Welcome to our dedicated page for Macrogenics news (Ticker: MGNX), a resource for investors and traders seeking the latest updates and insights on Macrogenics stock.
MacroGenics, Inc. (Nasdaq: MGNX) is a biopharmaceutical company that publicly describes its focus as discovering, developing, manufacturing and commercializing monoclonal antibody-based therapeutics for the treatment of cancer. The MGNX news page on Stock Titan aggregates company-issued updates and third-party coverage so readers can follow how MacroGenics communicates progress across its oncology pipeline, technology platforms and collaborations.
In its press releases, MacroGenics highlights clinical developments for programs such as lorigerlimab, a bispecific PD‑1 × CTLA‑4 DART® molecule, and a portfolio of antibody-drug conjugates including MGC026, MGC028 and MGC030. News items also describe partnered programs like MGD024 with Gilead Sciences, ZYNYZ® (retifanlimab-dlwr) with Incyte and TZIELD® (teplizumab-mzwv) associated with Sanofi, including milestone structures and royalty arrangements disclosed by the company.
MacroGenics regularly issues announcements on quarterly financial results, cash runway expectations, royalty purchase agreements and other financing-related transactions. Additional news covers participation in healthcare and investment conferences, leadership changes such as the appointment of a new President and Chief Executive Officer, and updates on strategic priorities for advancing its antibody-based oncology portfolio and technology platforms.
Investors and observers who follow MGNX news can use this page to review how MacroGenics reports progress in its clinical trials, describes its collaborations and outlines its financial position in official communications. Bookmarking the news feed provides a centralized view of press releases and related information that the company files or references in its SEC disclosures.
MacroGenics, Inc. (MGNX) announced its corporate progress and financial results for 2022, highlighting a cash runway extending through 2025 due to $250 million in non-dilutive funding. Preliminary data on lorigerlimab in metastatic castration-resistant prostate cancer (mCRPC) showed promising results, with 28.6% of patients achieving ≥ 50% PSA reduction. The TAMARACK study was modified to accelerate data readout. Total revenue increased to $151.9 million, up from $77.4 million in 2021, while net loss decreased to $119.8 million. Upcoming developments include a randomized Phase 2 study of lorigerlimab and advancements in ADC candidates.
MacroGenics has expanded its collaboration with Synaffix, adding up to four antibody-drug conjugate (ADC) programs. This agreement, evolving from a deal made in February 2022, includes potential payments of up to $2.2 billion and tiered royalties on net sales. MacroGenics can now pursue up to seven ADC programs, combining its proprietary technologies with Synaffix's advanced linker-payload technologies. This collaboration is positioned to enhance the development of innovative treatments for cancer, significantly leveraging Synaffix's GlycoConnect™, HydraSpace™, and toxSYN™ technologies for better efficacy and tolerability in ADCs.
MacroGenics, Inc. (Nasdaq: MGNX) has announced an agreement to sell its royalty interest on future global net sales of TZIELD to a subsidiary of DRI Healthcare Trust for up to $200 million. MacroGenics will receive a $100 million upfront payment for a single-digit royalty. The company retains other economic interests related to TZIELD, including potential milestone payments. Additionally, MacroGenics can earn an extra $50 million tied to specific advancements in TZIELD's treatment of type 1 diabetes and another $50 million based on net sales achievements.
MacroGenics, Inc. (Nasdaq: MGNX) announced it will release its fourth quarter 2022 financial results on March 15, 2023, after market close. A conference call to discuss these results and corporate progress will follow at 4:30 pm ET on the same day. Investors can register in advance for telephone participation, receiving a confirmation email with access details. A listen-only webcast will also be available on the company's website under the Investor Relations section. MacroGenics is focused on developing innovative monoclonal antibody therapeutics for cancer treatment, leveraging proprietary antibody technology and strategic collaborations.
MacroGenics, Inc. (Nasdaq: MGNX) announced its participation in significant investor conferences in March 2023. The company's President & CEO, Scott Koenig, will join the TD Cowen’s 43rd Annual Health Care Conference in Boston on March 7, 2023, for a corporate panel discussion. Additionally, he will participate in a fireside chat at the Barclays Global Healthcare Conference in Miami on March 14, 2023. Management will also engage in one-on-one meetings during both events. Webcasts of the presentations will be available on the company's Investor Relations website, with an archived replay for 30 days.
MacroGenics announced preliminary results from the Phase 1 trial of lorigerlimab for metastatic castration-resistant prostate cancer (mCRPC). In the cohort expansion, 12 of 42 patients achieved ≥ 50% reduction in PSA levels, while 9 patients (21.4%) had ≥ 90% reduction. The overall safety profile was manageable, with the company preparing to launch a Phase 2 study in mCRPC later in 2023. These findings are set to be presented at the ASCO-GU Symposium, showcasing the therapeutic potential of lorigerlimab and indicating promising efficacy in mCRPC patients.
ROCKVILLE, MD, Feb. 6, 2023 (GLOBE NEWSWIRE) -- MacroGenics, Inc. (Nasdaq: MGNX), a biopharmaceutical company focused on antibody-based therapeutics for cancer, has announced participation in two investor conferences. On February 9, 2023, President & CEO Scott Koenig, M.D., Ph.D., will engage in a fireside chat at the Guggenheim Healthcare Talks in New York. Following this, on February 14, 2023, he will present at the SVB Securities Global Biopharma Conference. Both events will also include one-on-one meetings. Interested parties can access a webcast of these presentations on the MacroGenics Investor Relations website, available for 30 days.
MacroGenics, a biopharmaceutical company focused on innovative antibody-based cancer therapies, will present at the 41st Annual J.P. Morgan Healthcare Conference. Scott Koenig, M.D., Ph.D., President & CEO, will deliver a business update on January 12, 2023, at 9:45 am PT / 12:45 pm ET. The presentation can be accessed via a webcast on MacroGenics' Investor Relations webpage, with an archived replay available for 30 days. MacroGenics leverages proprietary antibody technology platforms to develop its pipeline and establish strategic collaborations.
MacroGenics, Inc. (NASDAQ: MGNX) announced the appointment of Dr. Margaret A. Liu and Meenu Chhabra Karson to its Board of Directors, effective January 3, 2023. Dr. Liu, a renowned expert in gene therapy and immunotherapy, will join the Science and Technology Committee, while Ms. Karson will serve on the Audit Committee. The Board now consists of ten directors, nine of whom are independent, emphasizing strengthened leadership. Both appointees bring extensive experience from their previous roles in biopharmaceuticals, enhancing the company’s strategic capabilities in cancer therapeutics.
MacroGenics, Inc. (NASDAQ: MGNX) announced that the U.S. FDA has approved the Biologics License Application (BLA) for teplizumab, an anti-CD3 monoclonal antibody, previously developed by the company. Acquired by Provention Bio in 2018, teplizumab represents a significant advancement for individuals with type 1 diabetes. Provention will pay MacroGenics up to $395 million in milestone payments, including $60 million for the BLA approval. MacroGenics expects to maintain a cash runway into late 2024, based on current cash and anticipated partnership payments.