Welcome to our dedicated page for Mesoblast news (Ticker: MESO), a resource for investors and traders seeking the latest updates and insights on Mesoblast stock.
Mesoblast Limited (NASDAQ: MESO; ASX: MSB) generates frequent news flow as it advances and commercializes allogeneic cellular medicines for severe inflammatory diseases. Company announcements highlight developments around its mesenchymal lineage cell therapy platform, led by Ryoncil (remestemcel-L-rknd) for pediatric steroid-refractory acute graft versus host disease (SR-aGvHD), as well as pipeline programs using remestemcel-L and rexlemestrocel-L.
News items commonly cover Ryoncil revenue trends, adoption across U.S. transplant centers, and reimbursement milestones such as assignment of a permanent HCPCS J-Code and expansion of coverage by commercial and government payers. Mesoblast also reports on trading updates, including quarterly activity reports that summarize revenue from cell therapy products and cash flow information released to the Australian Securities Exchange.
Investors following MESO news will see updates on clinical and regulatory progress, including pivotal trial plans for Ryoncil in adults with severe SR-aGvHD in collaboration with the NIH-funded Blood and Marrow Transplant Clinical Trials Network, and ongoing Phase 3 work with rexlemestrocel-L in chronic low back pain associated with degenerative disc disease. Company releases also discuss regulatory designations such as RMAT status for rexlemestrocel-L.
Corporate news includes financing arrangements like new credit facilities and convertible note programs, changes in board and executive roles, and participation in healthcare conferences. This news page aggregates Mesoblast’s press releases and related coverage so readers can review product performance, clinical milestones, capital structure updates, and governance developments in one place.
Mesoblast Limited (Nasdaq: MESO) has provided an update on its pain management product, rexlemestrocel-L, targeting chronic low back pain (CLBP) due to degenerative disc disease. The company expects to meet with the FDA this quarter to discuss the regulatory pathway following a Phase 3 trial showing durable pain reduction for at least two years. Mesoblast aims to include EU patients in its upcoming U.S. trial, potentially streamlining regulatory processes. A collaboration with Grünenthal could yield up to $112.5 million in milestone payments.
Mesoblast Limited (NASDAQ: MESO) reported operational and financial results for the period ending March 31, 2021. The company is advancing its regulatory discussions for remestemcel-L, targeting children with steroid-refractory aGVHD and adults with COVID-19 ARDS. Key highlights include significant mortality reduction in patients under 65 from COVID-19 ARDS using remestemcel-L with dexamethasone. However, the total revenue fell slightly to $1.9 million compared to $2.0 million the previous year. After a $110 million private placement, cash on hand stands at $158.3 million.
Mesoblast Limited (Nasdaq: MESO) announced it will host a webcast on June 2, 2021, to present operational highlights and financial results for the period ending March 31, 2021. The company specializes in allogeneic cellular medicines for inflammatory diseases, with a robust portfolio of late-stage product candidates and a global intellectual property portfolio extending through 2040. Mesoblast has completed Phase 3 trials for its products targeting advanced chronic heart failure and chronic low back pain, with ongoing developments for inflammatory conditions in children and adults.
Mesoblast Limited (Nasdaq:MESO) announced positive results from a Phase 2 trial published in Respiratory Research showing that its MSC product remestemcel-L significantly improved respiratory outcomes in COPD patients with high C-reactive protein (CRP) levels. Notable results included improvements in lung function metrics and a 55-meter increase in the six-minute walk test for patients receiving remestemcel-L compared to placebo. These findings suggest potential for remestemcel-L in treating severe lung inflammation, including COVID-19 related ARDS.
Mesoblast Limited (NASDAQ:MESO) announced operational and financial highlights for the quarter ending March 31, 2021. Key updates included a successful US$110 million private placement, boosting cash reserves to US$158.3 million. The trial results for remestemcel-L in COVID-19 patients showed a 46% reduction in mortality in those under 65, and 75% reduction when combined with dexamethasone. Positive outcomes were also reported for rexlemestrocel-L in chronic low back pain patients. Mesoblast is pursuing FDA discussions for potential approvals.
Mesoblast Limited (Nasdaq: MESO) announced significant results from a trial of remestemcel-L in COVID-19 patients with ARDS. The therapy reduced mortality by 46% in patients under 65 years old and by 75% when combined with dexamethasone. Additionally, patients experienced increased days off mechanical ventilation and shorter hospital stays. Mesoblast plans to discuss next steps with the FDA. The trial involved 222 patients, with dosing adapting to changing treatment protocols.
Mesoblast Limited (NASDAQ: MESO; ASX: MSB) announced a corporate update webcast scheduled for April 30, 2021, at 9:00 AM AEST. The company is a leader in allogeneic cellular medicines for inflammatory diseases, with significant advancements in product candidates for severe inflammation. They have completed Phase 3 trials of rexlemestrocel-L and have developed remestemcel-L for various inflammatory conditions. Mesoblast continues to expand its global intellectual property and has commercial partners in Japan and Europe.
Mesoblast Limited (Nasdaq: MESO) announced key operational highlights and upcoming milestones on March 30, 2021. The company successfully completed a US$110 million private placement, boosting its cash balance to US$187.5 million. Recent trial results for rexlemestrocel-L in chronic low back pain and chronic heart failure demonstrated significant pain reduction and decreased cardiac events. Mesoblast is engaged in a licensing agreement with Novartis focused on remestemcel-L for acute respiratory distress syndrome. Upcoming FDA meetings aim to discuss approval pathways for several treatments.
Mesoblast Limited (Nasdaq: MESO) announced the appointment of Philip J. Facchina to its Board of Directors. Facchina, with over 35 years of experience in corporate strategy and finance, is currently the Chief Strategy Officer at SurgCenter Development. His expertise in the ambulatory surgical center market and healthcare will support Mesoblast's strategic initiatives. The company recently completed a US$110 million private placement, with SurgCenter's principals as lead investors. Mesoblast focuses on allogeneic cellular medicines for inflammatory diseases and has advanced clinical programs targeting chronic conditions.
Mesoblast Limited (NASDAQ: MESO) successfully completed a US$110 million private placement, settling on March 8, 2021. The capital raised through the issuance of 60 million shares at A$2.30 each will support regulatory initiatives and operational activities concerning product candidates for steroid-refractory acute graft versus host disease, chronic heart failure, and chronic lower back pain. Post-placement, the pro-forma cash-on-hand is estimated at US$187.5 million.