Mirum Pharmaceuticals Stock Price, News & Analysis

On March 10, 2021, Mirum Pharmaceuticals (Nasdaq: MIRM) granted stock options for 114,800 shares to five new employees under its 2020 Inducement Plan. Each option has an exercise price of $18.41, reflecting the closing price on the grant date. These options will vest over four years, with 25% vesting after one year. Mirum focuses on developing therapies for liver diseases, with its lead candidate, maralixibat, in late-stage development for conditions like Alagille syndrome and PFIC, with regulatory submissions pending.

Mirum Pharmaceuticals reported its fourth-quarter and year-end 2020 financial results, along with key business updates. The company aims to launch maralixibat for Alagille syndrome in 2021, pending FDA approval. Mirum secured approximately $400 million in capital to support operations over the next three years and has initiated several clinical studies for its pipeline products, including volixibat. Operating expenses surged to $37 million for Q4 2020, resulting in a net loss of $37.2 million. The company had cash and investments of $231.8 million by year-end.

Mirum Pharmaceuticals (Nasdaq: MIRM) announced its participation in several upcoming virtual investor conferences. Key dates include the SVB Leerink 10th Annual Global Healthcare Conference on February 26, 2021, and the Oppenheimer 31st Annual Healthcare Conference on March 17, 2021. Investors can access audio webcasts and presentations on Mirum’s Investor website. The company is focused on developing innovative treatments for liver diseases, with its lead candidate, maralixibat, in advanced stages for conditions like Alagille syndrome and PFIC.

Mirum Pharmaceuticals (Nasdaq: MIRM) announced the granting of non-qualified stock options to three new employees, totaling 21,500 shares. These options, priced at $21.22 each, are part of the 2020 Inducement Plan and will vest over four years. The decision aligns with Nasdaq Listing Rule 5635(c)(4). Mirum focuses on developing therapies for liver diseases, with its lead candidate, maralixibat, under NDA review for Alagille syndrome and a marketing application for PFIC accepted by the European Medicines Agency.

Mirum Pharmaceuticals announced the submission of its rolling New Drug Application (NDA) for maralixibat to the FDA, targeting cholestatic pruritus in patients with Alagille syndrome (ALGS) aged one year and older. ALGS is a rare liver disease without approved therapies. The NDA includes data from the ICONIC study, involving 86 patients and six-year follow-up. A U.S. launch is anticipated in late 2021, pending approval.

Mirum Pharmaceuticals has initiated patient enrollment in its Phase 2b VISTAS study for volixibat, targeting adult patients with primary sclerosing cholangitis (PSC). This chronic liver disease lacks approved therapies and is characterized by bile duct inflammation. The study will assess the efficacy of volixibat in reducing pruritus and include secondary endpoints like safety and quality of life measures over 28 weeks. Approximately 29,000 people in the U.S. suffer from PSC, underscoring the need for effective treatments.

Mirum Pharmaceuticals, Inc. (Nasdaq: MIRM) provided a corporate update ahead of the J.P. Morgan Healthcare Conference, highlighting significant 2021 developments. The company expects to complete its rolling NDA submission for maralixibat for Alagille syndrome by Q1 2021, while three clinical studies for maralixibat and volixibat are set to begin. With $231.8 million in cash and investments, including proceeds from recent financings, Mirum is financially equipped for growth and launch readiness. The company also appointed Alexey Kutahov, MD, to lead its European launch activities.

Mirum Pharmaceuticals (Nasdaq: MIRM) announced that its Board of Directors granted stock options to five new employees, totaling 49,900 shares, under the 2020 Inducement Plan. The options have an exercise price of $19.81, reflecting the closing stock price on January 8, 2021. Vesting occurs over four years, with 25% vesting after one year. Mirum is focused on developing therapies for liver diseases, and its lead candidate, maralixibat, is under NDA submission for Alagille syndrome treatment. The company’s application for pediatric PFIC2 treatment is under review by the European Medicines Agency.