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Moderna Reports Second Quarter 2026 Financial Results and Provides Business Updates

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Moderna (NASDAQ:MRNA) reported second quarter 2026 revenue of $145 million, slightly above $142 million a year earlier, with a GAAP net loss of $(782) million and GAAP EPS of $(1.97). Cost of sales fell 22% year over year, R&D declined 7%, and SG&A decreased 6%.

Cash, cash equivalents and investments totaled $6.9 billion at June 30, 2026, before a $950 million litigation payment in July. For 2026, Moderna targets up to 10% revenue growth, has lowered expected cost of sales to $1.7 billion and R&D to $2.9 billion, and now projects year-end cash and investments of $4.7–$5.2 billion.

According to Moderna, commercial progress included a COVID vaccine collaboration in Brazil, an EU joint procurement contract for up to 24 million mRESVIA doses, and multiple regulatory approvals for mRESVIA, mNEXSPIKE and combination vaccine mCOMBRIAX. A U.S. PDUFA date of August 5, 2026 is set for flu vaccine candidates mFLUSIVA and mRNA‑1010, while norovirus candidate mRNA‑1403 did not meet statistical criteria for early success at an interim Phase 3 analysis.

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Positive

  • Revenue $145M in Q2 2026, slightly above $142M in 2025
  • Net loss improved to $(782)M, 5% better year over year
  • Cost of sales -22% year over year to $93M in Q2 2026
  • R&D expenses -7% year over year to $651M in Q2 2026
  • 2026 cost outlook cut: cost of sales to $1.7B, R&D to $2.9B
  • Strong liquidity: $6.9B cash, cash equivalents and investments at June 30, 2026
  • EC contract for up to 24M mRESVIA doses across six EU countries
  • Multiple approvals for mRESVIA, mNEXSPIKE and mCOMBRIAX in key markets
  • Year-end 2026 cash now projected at $4.7–$5.2B, up ~$0.2B

Negative

  • Significant Q2 loss: GAAP net loss $(782)M and EPS $(1.97)
  • High operating cash burn: $(1.156)B net cash used in operations in first half 2026
  • Inventory write-downs $41M and $23M unutilized capacity in Q2 2026
  • Large litigation impact: $0.9B 2026 cost of sales charge and $950M cash payment in July
  • Norovirus candidate setback: mRNA-1403 missed early success criteria at Phase 3 interim analysis
  • Total assets down to $10.96B from $12.34B at December 31, 2025

Market Context

The stock is down -7.0% following this news. Historical earnings event 886876 recorded a -6.61% 24-h...
Analysis

The stock is down -7.0% following this news. Historical earnings event 886876 recorded a -6.61% 24-hour reaction. The current report similarly paired financial updates with a Phase 3 interim setback. Platform data shows Net Selling by insiders, while moderate short positioning adds a documented risk factor.

Key Figures

Q2 Revenue: $145 million GAAP Net Loss: $(0.8) billion GAAP EPS: $(1.97) +5 more
8 metrics
Q2 Revenue $145 million Q2 2026 vs. $142 million in Q2 2025
GAAP Net Loss $(0.8) billion Q2 2026
GAAP EPS $(1.97) Q2 2026 vs. $(2.13) in Q2 2025
2026 Revenue Growth Up to 10% 2026 financial framework
2026 R&D Expense Outlook Approximately $2.9 billion Lowered from approximately $3.0 billion
Year-End Cash and Investments $4.7 to $5.2 billion 2026 projection; improved by approximately $0.2 billion
Litigation Settlement Payment $950 million Paid in July 2026
Norovirus Trial Phase 3 Interim analysis did not meet statistical criteria for early success

Previous Earnings Reports

5 past events · Latest: May 01 (Negative)
Same Type Pattern 5 events
Date Event Sentiment 24h Move Catalyst
May 01 Q1 earnings report Negative -1.2% Net loss, litigation settlement charge, and reduced quarterly cash position
Feb 13 Q4 earnings report Positive +5.3% Revenue growth reiterated alongside expense reductions and pipeline progress
Nov 06 Q3 earnings report Positive +3.3% Approvals, commercial vaccine sales, and improved operating expense outlook
Aug 01 Q2 earnings report Negative -6.6% Revenue guidance reduction and year-over-year revenue decline
May 01 Q1 earnings report Negative -5.3% Quarterly loss and limited revenue alongside cost reduction plans

24h Move is the share-price change in the day after each event; other market factors may also have contributed.

