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Merck & Co Stock Price, News & Analysis

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Welcome to our dedicated page for Merck & Co news (Ticker: MRK), a resource for investors and traders seeking the latest updates and insights on Merck & Co stock.

Merck & Co. (NYSE: MRK) is a global pharmaceutical leader with a 350-year legacy of medical innovation. This news hub provides investors and healthcare professionals with direct access to official announcements, financial disclosures, and research developments shaping the company's trajectory.

Track MRK's latest regulatory milestones, clinical trial results, and strategic partnerships through verified press releases and curated analysis. Our repository includes earnings call transcripts, FDA approval updates, and global health initiatives—all organized for efficient research and due diligence.

Key updates on therapeutic advancements in oncology, vaccines, and infectious diseases are maintained alongside financial performance data. Bookmark this page for real-time access to Merck's corporate communications and market-moving developments in the pharmaceutical sector.

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Merck Announces MK-1084, an Investigational KRAS G12C Inhibitor, Shows Antitumor Activity in Phase 1 Trial of Patients With Advanced Colorectal Cancer and Non-Small Cell Lung Cancer Whose Tumors Harbor KRAS G12C Mutations

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Merck announced promising Phase 1 KANDLELIT-001 trial results for MK-1084, their investigational KRAS G12C inhibitor, in treating advanced colorectal cancer (CRC) and non-small cell lung cancer (NSCLC) with KRAS G12C mutations. The drug showed encouraging antitumor activity both as monotherapy and in combinations. In CRC, MK-1084 demonstrated confirmed response rates of 38% as monotherapy, 46% when combined with cetuximab, and 38% with cetuximab plus chemotherapy. For NSCLC, response rates were 38% as monotherapy, notably 77% when combined with KEYTRUDA in untreated metastatic cases, and 53% with KEYTRUDA plus chemotherapy. The drug maintained a manageable safety profile across all treatment arms, with treatment-related adverse events ranging from 58% in monotherapy to 97% in combination therapies. Merck plans to advance MK-1084 to Phase 3 trials for both CRC and NSCLC treatments.
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Merck’s Investigational Zilovertamab Vedotin at 1.75 mg/kg Dose Plus Standard of Care Showed Promising Antitumor Activity, Including Complete Response Rate, in Patients With Relapsed/Refractory DLBCL in Phase 2 Portion of waveLINE-003 Trial

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Merck announced promising results from the Phase 2/3 waveLINE-003 study of zilovertamab vedotin combined with R-GemOx for treating relapsed/refractory DLBCL. At the 1.75 mg/kg dose, the combination achieved a 56.3% objective response rate, including 8 complete responses and 1 partial response in 16 patients. The study evaluated three dose levels (1.5, 1.75, and 2.0 mg/kg), with 1.75 mg/kg selected as the recommended Phase 2 dose based on efficacy and safety data. Treatment-related adverse events occurred in 98% of patients, with Grade ≥3 events in 63%. The drug is currently being evaluated in multiple Phase 2 and 3 trials, including waveLINE-010, waveLINE-007, and waveLINE-011, for various DLBCL treatment settings.
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Patritumab Deruxtecan Biologics License Application for Patients with Previously Treated Locally Advanced or Metastatic EGFR-Mutated Non-Small Cell Lung Cancer Voluntarily Withdrawn

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Daiichi Sankyo and Merck (MRK) have voluntarily withdrawn their Biologics License Application (BLA) for patritumab deruxtecan (HER3-DXd) in the treatment of EGFR-mutated non-small cell lung cancer (NSCLC). The withdrawal follows topline overall survival results from the HERTHENA-Lung02 phase 3 trial that failed to meet statistical significance. While the trial showed statistically significant progression-free survival (PFS), the overall survival data did not reach the required threshold. The decision is unrelated to a previous Complete Response Letter from June 2024 regarding third-party manufacturing facility inspection findings. The companies will present detailed trial results at the 2025 ASCO Annual Meeting. The safety profile remained consistent with previous trials, with no new safety signals identified.
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Merck Announces Third-Quarter 2025 Dividend

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Merck (NYSE: MRK) has announced its quarterly dividend payment for Q3 2025. The company's Board of Directors has declared a dividend of $0.81 per share of common stock. The dividend will be paid on July 8, 2025, to shareholders who are on record as of the close of business on June 16, 2025.

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IDeate-Esophageal01 Phase 3 Trial of Ifinatamab Deruxtecan Initiated in Certain Patients with Pretreated Advanced or Metastatic Esophageal Squamous Cell Carcinoma

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Merck (MRK) and Daiichi Sankyo have initiated the IDeate-Esophageal01 Phase 3 trial for ifinatamab deruxtecan (I-DXd), a potential first-in-class B7-H3 directed antibody drug conjugate. The trial will evaluate I-DXd versus standard chemotherapy in patients with advanced or metastatic esophageal squamous cell carcinoma (ESCC) who have progressed after platinum therapy and immunotherapy. ESCC represents 90% of global esophageal cancers with a dire 15-20% five-year survival rate. The trial's initiation follows promising results from the IDeate-PanTumor01 phase 1/2 trial presented at ESMO 2022 and 2023, which demonstrated encouraging responses in heavily pretreated ESCC patients.
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Merck to Present New Clinical and Outcomes Research Data at The American Thoracic Society’s (ATS) 2025 International Conference Demonstrating Commitment to Advancing Research in Pulmonary Arterial Hypertension

