and to continue commercialization of YUTREPIA remain subject to ongoing litigation in which United Therapeutics is seeking injunctive relief, which could block our ability to continue to sell YUTREPIA for one or both of PAH and PH-ILD. The words “anticipate,” “believe,” “continue,” “could,” “estimate,” “expect,” “intend,” “may,” “plan,” “potential,” “predict,” “project,” “should,” “target,” “would,” and similar expressions are intended to identify forward-looking statements. We have based these forward-looking statements largely on our current expectations and projections about future events and financial trends that we believe may affect our financial condition, results of operations, business strategy, short-term and long-term business operations and objectives and financial needs. These forward-looking statements are subject to a number of risks discussed in our filings with the SEC, as well as a number of uncertainties and assumptions. Moreover, we operate in a very competitive and rapidly changing environment and our industry has inherent risks. New risks emerge from time to time. It is not possible for our management to predict all risks, nor can we assess the impact of all factors on our business or the extent to which any factor, or combination of factors, may cause actual results to differ materially from those contained in any forward-looking statements we may make. In light of these risks, uncertainties and assumptions, the future events discussed in this press release may not occur and actual results could differ materially and adversely from those anticipated or implied in the forward-looking statements. Nothing in this press release should be regarded as a representation by any person that these goals will be achieved, and we undertake no duty to update our goals or to update or alter any forward-looking statements, whether as a result of new information, future events or otherwise.

Use of Non-GAAP Financial Information
This press release and the accompanying tables include U.S. Generally Accepted Accounting Principals (GAAP) and non-GAAP financial measures. For a description of such non-GAAP financial measures, including the reasons for using such measures, and reconciliations of such non-GAAP financial measures to the most directly comparable financial measures prepared in accordance with GAAP, please see the section entitled “About Non-GAAP Financial Information” below.

Contact Information
Investors:
Jason Adair
Chief Business Officer
919.328.4350
Jason.adair@liquidia.com

Media:
media@liquidia.com

Liquidia Corporation
Select Consolidated Balance Sheet Data
(in thousands)

  March 31,  December 31, 
  2026  2025 
Cash and cash equivalents $222,786  $190,680 
Total assets $401,533  $327,934 
Total liabilities $292,954  $283,186 
Accumulated deficit $(573,451) $(626,313)
Total stockholders’ equity $108,579  $44,748 
       

Liquidia Corporation
Consolidated Statements of Operations and Comprehensive Income (Loss)
(unaudited)
(in thousands, except share and per share amounts)

  Three Months Ended
March 31,
  2026  2025 
Revenues:      
Product sales, net$129,881 $ 
Service revenue, net 2,984  3,120 
Total revenue 132,865  3,120 
Costs and expenses:      
Cost of product sales 11,079   
Cost of service revenue 773  1,517 
Research and development 12,571  6,966 
Selling, general and administrative 46,938  30,062 
Total costs and expenses 71,361  38,545 
Income (loss) from operations 61,504  (35,425)
Other income (expense):      
Interest income 1,772  1,728 
Interest expense (6,494) (4,670)
Total other expense, net (4,722) (2,942)
Income (loss) before income taxes 56,782  (38,367)
Income tax expense 3,920   
Net income (loss) and comprehensive income (loss)$52,862 $(38,367)
Net income (loss) per common share, basic$0.60 $(0.45)
Net income (loss) per common share, diluted$0.52 $(0.45)
Weighted average common shares outstanding, basic 88,006,244  85,172,696 
Weighted average common shares outstanding, diluted 101,112,095  85,172,696 
       

About Non-GAAP Financial Information
To supplement our financial results presented in accordance with U.S. Generally Accepted Accounting Principles (GAAP), this press release includes certain non-GAAP financial measures, such as Adjusted EBITDA. We believe the use of such non-GAAP financial measures provides investors with additional insight into our operational performance. While we compute non-GAAP financial measures using a consistent method from quarter to quarter and year to year, we may consider whether other significant items that arise in the future should be excluded from our non-GAAP financial measures.

Adjusted EBITDA is a non-GAAP measure that represents net income for the period before the impact of interest income, interest expense, other income and expense, income taxes, depreciation and amortization, and certain items that impact comparison of the performance of our business either period-over-period or with other businesses.

Adjusted EBITDA should not be considered in isolation or as a substitute to net income or any other measure of financial performance calculated and presented in accordance with GAAP. Our calculation of Adjusted EBITDA may not be comparable to similarly titled measures of other companies because other companies may not calculate them in the same manner as we calculate these measures.

For a reconciliation of such non-GAAP financial measures to the most directly comparable financial measures prepared in accordance with GAAP, please see the table titled “Reconciliation of Non-GAAP Financial Information” below.

Liquidia Corporation
Reconciliation of Non-GAAP Financial Information
Reconciliation of Net Income (Loss) to Adjusted EBITDA
(unaudited)
(in thousands)

  Three Months Ended Three Months Ended
  March 31, December 31,
  2026
 2025
Net income $52,862 $14,555
Interest expense, net  4,722  5,232
Income tax expense  3,920  -
Depreciation and amortization  497  321
EBITDA $62,001 $20,108
Stock-based compensation  9,217  7,206
Adjusted EBITDA $71,218 $27,314



FAQ

What were Liquidia (NASDAQ:LQDA) Q1 2026 revenues and earnings?

Liquidia reported Q1 2026 net product sales of $129.9 million and net income of $52.9 million. According to Liquidia, adjusted EBITDA reached $71.2 million, marking the company’s third consecutive profitable quarter as YUTREPIA inhalation powder continued to scale commercially.

How is YUTREPIA performing commercially for Liquidia (LQDA) through April 30, 2026?

YUTREPIA has generated approximately $130 million in Q1 2026 net product sales. According to Liquidia, since its June 2025 launch it has received over 4,500 unique prescriptions, started about 3,750 patients, maintained conversion at or above 85%, and surpassed 980 prescribers.

What changes did Liquidia (LQDA) report in operating expenses for Q1 2026?

Liquidia reported higher research and development and selling, general and administrative expenses in Q1 2026. According to Liquidia, R&D rose to $12.6 million and SG&A to $46.9 million, mainly from L606 clinical costs, YUTREPIA R&D, increased headcount, and commercialization spending.

How did Liquidia’s cash position change in the first quarter of 2026?

Liquidia ended March 31, 2026 with cash and cash equivalents of $222.8 million. According to Liquidia, this compares with $190.7 million at December 31, 2025, reflecting a cash increase of about $32 million driven primarily by YUTREPIA net product sales and profitability.

What clinical programs did Liquidia (LQDA) highlight alongside Q1 2026 results?

Liquidia highlighted ongoing work in pulmonary hypertension, including Phase 4 studies and the Phase 3 Re-Spire trial of L606. According to Liquidia, it is actively screening PH-ILD patients in a Tyvaso/Tyvaso DPI transition study and in the pivotal Phase 3 Re-Spire study.

How did Liquidia’s service revenue from the Sandoz Treprostinil Injection agreement change in Q1 2026?

Service revenue, primarily from the Sandoz Treprostinil Injection promotion agreement, was $3.0 million in Q1 2026. According to Liquidia, this compares with $3.1 million in Q1 2025, with the $0.1 million decrease driven by unfavorable gross-to-net chargeback and managed care adjustments.