Pattern Detected

Tag-specific earnings reactions were aligned with the direction of the reported earnings developments in all five historical events, with an average move of -0.92%.

Key Terms

gaap, pdufa, vrbpac, interim analysis, +1 more
5 terms
gaap financial
"GAAP net loss of $(0.8) billion and GAAP EPS of $(1.97)"
GAAP, or Generally Accepted Accounting Principles, are a set of standardized rules and guidelines that companies follow when preparing their financial statements. They ensure consistency, transparency, and comparability across different companies, making it easier for investors to understand and compare financial information accurately. This helps investors make informed decisions based on trustworthy and uniform financial reports.
View in glossary
pdufa regulatory
"ahead of an August 5 Prescription Drug User Fee Act (PDUFA) goal date"
PDUFA is the Prescription Drug User Fee Act, the U.S. law under which drug companies pay fees that fund the FDA's review of new medicines. In company news the term usually appears as the PDUFA date, the target deadline by which the FDA aims to decide on a drug application; that date tells investors when to expect the approval or rejection decision for the product.
vrbpac regulatory
"Vaccines and Related Biological Products Advisory Committee (VRBPAC)"
The Vaccines and Related Biological Products Advisory Committee (VRBPAC) is an independent group of external experts that evaluates vaccine and other biological product data and advises regulators on safety, effectiveness and approval decisions. Investors watch VRBPAC meetings like a public safety review board: a favorable recommendation can speed regulatory clearance and reduce uncertainty, while concerns or negative feedback can delay approval, affect future sales forecasts and change a company’s stock outlook.
interim analysis medical
"did not meet statistical criteria for early success at the Phase 3 interim analysis"
An interim analysis is an early review of a project or process before it is fully completed. For investors, it provides a snapshot of progress or performance, helping to identify whether things are on track, need adjustment, or should be stopped early. Think of it as a progress report that can influence decisions before the final outcome is known.
registrational study medical
"mRNA-3927, is in a registrational study and target enrollment has been reached"
A registrational study is a late-stage clinical trial designed to give the government regulators the evidence they need to decide whether a drug, therapy, or medical device can be approved for sale. Think of it as the final exam or road test for a medical product: its results largely determine whether the product can reach the market, which directly affects potential revenue, company valuation, and investor risk.

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Reports second quarter revenue of $0.1 billion, GAAP net loss of $(0.8) billion and GAAP EPS of $(1.97)

Reiterates plan to deliver up to 10% revenue growth in 2026

Improves 2026 GAAP operating expense outlook by approximately $0.2 billion from previous estimate and improves expected 2026 year-end cash balance to $4.7 - 5.2 billion

Anticipates potential approval of Moderna's fifth product with the August 5th PDUFA date for mFLUSIVA, the Company's seasonal influenza vaccine candidate

Announces that mRNA-1403, Moderna's norovirus vaccine candidate, did not meet statistical criteria for early success at the Phase 3 interim analysis and the Company is preparing to enroll an additional cohort

CAMBRIDGE, MA / ACCESS Newswire / July 31, 2026 / Moderna, Inc. (NASDAQ:MRNA) today reported financial results and provided business updates for the second quarter of 2026.

"The second quarter marked another period of strong execution for Moderna as we advanced our pipeline and strengthened our financial profile with an improved 2026 operating expense outlook," said Stéphane Bancel, Chief Executive Officer of Moderna. "In the second half of 2026, we are preparing for the potential approval of mFLUSIVA in the U.S., which would be our fifth approved product, and continue to anticipate important pivotal readouts for our intismeran in melanoma and propionic acidemia programs."

