Mediwound Stock Price, News & Analysis

MediWound (NASDAQ: MDWD) published a post hoc analysis in Wounds journal comparing their EscharEx® treatment to SANTYL® for venous leg ulcers (VLUs). The analysis, based on Phase II ChronEx trial data, demonstrated superior clinical performance of EscharEx over SANTYL, the only FDA-cleared enzymatic debridement agent currently available.

Key findings showed that 63% of EscharEx patients achieved complete debridement at 2 weeks versus 0% in the SANTYL group. The median time to debridement was 9 days for EscharEx, while SANTYL did not achieve this milestone. Wound Bed Preparation was achieved by 50% of EscharEx patients in 2 weeks compared to 0% with SANTYL. Notably, wound closure rates were 33% for EscharEx versus 25% for SANTYL, with significantly faster mean time to closure (48 days vs. 76 days). Both treatments showed similar safety profiles, though deep wound infection rates were lower in the EscharEx group (11% vs. 38%).

MediWound Ltd. (NASDAQ: MDWD), a leader in enzymatic therapeutics for tissue repair, has scheduled its first quarter 2025 financial results announcement for Wednesday, May 21, 2025. The company will host a conference call and webcast at 8:30 a.m. Eastern Time following the results release.

Investors can access the call through various channels including toll-free (1-844-676-8833), Israel (1-80-921-2373), and international (1-412-634-6869) numbers. A webcast replay will be available in the Investors section of MediWound's website after the call.

MediWound (Nasdaq: MDWD) announced plans to present 10 scientific abstracts at two major wound care conferences: the Wound Healing Society (WHS) and the Symposium on Advanced Wound Care (SAWC) Spring 2025 in Grapevine, Texas.

The presentations will showcase new data on EscharEx®, their investigational enzymatic therapy for chronic wounds. Key highlights include:

• New in vitro data demonstrating EscharEx's selective proteolytic activity
• Results showing superior debridement efficacy compared to SANTYL®
• Case studies on EscharEx's use in advanced diabetic foot ulcers (DFUs) and venous leg ulcers (VLUs)
• Updates on the ongoing VALUE Phase III study

The VALUE Phase III study is actively enrolling VLU patients across multiple sites, building on positive results from three completed Phase II studies that demonstrated EscharEx's efficacy and safety in wound care.

MediWound (NASDAQ: MDWD) reported its Q4 and full-year 2024 financial results, achieving $20.2 million in annual revenue, up from $18.7 million in 2023. The company projects $24 million revenue for 2025.

Key developments include initiating the VALUE Phase III trial for EscharEx® in venous leg ulcers, expanding strategic collaborations with industry leaders including Kerecis, and securing €16.5 million in European Innovation Council funding. NexoBrid® showed strong momentum with U.S. hospital orders increasing 42% in Q4.

Financial highlights: Q4 revenue reached $5.8 million with a 15.5% gross margin. Full-year net loss was $30.2 million ($3.03 per share), significantly higher than 2023's $6.7 million loss, primarily due to warrant revaluation expenses. The company ended 2024 with $43.6 million in cash and secured $25 million through a strategic PIPE investment led by Mölnlycke Health Care.

MediWound (Nasdaq: MDWD), a global leader in next-generation enzymatic therapeutics for tissue repair, has scheduled its Fourth Quarter and Full Year 2024 financial results release for Wednesday, March 19, 2025. The company will host a conference call and live webcast at 8:30 a.m. Eastern Time on the same day to discuss the financial results and provide corporate updates.

MediWound (Nasdaq: MDWD) announced the publication of its Phase III Children Innovative Debridement Study (CIDS) in Burns, the peer-reviewed Journal of the International Society for Burn Injuries. The study evaluated NexoBrid® compared to standard of care in pediatric patients with deep thermal burns.

The publication, titled "Open-Label RCT of the Efficacy and Safety of NexoBrid Compared to SOC in Children with Burns," presents findings that supported NexoBrid's label expansion for pediatric patients in the E.U. (2023) and U.S. (2024). The results confirm NexoBrid's superiority as a rapid, effective, and non-surgical alternative for eschar removal in pediatric burn patients.

Professor Jose Ramón Martínez-Méndez noted that pediatric burn patients account for approximately 30% of all burn cases and present unique challenges. NexoBrid provides a non-surgical solution that effectively removes eschar while preserving healthy tissue, addressing the need to protect viable dermis and improve outcomes.

MediWound (Nasdaq: MDWD), a specialist in enzymatic therapeutics for tissue repair, has announced its participation in the 45th Annual TD Cowen Health Care Conference in Boston. CEO Ofer Gonen will deliver a corporate overview on March 5, 2025, at 11:50 AM ET.

The presentation will be accessible through a live webcast, with registration available online. A replay will be made available on MediWound's website in the Events & Presentations section of the Investors area. The management team will also conduct one-on-one meetings with investors during the conference, which can be arranged through TD Cowen representatives.

MediWound (MDWD) has launched VALUE, a global Phase III pivotal trial for EscharEx® in treating venous leg ulcers (VLUs). The trial will evaluate the drug's efficacy and safety across 40 sites in the U.S. and Europe, enrolling 216 patients in a randomized, double-blind, placebo-controlled study.

The study will assess EscharEx's ability to achieve complete debridement and wound closure. Patients will receive up to eight daily applications over two weeks, followed by ten weeks of wound management. An interim analysis is expected in mid-2026 after 65% of patients complete treatment.

MediWound has established collaborations with Solventum, Mölnlycke, and MIMEDX to support the trial. The company also plans to initiate a head-to-head Phase II study comparing EscharEx to collagenase in 2025, and a Phase II/III trial for diabetic foot ulcers in 2026.

MediWound (Nasdaq: MDWD), a pioneer in enzymatic therapeutics for tissue repair, has announced its participation in the Oppenheimer 35th Annual Healthcare Life Sciences Conference. CEO Ofer Gonen will engage in a fireside chat on February 12, 2025, at 8:00 AM ET, moderated by Francois Brisebois, Managing Director and Senior Biotechnology Research Analyst at Oppenheimer.

The virtual event will be accessible through registration, and a webcast link will be available on MediWound's website under the Events & Presentations section. The management team will also conduct one-on-one meetings with investors during the conference, which can be arranged through Oppenheimer representatives.