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Moderna Announces Late-Breaking Data to be Presented at ESMO Congress 2026

Moderna (MRNA) will present late-breaking and additional clinical data on intismeran autogene, its investigational mRNA-based individualized neoantigen therapy, at the ESMO Congress 2026 in Madrid from October 23-27.

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Moderna (MRNA) will present late-breaking and additional clinical data on intismeran autogene, its investigational mRNA-based individualized neoantigen therapy, at the ESMO Congress 2026 in Madrid from October 23-27.

The company’s Phase 3 melanoma study INTerpath-001 (intismeran plus pembrolizumab vs pembrolizumab alone) is scheduled in the Presidential Symposium on Saturday, October 24, at 4:30 PM CEST / 10:30 AM EDT. Two poster sessions will cover a Phase I study in resectable pancreatic ductal adenocarcinoma (Sunday, October 25, 12:00-12:45 PM CET) and the Phase 3 INTerpath-014 trial in high-risk stage I NSCLC (Monday, October 26, 12:00-12:45 PM CET). Intismeran autogene is jointly developed by Moderna and Merck (MSD outside the US and Canada).

Moderna will also host a live investor webcast on Saturday, October 24, at 7:00 PM CEST / 1:00 PM EDT, with a replay available for at least 30 days.

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Following this news, MRNA has gained 9.76%, reflecting a notable positive market reaction. Our momentum scanner has triggered 73 alerts so far, indicating high trading interest and price volatility. The stock is currently trading at $169.08.

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Key Figures

Accepted abstracts: 3 abstracts Presidential Symposium presentation: October 24, 2026 Pancreatic cancer poster: October 25, 2026 +1 more
Accepted abstracts
3 abstracts
ESMO Congress 2026
Presidential Symposium presentation
October 24, 2026
INTerpath-001 Phase 3 study
Pancreatic cancer poster
October 25, 2026
Phase I study
NSCLC poster
October 26, 2026
INTerpath-014 Phase 3 study

Key Terms

neoantigen therapy, folfirinox, nsclc
3 terms
neoantigen therapy medical
"an investigational mRNA-based individualized neoantigen therapy"
Neoantigen therapy is a personalized cancer treatment that identifies unique mutations on a patient’s tumor and trains the immune system to recognize and attack those specific targets—like creating a custom “wanted” poster for cancer cells. It matters to investors because it promises highly specific, potentially effective therapies but also brings challenges around complex manufacturing, higher development costs, regulatory hurdles and variable market size depending on how broadly a therapy can be applied.
folfirinox medical
"Adjuvant intismeran autogene plus FOLFIRINOX in resectable pancreatic"
FOLFIRINOX is a combination chemotherapy treatment made up of several anti-cancer drugs given together to treat advanced cancers, most often pancreatic cancer. Investors watch it because its effectiveness, side effects and approval or use guidelines influence sales of the component drugs, demand for alternative therapies, hospital treatment patterns and the financial prospects of companies running clinical trials or selling supportive care for these patients—think of it as a widely used multi-drug toolkit whose performance shapes related markets.
nsclc medical
"Completely Resected High-Risk Stage I NSCLC"
NSCLC stands for non-small cell lung cancer, which is the most common type of lung cancer. It develops in the lungs and can spread to other parts of the body, making it serious but often treatable if caught early. Understanding NSCLC helps people recognize the importance of lung health and early detection.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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CAMBRIDGE, MA / ACCESS Newswire / September 21, 2026 / Moderna, Inc. (NASDAQ:MRNA) today announced that three abstracts on intismeran autogene, an investigational mRNA-based individualized neoantigen therapy, have been accepted for presentation at the European Society for Medical Oncology (ESMO) Congress 2026, which will be held October 23-27 in Madrid, Spain.

The presentation details are as follows:

Presidential Symposium:

  • LBA1- INTerpath-001: Phase 3 study of the mRNA-based individualized neoantigen therapy (INT) intismeran autogene (intismeran) plus pembrolizumab (pembro) vs pembro alone for adjuvant treatment of resected stage IIB-IV melanoma (MEL)
    Session Type/Title: Presidential Symposium
    Date & Time: Saturday, October 24, 4:30 PM CEST / 10:30 AM EDT
    Presenter: Georgina V. Long (Sydney, Australia, NSW)

Poster Presentations:

  • Abstract 3151P: Adjuvant intismeran autogene plus FOLFIRINOX in resectable pancreatic ductal adenocarcinoma: results from a phase I study
    Session Type/Title: Poster - Pancreatic cancer
    Date & Time: Sunday, October 25, 12:00-12:45 PM CET
    Presenter: David J. Pinato (London, United Kingdom)
  • Abstract 2550TiP: INTerpath-014: A Phase 3 Study of Adjuvant Intismeran Autogene (Intismeran) Plus Subcutaneous Pembrolizumab (Pembro SC) or Intismeran Monotherapy vs Placebo in Completely Resected High-Risk Stage I NSCLC
    Session Type/Title: Poster - NSCLC, early stage
    Date & Time: Monday, October 26, 12:00-12:45 PM CET
    Presenter: Charu Aggarwal (Philadelphia, United States of America)

Intismeran autogene is jointly developed by Moderna and Merck, known as MSD outside of the United States and Canada.

Moderna Investor Event

Moderna will host a live webcast on Saturday, October 24, at 7:00 PM CEST / 1:00 PM EDT. The webcast will be available under "Events and Presentations" in the Investors section of the Moderna website at investors.modernatx.com. A replay of the webcast will be archived on Moderna's website for at least 30 days following the presentation.

About Moderna

Moderna is a pioneer and leader in the field of mRNA medicine. Through the advancement of its technology platform, Moderna is reimagining how medicines are made to transform how we treat and prevent diseases. Since its founding, Moderna's mRNA platform has enabled the development of vaccines and therapeutics across infectious diseases, cancer, rare diseases and more.

With a global team and a unique culture, driven by the company's values and mindsets, Moderna's mission is to deliver the greatest possible impact to people through mRNA medicines. For more information about Moderna, please visit modernatx.com and connect with us on X, Facebook, Instagram, YouTube and LinkedIn.

Moderna Contacts

Media:

Chris Ridley
Vice President, Global Head of Communications
+1 617-800-3651
Chris.Ridley@modernatx.com

Investors:

Lavina Talukdar
Senior Vice President & Head of Investor Relations
+1 617-209-5834
Lavina.Talukdar@modernatx.com

SOURCE: Moderna, Inc.



View the original press release on ACCESS Newswire

FAQ

AI-generated questions and answers. How Rhea-AI works. Not financial advice.

When and where will the Phase 3 INTerpath-001 melanoma data on intismeran autogene be presented?

The INTerpath-001 Phase 3 melanoma study of intismeran autogene plus pembrolizumab versus pembrolizumab alone will be presented in the ESMO 2026 Presidential Symposium on Saturday, October 24, at 4:30 PM CEST / 10:30 AM EDT in Madrid, Spain.

What other cancer indications for intismeran autogene will be discussed at ESMO 2026?

Additional presentations cover a Phase I study of adjuvant intismeran autogene plus FOLFIRINOX in resectable pancreatic ductal adenocarcinoma (poster session on Sunday, October 25, 12:00-12:45 PM CET) and the Phase 3 INTerpath-014 adjuvant study in completely resected high-risk stage I NSCLC (poster session on Monday, October 26, 12:00-12:45 PM CET).

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