Commercial Updates

During the second quarter, Moderna continued to advance its multi-year revenue growth strategy by executing on strategic partnerships and key approvals. In Brazil, a collaboration was signed with a local manufacturer in support of a supply agreement for COVID vaccines. In the EU, the Company signed a joint procurement contract with the European Commission on behalf of six countries for up to 24 million doses of mRESVIA®. Moderna also received regulatory approvals in Australia and Mexico for mRESVIA and in Japan and Taiwan for mNEXSPIKE®, and its investigational seasonal influenza vaccine, mFLUSIVA®, received a unanimous recommendation from the Vaccines and Related Biological Products Advisory Committee (VRBPAC) ahead of an August 5 Prescription Drug User Fee Act (PDUFA) goal date in the U.S.

Second Quarter 2026 Financial Results

Revenue: Total revenue for the second quarter of 2026 was $145 million, compared to $142 million in the same period in 2025. Lower COVID vaccine sales in the U.S. and South America were offset by deliveries in the United Kingdom under a long-term strategic government partnership and higher stand-ready manufacturing and collaboration revenue. Revenue was $87 million in the U.S. and $58 million in international markets.

Cost of Sales: Cost of sales for the second quarter of 2026 was $93 million, including $41 million of inventory write-downs, $23 million of unutilized manufacturing capacity costs, and $11 million of third-party royalties. Cost of sales decreased by 22% compared to the same period in 2025, primarily reflecting lower unutilized manufacturing capacity costs resulting from continued manufacturing productivity improvements and operational efficiencies.

Research and Development Expenses: Research and development expenses for the second quarter of 2026 were $651 million, a 7% decrease compared to the same period in 2025. The decrease was primarily driven by lower clinical development costs following the wind-down of several late-stage programs.

Selling, General and Administrative Expenses: Selling, general and administrative expenses for the second quarter of 2026 were $216 million, a 6% decrease compared to the same period in 2025. The decrease reflected continued discipline across the organization.

Income Taxes: Income tax provisions for both periods were not material, as the Company continues to maintain a global valuation allowance against most of its deferred tax assets.

Net Loss: Net loss was $(0.8) billion for the second quarter of 2026, an improvement of $43 million, or 5%, compared to the second quarter of 2025.

Loss Per Share: Loss per share was $(1.97) for the second quarter of 2026, compared to loss per share of $(2.13) for the second quarter of 2025.

Cash Position: Cash, cash equivalents and investments as of June 30, 2026, were $6.9 billion, compared to $7.5 billion as of March 31, 2026. The decrease primarily reflected cash used to fund operations, continued investment in research and development and advancement of the Company's pipeline. The Company subsequently paid $950 million in July 2026 related to the litigation settlement announced in the first quarter of 2026.

2026 Financial Framework

Revenue: The Company is targeting up to 10% growth from 2025 revenue and expects 2026 revenue split to be approximately 50% U.S. and approximately 50% international. Moderna expects approximately 55% of its second half 2026 revenue to be recognized in the third quarter.

Cost of Sales: Cost of sales for 2026 is expected to be approximately $1.7 billion, lowered from approximately $1.8 billion, and including the $0.9 billion non-recurring litigation settlement charge.

Research and Development Expenses: Research and development expenses for 2026 are now anticipated to be approximately $2.9 billion, lowered from approximately $3.0 billion.

Selling, General and Administrative Expenses: Selling, general and administrative expenses for 2026 are projected to be approximately $1.0 billion.

Income Taxes: The Company expects its full-year tax expense to be negligible.

Capital Expenditures: Capital expenditures for 2026 are expected to be $0.2 to $0.3 billion.

Cash and Investments: Year-end cash and investments for 2026 are now projected to be $4.7 to $5.2 billion, an improvement of approximately $0.2 billion. This excludes any further drawdowns from the Company's remaining $0.9 billion available under its credit facility.

Recent Progress and Upcoming Late-Stage Pipeline Milestones

Infectious disease vaccines:

  • Seasonal flu + COVID vaccine: Moderna has received European Commission marketing authorization for mCOMBRIAX in the EU and its mRNA-1083 regulatory filings are under review in Japan, Canada and Australia. The Company is awaiting further guidance from the U.S. FDA on refiling the submission for its flu plus COVID combination vaccine.

  • Seasonal flu vaccine: The Company's mRNA-1010 regulatory filings are under review in Europe, Canada and Australia and potential approvals are expected to begin in 2026. The U.S. FDA has assigned a PDUFA date for mRNA-1010 of August 5, 2026

  • Norovirus vaccine: Moderna's Phase 3 safety and efficacy study of mRNA-1403 did not meet statistical criteria for early success at the Phase 3 interim analysis. The trial is ongoing and remains blinded as the Company works toward enrolling an additional cohort.