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<p><b>Merck (MRK)</b> announced it will present new clinical and outcomes research data on <b>pulmonary arterial hypertension (PAH)</b> at the ATS 2025 International Conference in San Francisco. The company will showcase nine presentations, including a significant pooled analysis of WINREVAIR™ (sotatercept-csrk) from the PULSAR, SPECTRA, and STELLAR studies, along with the ongoing SOTERIA open-label extension study.</p><p>Key presentations will feature long-term safety data, overall survival analysis, and research on PAH's impact across various patient populations. The data represents the largest analysis of WINREVAIR to date, evaluating its safety, tolerability, and efficacy when combined with background therapy for PAH treatment.</p>
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Merck Announces Phase 3 KEYNOTE-B96 Trial Met Primary Endpoint of Progression-Free Survival (PFS) in Patients With Platinum-Resistant Recurrent Ovarian Cancer Whose Tumors Expressed PD-L1 and in All Comers

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Merck (NYSE: MRK) announced positive results from its Phase 3 KEYNOTE-B96 trial evaluating KEYTRUDA (pembrolizumab) in combination with chemotherapy for platinum-resistant recurrent ovarian cancer. The trial met its primary endpoint of progression-free survival (PFS) in both PD-L1 expressing tumors and all comers. Significantly, the study achieved a secondary endpoint of overall survival (OS) in PD-L1 expressing tumors - marking the first time an immune checkpoint inhibitor-based regimen demonstrated an OS benefit in ovarian cancer. The KEYTRUDA-based treatment showed statistically significant improvements compared to placebo plus chemotherapy, with a safety profile consistent with previous studies. While KEYTRUDA is not yet approved for ovarian cancer treatment, these breakthrough results suggest potential new treatment options for this difficult-to-treat condition.
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FDA Approves Merck’s WELIREG® (belzutifan) for the Treatment of Adults and Pediatric Patients 12 Years and Older With Locally Advanced, Unresectable, or Metastatic Pheochromocytoma or Paraganglioma (PPGL)

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The FDA has approved Merck's (MRK) WELIREG® (belzutifan) for treating adults and pediatric patients 12 years and older with locally advanced, unresectable, or metastatic pheochromocytoma or paraganglioma (PPGL). This marks WELIREG's third indication in the U.S. and establishes it as the only approved and available treatment for eligible PPGL patients. PPGL is a rare condition affecting up to 2,000 people annually in the U.S. The approval is based on the LITESPARK-015 clinical trial, which enrolled 72 patients. The drug targets hypoxia-inducible factor-2 alpha (HIF-2α) and is administered orally at 120 mg once daily. Important safety considerations include risks during pregnancy, potential for severe anemia requiring blood transfusion, and possible severe hypoxia requiring discontinuation, supplemental oxygen, or hospitalization.

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Research on Novel Treatment Approaches and Scientific Advances From Merck’s Broad and Differentiated Oncology Portfolio and Pipeline to be Presented at ASCO 2025

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Merck (NYSE: MRK) will present extensive research from its oncology portfolio at the ASCO Annual Meeting (May 30-June 3, 2025), covering over 25 cancer types. Key highlights include first-time data for MK-1084, their KRAS G12C inhibitor, from the KANDLELIT-001 study in colorectal cancer and NSCLC. The company will showcase data on novel antibody-drug conjugates including zilovertamab vedotin and sacituzumab tirumotecan. Important updates include 5-year follow-up results for KEYTRUDA in renal cell carcinoma (KEYNOTE-564 trial) and WELIREG in VHL disease-associated tumors. Primary results from ASCENT-04/KEYNOTE-D19 trial evaluating KEYTRUDA plus sacituzumab govitecan-hziy in triple-negative breast cancer will be featured in ASCO's press program. Merck will host an Oncology Investor Event on June 2, 2025, to discuss their oncology strategy.
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Merck Animal Health and State of Kansas Announce $895 Million Investment in Manufacturing and Research & Development Facilities in De Soto

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Merck Animal Health (NYSE: MRK) has announced an $895 million expansion of its facilities in De Soto, Kansas, marking its largest economic development project in recent history. The investment includes $860 million for expanding the existing manufacturing facility and $35 million for research and development laboratories.

The 200,000-square-foot manufacturing expansion will enhance filling and freeze dryer capacity for large molecule vaccines and biologic products. Site preparation begins immediately, creating 2,500 construction jobs, with commercial manufacturing expected to start in 2030, generating over 200 full-time positions. Located in the Animal Health Corridor, this investment is part of Merck's broader commitment to invest more than $21 billion in domestic manufacturing and research capabilities between 2017 and 2028.

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FAQ

What is the current stock price of Merck & Co (MRK)?

The current stock price of Merck & Co (MRK) is $85.48 as of September 2, 2025.

What is the market cap of Merck & Co (MRK)?

The market cap of Merck & Co (MRK) is approximately 210.1B.
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Merck & Co

NYSE:MRK

MRK Rankings

#56 Ranked by Market Cap
#956 Ranked by Dividends

MRK Stock Data

210.11B
2.50B
0.07%
80.55%
1.04%
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