MAIA Biotechnology, Inc. develops targeted immunotherapies for cancer, with news centered on its lead investigational therapy, ateganosine, also known as THIO, for non-small cell lung cancer. Company updates frequently address the THIO-101 clinical program, ateganosine’s telomere-targeting and immune-activating mechanism, use with the checkpoint inhibitor cemiplimab, and FDA Fast Track designation in third-line NSCLC.
Recurring MAIA news also includes oncology data presentations, shareholder letters on the development pipeline, clinical-site and trial-expansion updates, and financing activity tied to its clinical programs. Capital-market announcements have included common stock offerings, shelf registration use, and stated uses of proceeds for clinical trials, working capital, and general corporate purposes.
MAIA Biotechnology announced promising results for its lead drug candidate, THIO, from a pre-clinical study on hepatocellular carcinoma (HCC) presented at the SITC 37th Annual Meeting. The study showed that THIO enhances the efficacy of immune checkpoint inhibitors by directly killing cancer cells and stimulating an anti-tumor immune response. Notably, THIO, which received Orphan Drug Designation from the FDA, exhibited complete responses in several HCC models with no dose-limiting toxicities. MAIA emphasizes THIO's potential to address the growing need for effective HCC treatments.
MAIA Biotechnology, Inc. reported financial results for Q3 2022, highlighting a net loss of approximately $3.9 million, an improvement from $5.2 million in Q3 2021. The company’s cash position increased to about $14.1 million, sufficient for 12 months of operations. Key developments include an oral presentation on the THIO platform and ongoing THIO-101 trial disclosures. MAIA was added to the Longevity Stock Index, emphasizing its focus on cancer immunotherapies targeting telomeres.
MAIA Biotechnology, Inc. (NYSE American: MAIA) announced its participation in the ThinkEquity Conference on October 26 at 3:00 pm ET. The management team will present and host investor meetings during the event. A webcast of the presentation will be accessible via the Company's website, with a replay available for 30 days post-event. MAIA focuses on developing first-in-class oncology drugs, particularly THIO for NSCLC.
MAIA Biotechnology, Inc. (NYSE American: MAIA) announced it will present study results of the anticancer agent 6-thio-dG (THIO) for hepatocellular carcinoma (HCC) at the EORTC-NCI-AACR Symposium, occurring in Barcelona, Spain from Oct. 26-28, 2022. The data indicates THIO's high anticancer activity and improved tumor response when used sequentially with cemiplimab in HCC models. The U.S. FDA granted THIO Orphan Drug Designation for HCC earlier in 2022, a disease projected to exceed 1 million global cases by 2025.
Presentation is scheduled for Oct. 26 at 12:00pm CEST.
MAIA Biotechnology, Inc. (NYSE American: MAIA) will participate in the H.C. Wainwright 24th Annual Global Investment Conference from September 12-14. The management team is set to present on September 12 at 7:00 am ET and will hold investor meetings until September 14. A webcast of the presentation will be available on the Company's website, with a replay accessible for 30 days post-event. MAIA focuses on developing first-in-class oncology drugs aimed at improving cancer treatment outcomes.
MAIA Biotechnology, Inc. (NYSE American: MAIA) announced the upcoming presentation of its ongoing THIO-101 trial design at the ESMO Congress 2022 in Paris from September 9-13. The trial evaluates THIO, a telomere-targeting agent, in combination with cemiplimab for advanced non-small cell lung cancer (NSCLC). The first patient was enrolled in July 2022 in Australia. The presentation is scheduled for September 12, under the title: 'A Phase 2, Multicenter, Open-Label, Dose-Finding Study Evaluating THIO Sequenced with Cemiplimab in Patients with Advanced NSCLC'.
MAIA Biotechnology, Inc. has been selected to present its innovative THIO platform at the XIV International Round Table on Nucleosides in Stockholm, Sweden, from August 28 to 31, 2022. This platform showcases the modified nucleoside 6-thio-2’-deoxyguanosine (6-thio-dG) as a promising anticancer agent. The presentation will highlight how THIO may enhance immune responses and overcome therapy resistance. MAIA aims to develop THIO for non-small cell lung cancer patients resistant to existing checkpoint inhibitors.
MAIA Biotechnology, Inc. (NYSE American: MAIA) reported its second-quarter 2022 financial results, highlighting significant advancements in its clinical development of THIO, an immunotherapy for cancer. The company has initiated a Phase 2 trial for Non-Small Cell Lung Cancer (NSCLC) and received orphan drug designations from the FDA for two additional indications: Small Cell Lung Cancer (SCLC) and Hepatocellular Carcinoma (HCC). MAIA completed its IPO on August 1, raising $11.5 million, and reported a net loss of approximately $3.3 million for the quarter.
MAIA Biotechnology has received Orphan Drug Designation for THIO, its telomere-targeting agent, from the FDA. This designation applies to THIO's potential in treating small-cell lung cancer (SCLC) and builds on its previous designation for hepatocellular carcinoma (HCC). The company sees THIO as having a significant multi-billion-dollar opportunity in oncology. SCLC patients face a grim prognosis, with only 6% surviving five years post-diagnosis, highlighting the need for effective treatments.
MAIA Biotechnology, Inc. has successfully closed its initial public offering, issuing 2,000,000 shares at a price of $5.00 per share, resulting in gross proceeds of $10,000,000. The shares began trading on the NYSE American on July 28, 2022, under the ticker symbol MAIA. The proceeds will fund the Phase 2 trials of its product candidate THIO and support further development of telomere-targeting compounds. Underwriters are granted a 45-day option to purchase an additional 300,000 shares to cover overallotments.