Oncology therapeutics:

  • Intismeran autogene: The Company is advancing mRNA-4157 in collaboration with Merck, with nine total Phase 2 and Phase 3 clinical trials underway across multiple tumor types including melanoma, non-small cell lung cancer (NSCLC), bladder cancer and renal cell carcinoma. This includes the Phase 3 study of intismeran as monotherapy and in combination with KEYTRUDA QLEX for the treatment of high-risk Stage 1 NSCLC announced last quarter.

    Fully enrolled studies include a Phase 3 adjuvant melanoma, a Phase 2 adjuvant renal cell carcinoma, and a Phase 2 adjuvant muscle invasive bladder cancer. Moderna expects Phase 3 adjuvant melanoma data potentially in 2026.

    The Company recently presented positive five-year Phase 2b adjuvant melanoma data at the 2026 American Society of Clinical Oncology (ASCO) Annual Meeting, which showed a sustained benefit with intismeran in combination with KEYTRUDA, reducing the risk of recurrence or death by 49% compared to KEYTRUDA alone.

  • mRNA-4359: Moderna's Phase 1/2 study of mRNA-4359, an investigational wholly-owned cancer antigen therapy, is ongoing. The Phase 2 portion of the study includes cohorts in first-line metastatic melanoma, second-line+ metastatic melanoma and first-line metastatic NSCLC.

Rare disease therapeutics:

  • Propionic acidemia (PA) therapeutic: The Company's PA candidate, mRNA-3927, is in a registrational study and target enrollment has been reached. Moderna expects potential data in 2026.

  • Methylmalonic acidemia (MMA) therapeutic: The Company deferred its decision on a pivotal trial for mRNA-3705 until PA registrational data readout.

Moderna Corporate Updates

  • Appointed Ester Banque to Chief Commercial Officer of Moderna, effective June 15, 2026.

  • Appointed Michael McDonnell, former Chief Financial Officer of Biogen, to Moderna's Board of Directors, effective July 8, 2026.

Company Accolades

  • Moderna was ranked no. 1 by TIME on its list of the World's Most Impactful Companies.

Key 2026 Investor and Analyst Event Dates

  • Analyst Day: November 12

Investor Call and Webcast Information

Moderna will host a live conference call and webcast at 8:00 a.m. ET on July 31, 2026. To access the live conference call via telephone, please register at the link below. Once registered, dial-in numbers and a unique pin number will be provided. A live webcast of the call will also be available under "Events and Presentations" in the Investors section of the Moderna website.

The archived webcast will be available on Moderna's website approximately two hours after the conference call and will be available for one year following the call.

About Moderna

Moderna is a pioneer and leader in the field of mRNA medicine. Through the advancement of its technology platform, Moderna is reimagining how medicines are made to transform how we treat and prevent diseases. Since its founding, Moderna's mRNA platform has enabled the development of vaccines and therapeutics across infectious diseases, cancer, rare diseases and more.

With a global team and a unique culture, driven by the company's values and mindsets, Moderna's mission is to deliver the greatest possible impact to people through mRNA medicines. For more information about Moderna, please visit modernatx.com and connect with us on X, Facebook, Instagram, YouTube and LinkedIn.

MODERNA, INC.
CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS
(Unaudited, in millions, except per share data)


Three Months Ended June 30,

Six Months Ended June 30,


2026

2025

2026

2025

Revenue:





Net product sales

$

94

$

114

$

446

$

200

Other revenue1

51

28

88

50

Total revenue

145

142

534

250

Operating expenses:
Cost of sales

93

119

1,048

209

Research and development

651

700

1,300

1,556

Selling, general and administrative

216

230

389

442

Total operating expenses

960

1,049

2,737

2,207

Loss from operations

(815

)

(907

)

(2,203

)

(1,957

)

Interest income

67

81

139

171

Other (expense) income, net

(19

)

8

(37

)

4

Loss before income taxes

(767

)

(818

)

(2,101

)

(1,782

)

Provision for income taxes

15

7

24

14

Net loss

$

(782

)

$

(825

)

$

(2,125

)

$

(1,796

)

Net loss per share
Basic and Diluted

$

(1.97

)

$

(2.13

)

$

(5.36

)

$

(4.64

)

Weighted average common shares used in calculation of net loss per share
Basic and Diluted

398

388

396

387

1Includes grant, collaboration, licensing and royalty, and stand-ready manufacturing revenue.

