Welcome to our dedicated page for Seres Therapeutics news (Ticker: MCRB), a resource for investors and traders seeking the latest updates and insights on Seres Therapeutics stock.
Seres Therapeutics, Inc. (Nasdaq: MCRB) is a clinical-stage live biotherapeutics company that regularly issues news about its microbiome-based drug programs, regulatory interactions, and corporate developments. The company focuses on oral live biotherapeutics for medically vulnerable patient populations, particularly adults undergoing allogeneic hematopoietic stem cell transplant (allo-HSCT) and other high-risk groups.
News about Seres often centers on its lead investigational candidate SER-155, including Phase 1b clinical data showing a significant reduction in bacterial bloodstream infections, systemic antibiotic exposure, and febrile neutropenia in allo-HSCT patients compared with placebo. Updates also cover regulatory designations for SER-155, such as Breakthrough Therapy and Fast Track status, and detailed feedback from the U.S. Food and Drug Administration on the design of a planned Phase 2 study.
Investors and followers of MCRB can expect announcements on clinical trial progress, investigator-sponsored studies in areas like immune checkpoint inhibitor–related enterocolitis, and research presentations at major medical meetings. Seres also issues press releases on mechanistic publications for its live biotherapeutics, including VOWST™, and on data generated from its MbTx® platform that support its broader live biotherapeutic strategy.
In addition to R&D updates, Seres publishes news on cost-reduction actions, cash runway expectations, leadership changes, and efforts to secure capital or partnerships to advance its pipeline. For those tracking MCRB, this news feed provides a centralized view of program milestones, scientific data, regulatory interactions, and corporate actions that shape the company’s live biotherapeutics portfolio.
Seres Therapeutics (MCRB) has achieved enrollment of 300 subjects in the ECOSPOR IV study for SER-109, an oral microbiome therapy targeting recurrent C. difficile infection (rCDI). This milestone is crucial for the upcoming Biologics License Application (BLA) submission planned for mid-2022. SER-109 has shown a 30.2% reduction in rCDI recurrence and is positioned to be the first FDA-approved microbiome therapy. The deal with Nestlé Health Science includes a $175 million upfront payment and potential further milestones, highlighting a significant financial backing for Seres.
Seres Therapeutics, Inc. (Nasdaq: MCRB) announced participation in three investor conferences. Management will engage in a pre-recorded fireside chat at the H.C. Wainwright 23rd Annual Global Investment Conference on September 13, 2021. Additionally, a fireside chat is scheduled for September 15, 2021, at the Morgan Stanley 19th Annual Global Healthcare Conference. Lastly, Seres will hold investor meetings during the Oppenheimer Fall Healthcare Life Sciences & Med Tech Summit on September 22, 2021. Webcast replays will be available on their website post-event.
Seres Therapeutics (Nasdaq: MCRB) announced that Eric Shaff, President and CEO, will discuss the company at the Canaccord Genuity 41st Annual Growth Conference on August 11 at 9:00 a.m. ET. A webcast replay will be available on the company's website two hours post-event and will be archived for 21 days.
Seres Therapeutics specializes in microbiome therapeutics with its SER-109 program being a first-ever positive pivotal clinical result for a targeted microbiome drug candidate. The company is also advancing SER-301 and SER-155 in clinical studies.
Seres Therapeutics (Nasdaq: MCRB) announced its second quarter 2021 financial results, reporting a net loss of $48.3 million, up from $20.7 million year-over-year, primarily due to increased clinical expenses. The company highlighted significant progress with SER-109, nearing target enrollment for its safety study, and plans to file a Biologics License Application to obtain FDA approval. A license agreement with Nestlé Health Science will bolster funding and commercialization efforts for SER-109. However, SER-287's Phase 2b trial for ulcerative colitis did not meet primary endpoints, leading to the closure of parts of the study.
Seres Therapeutics, Inc. (Nasdaq: MCRB) will host a conference call on August 3, 2021, at 8:30 a.m. ET to discuss its second quarter 2021 results and provide a general business update. Interested parties can join by dialing 844-277-9450 (domestic) or 336-525-7139 (international), using conference ID 6519859. The company is a leader in microbiome therapeutics, with its SER-109 program achieving positive pivotal clinical results and receiving Breakthrough Therapy and Orphan Drug designations from the FDA for treating recurrent C. difficile infection.
Seres Therapeutics, Inc. (Nasdaq: MCRB) held a conference call to discuss topline results from the Phase 2b ECO-RESET study evaluating SER-287 for mild-to-moderate ulcerative colitis. The company has also advanced SER-109 for recurrent C. difficile infection, achieving positive pivotal clinical results and receiving Breakthrough Therapy and Orphan Drug designations from the FDA. Current evaluations include SER-301 and SER-155 in ongoing Phase 1b studies. The press release includes forward-looking statements highlighting potential challenges in profitability and clinical development.
Seres Therapeutics (MCRB) announced topline results from its Phase 2b ECO-RESET study of SER-287 for mild-to-moderate ulcerative colitis. The study failed to meet its primary endpoint for improving clinical remission rates compared to placebo, with remission rates of 10.3% and 10.6% for full and step-down doses respectively, against 11.6% for placebo. Adverse events were reported in 67.6% of subjects in the active treatment arms. Following these results, the company will close the open label portions of the study and focus on advancing SER-109, SER-301, and their early-stage pipeline.
Seres Therapeutics, Inc. (Nasdaq: MCRB) has partnered with Nestlé Health Science to co-commercialize SER-109, a microbiome therapy targeting recurrent Clostridioides difficile infection, in the U.S. and Canada. Seres will receive $175 million upfront and $125 million upon FDA approval, plus up to $225 million in sales milestones. Upon commercialization, Seres will earn 50% of profits. SER-109 aims to be the first FDA-approved microbiome therapy, with promising clinical results indicating a 27% absolute reduction in CDI recurrence. A Joint Steering Committee will oversee collaboration activities.
Seres Therapeutics (Nasdaq: MCRB) will host a virtual investor event on June 21, 2021, from 8:30 a.m. to 10:00 a.m. ET, to discuss its investigational therapies SER-287 and SER-301 for ulcerative colitis (UC). Management and Dr. Stephen Hanauer will highlight the UC patient burden and the need for new treatments. SER-287 is in a Phase 2b trial for active mild-to-moderate UC, with data expected mid-2021. SER-301 is under evaluation in a Phase 1b study. Interested participants can join via the company's website or conference call.
Seres Therapeutics, Inc. (Nasdaq: MCRB), a microbiome therapeutics leader, announced that its Chief Commercial and Strategy Officer, Terri Young, Ph.D., will present at the JMP Securities Life Sciences Conference on June 17, 2021, at 1:00 p.m. ET. The presentation will be accessible via an audio webcast on Seres’ website and will be archived for 21 days post-event. Seres is developing a novel class of multifunctional bacterial therapies, with its SER-109 program targeting recurrent C. difficile infection and SER-287 aimed at pediatric ulcerative colitis.