Mersana Therapeutics Inc Stock Price, News & Analysis

Mersana Therapeutics (NASDAQ:MRSN) presented promising preclinical data for their antibody-drug conjugates (ADCs) XMT-1660 and XMT-2056 at the Virtual 2021 American Association for Cancer Research Annual Meeting. XMT-1660, targeting B7-H4, demonstrated superior efficacy in triple-negative breast cancer models, while XMT-2056 showed enhanced therapeutic potential as a STING-agonist ADC. Both candidates are set to advance into clinical trials in early 2022, reinforcing Mersana's commitment to develop innovative cancer therapies.

Mersana Therapeutics (NASDAQ:MRSN) announced a conference call and webcast on April 16, 2021, at 8:00 a.m. ET, to discuss the NaPi2b biomarker cutoff and the commercial diagnostic development for its UPLIFT registration strategy in platinum-resistant ovarian cancer. The company aims to deliver a robust and predictive commercial diagnostic assay. Interested parties can access the call via phone or through a live webcast on Mersana's website.

Mersana Therapeutics (NASDAQ:MRSN) has initiated patient dosing in its UPLIFT trial, focusing on upifitamab rilsodotin (UpRi) for platinum-resistant ovarian cancer. This registration strategy aims to evaluate UpRi's safety and efficacy in patients with limited treatment options. The trial expects to enroll approximately 100 patients with high NaPi2b expression and up to 180 overall. The primary endpoint is the objective response rate in the high NaPi2b population. UpRi has shown promising activity without severe side effects, according to the company's executives.

Mersana Therapeutics (MRSN) announced the publication of two key manuscripts in Molecular Cancer Therapeutics, detailing the preclinical development of its Dolaflexin ADC platform and XMT-1536 (UpRi). The first manuscript highlights Dolaflexin's innovative features, including a high drug-antibody ratio and a controlled bystander effect, aimed at improving efficacy while minimizing common toxicities. The second manuscript discusses UpRi's targeted action against human NaPi2b, demonstrating promising preclinical results in ovarian and lung cancers. Mersana plans to advance its clinical studies, including UPLIFT and UPGRADE, in 2021.

Mersana Therapeutics (Nasdaq: MRSN) appointed Allene Diaz to its board of directors on March 11, 2021. Diaz brings over 30 years of pharmaceutical experience, previously holding positions at GlaxoSmithKline, Tesaro, and Merck KGaA. Her expertise in strategic product planning and commercialization is expected to bolster Mersana's focus on developing UpRi, a therapy for ovarian cancer. The company emphasizes its commitment to delivering innovative antibody-drug conjugates (ADCs) targeting areas of high unmet medical need.

Mersana Therapeutics (NASDAQ:MRSN) announced its participation in the Virtual 2021 American Association for Cancer Research Annual Meeting, presenting data on three antibody-drug conjugates (ADCs) targeting cancers. The posters include findings on XMT-1660, a novel ADC for breast cancer, and XMT-2056, a well-tolerated ADC that activates the STING pathway to induce anti-tumor immunity. The presentations, scheduled for April 10, 2021, highlight Mersana's commitment to developing effective therapies for cancers with high unmet need.

Mersana Therapeutics (NASDAQ:MRSN) reported its financial results for Q4 and FY 2020, ending with $255 million in cash. The company is set to initiate UPLIFT, a registration study for Upifitamab rilsodotin (UpRi) in platinum-resistant ovarian cancer, in Q1 2021. Key achievements included an objective response rate (ORR) of 32% in the higher NaPi2b population from January 2021 data, indicating potential for a meaningful benefit in heavily pretreated patients. The net loss for Q4 2020 was $28.8 million, compared to $16.2 million in Q4 2019.

Mersana Therapeutics, Inc. (NASDAQ:MRSN) announced a conference call on February 26, 2021, at 8:00 a.m. ET to report its financial results for Q4 and FY 2020. The call will provide business updates, focusing on its antibody-drug conjugate pipeline. Mersana's lead candidate, upifitamab rilsodotin (XMT-1536), is in a Phase 1 study for ovarian cancer and NSCLC adenocarcinoma. The company is also advancing XMT-1592 and early-stage programs targeting various cancers using its proprietary ADC platforms.

Mersana Therapeutics, Inc. (NASDAQ:MRSN) will participate in a fireside chat on February 24, 2021, at 10:00 a.m. ET, during the SVB Leerink 10th Annual Global Healthcare Conference. Investors can access a live webcast on the company’s website, with an archived replay available for 90 days post-event. Mersana focuses on developing antibody-drug conjugates (ADCs) for cancer treatment, with lead candidate upifitamab rilsodotin (XMT-1536) in clinical studies for ovarian cancer and NSCLC. The company also has several promising ADCs in its pipeline targeting specific tumor types.