MODERNA, INC.
CONDENSED CONSOLIDATED BALANCE SHEETS
(Unaudited, in millions)


June 30,

December 31,


2026

2025

Assets



Current assets:



Cash and cash equivalents

$

1,723

$

2,595

Investments

3,415

3,204

Accounts receivable, net

17

184

Inventory

280

153

Prepaid expenses and other current assets

380

408

Total current assets

5,815

6,544

Investments, non-current

1,772

2,336

Property, plant and equipment, net

2,059

2,134

Right-of-use assets, operating leases

697

719

Other non-current assets

618

605

Total assets

$

10,961

$

12,338

Liabilities and Stockholders' Equity
Current liabilities:
Accounts payable

$

167

$

317

Accrued liabilities

1,909

1,386

Deferred revenue

295

99

Other current liabilities

163

185

Total current liabilities

2,534

1,987

Deferred revenue, non-current

147

153

Operating lease liabilities, non-current

638

653

Financing lease liabilities, non-current

6

20

Long-term debt

591

590

Other non-current liabilities

284

285

Total liabilities

4,200

3,688

Stockholders' equity:
Additional paid-in capital

1,644

1,382

Accumulated other comprehensive income

19

45

Retained earnings

5,098

7,223

Total stockholders' equity

6,761

8,650

Total liabilities and stockholders' equity

$

10,961

$

12,338

MODERNA, INC.
CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS
(Unaudited, in millions)


Six Months Ended June 30,


2026

2025

Operating activities



Net loss

$

(2,125

)

$

(1,796

)

Adjustments to reconcile net loss to net cash used in operating activities:
Stock-based compensation

224

245

Depreciation and amortization

122

96

Amortization/accretion of investments

(21

)

(37

)

Loss on equity investments, net

2

8

Other non-cash items

10

36

Changes in assets and liabilities:
Accounts receivable, net

167

310

Prepaid expenses and other assets

70

(150

)

Inventory

(126

)

(122

)

Right-of-use assets, operating leases

21

19

Accounts payable

(128

)

(203

)

Accrued liabilities

475

(395

)

Deferred revenue

195

68

Operating lease liabilities

(15

)

(10

)

Other liabilities

(27

)

(25

)

Net cash used in operating activities

(1,156

)

(1,956

)

Investing activities
Purchases of marketable securities

(1,904

)

(3,059

)

Proceeds from maturities of marketable securities

1,442

3,424

Proceeds from sales of marketable securities

814

1,059

Purchases of property, plant and equipment

(99

)

(120

)

Purchase of intangible asset

-

(10

)

Net cash (used in) provided by investing activities

253

1,294

Financing activities
Proceeds from issuance of common stock through equity plans

42

17

Tax payments related to net share settlements on equity awards

(4

)

(1

)

Changes in financing lease liabilities

(7

)

(3

)

Net cash provided by financing activities

31

13

Effect of changes in exchange rates on cash and cash equivalents

(1

)

1

Net decrease in cash, cash equivalents and restricted cash

(873

)

(648

)

Cash, cash equivalents and restricted cash, beginning of year

2,597

1,929

Cash, cash equivalents and restricted cash, end of period

$

1,724

$

1,281

 

Spikevax®, mRESVIA®, mNEXSPIKE®, mCOMBRIAX® and mFLUSIVA® are registered trademarks of Moderna.

Forward-Looking Statements

This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995, as amended, including statements regarding: Moderna's 2026 financial framework, including its plan to deliver up to 10% revenue growth and GAAP operating expense reductions, and its projected year-end cash balance; Moderna's multi-year revenue growth strategy, including geographic expansion and new product approvals; Moderna's continued cost discipline; Moderna's international strategic partnerships; expectations regarding mRNA-4157 Phase 3 adjuvant melanoma data in 2026; the potential of intismeran as monotherapy and in combination with KEYTRUDA QLEX; the potential of Moderna's oncology portfolio; pending and anticipated regulatory filings and potential approvals, including timing of approvals; Moderna's PDUFA date in the U.S. for mRNA-1010 and the potential product approval of mFLUSIVA; enrollment of an additional cohort for mRNA-1403; and anticipated progress and milestones for Moderna's pipeline programs, including potential near-term data and other catalysts. In some cases, forward-looking statements can be identified by terminology such as "will," "may," "should," "could," "expects," "intends," "plans," "aims," "anticipates," "believes," "estimates," "predicts," "potential," "continue," or the negative of these terms or other comparable terminology, although not all forward-looking statements contain these words. The forward-looking statements in this press release are neither promises nor guarantees, and you should not place undue reliance on these forward-looking statements because they involve known and unknown risks, uncertainties, and other factors, many of which are beyond Moderna's control and which could cause actual results to differ materially from those expressed or implied by these forward-looking statements. These risks, uncertainties, and other factors include, among others, those risks and uncertainties described under the heading "Risk Factors" in Moderna's Annual Report on Form 10-K for the fiscal year ended December 31, 2025, filed with the U.S. Securities and Exchange Commission (SEC), and in subsequent filings made by Moderna with the SEC, which are available on the SEC's website at www.sec.gov. Except as required by law, Moderna disclaims any intention or responsibility for updating or revising any forward-looking statements contained in this press release in the event of new information, future developments or otherwise. These forward-looking statements are based on Moderna's current expectations and speak only as of the date of this press release.

###

Moderna Contacts

Media:
Chris Ridley
Vice President, Head of Global Communications
+1 617-800-3651
Chris.Ridley@modernatx.com

Investors:
Lavina Talukdar
Senior Vice President & Head of Investor Relations
+1 617-209-5834
Lavina.Talukdar@modernatx.com

SOURCE: Moderna, Inc.



View the original press release on ACCESS Newswire

FAQ

How did Moderna (MRNA) perform financially in Q2 2026?

Moderna reported Q2 2026 revenue of $145 million and a GAAP net loss of $(782) million, or $(1.97) per share. According to Moderna, lower COVID vaccine sales were offset by UK deliveries, stand-ready manufacturing revenue and collaboration income.

What 2026 revenue guidance did Moderna (MRNA) provide with its Q2 2026 results?

Moderna is targeting up to 10% revenue growth in 2026 compared with 2025 revenue. According to Moderna, it expects the 2026 revenue mix to be about 50% U.S. and 50% international, with roughly 55% of second-half revenue recognized in the third quarter.

What is Moderna’s 2026 cost and cash outlook after Q2 2026?

Moderna now expects 2026 cost of sales of about $1.7 billion and R&D expenses of about $2.9 billion. According to Moderna, it projects year-end 2026 cash and investments of $4.7–$5.2 billion, excluding any further credit facility drawdowns.

What are the key regulatory milestones for Moderna’s flu vaccines in 2026?

The U.S. FDA assigned an August 5, 2026 PDUFA date for seasonal flu candidate mRNA-1010 and for mFLUSIVA. According to Moderna, mRNA-1010 filings are also under review in Europe, Canada and Australia, with potential approvals expected to begin in 2026.

What happened with Moderna’s norovirus vaccine candidate mRNA-1403?

Moderna’s Phase 3 study of mRNA-1403 did not meet statistical criteria for early success at its interim analysis. According to Moderna, the trial remains blinded and the company is preparing to enroll an additional cohort to continue the registrational study.

How strong is Moderna’s balance sheet after Q2 2026?

Moderna held $6.9 billion in cash, cash equivalents and investments at June 30, 2026. According to Moderna, this preceded a $950 million litigation settlement payment in July and it still expects year-end 2026 cash and investments of $4.7–$5.2 billion.

What late-stage oncology and rare disease milestones did Moderna highlight in Q2 2026?

Moderna is running nine Phase 2/3 trials of intismeran (mRNA-4157) with Merck, including fully enrolled melanoma and renal cell carcinoma studies. According to Moderna, it expects potential Phase 3 melanoma data and registrational propionic acidemia data from mRNA-3927 in 2026.