Merus Stock Price, News & Analysis

Merus N.V. (Nasdaq: MRUS) reported its financial results for Q4 and FY 2020, highlighting advancements in its clinical programs. The clinical update for zenocutuzumab is expected in 2Q 2021, focusing on NRG1 fusion cancers, with over 30 patients involved. Collaboration with Loxo Oncology has resulted in $60 million of upfront payments and equity investment. The company aims to extend its financial runway to at least 2H 2024, supported by cash reserves of $207.8 million. R&D expenses increased by $14.4 million, primarily due to escalating costs for zenocutuzumab.

Merus N.V. (Nasdaq: MRUS) has announced its participation in the AACR 2021 Annual Meeting, presenting preclinical data on its innovative multispecific antibodies, zenocutuzumab and MCLA-129. These presentations, scheduled for April 10-15 and May 17-21, 2021, will focus on the effectiveness of zenocutuzumab against tumors driven by NRG1 gene fusions and MCLA-129's role in impairing NSCLC tumor growth. The company aims to showcase the potential of its Biclonics® technology in cancer therapies.

Merus N.V. (Nasdaq: MRUS), a clinical-stage oncology company, announced that CEO Bill Lundberg, M.D., will participate in a fireside chat at the 33rd Annual Roth Conference on March 15, 2021, at 2:00 p.m. ET. The event will be accessible via a live webcast on the Company’s Investors page, with an archived version available for a limited time afterward.

Merus is known for developing innovative, full-length multispecific antibodies, branded as Biclonics® and Triclonics®, which have shown promising features in clinical studies.

On February 1, 2021, Merus N.V. (Nasdaq: MRUS), a clinical-stage oncology company, announced that CEO Bill Lundberg will participate in upcoming investor conferences. Key events include the Guggenheim Healthcare Talks 2021 Oncology Days on February 12, LifeSci Partners Precision Oncology Day on February 17, and the 2021 SVB Leerink Global Healthcare Conference on February 26. Webcasts of the presentations will be accessible via the Company’s Investors page, with archived versions available for a limited time.

Merus N.V. (MRUS) announced an underwritten public offering of 4,848,485 common shares at $24.75 each, aiming for gross proceeds of approximately $120 million. The offering is expected to close around January 25, 2021, pending customary conditions. Merus plans to use the funds for advancing clinical development, preclinical research, and general corporate purposes. The offering includes an option for underwriters to purchase an additional 727,272 shares. Jefferies LLC and SVB Leerink LLC are leading the offering, with a registration statement filed with the SEC for compliance.

Merus N.V. (Nasdaq: MRUS) has announced a proposed underwritten public offering of up to $60 million of its common shares, with an additional $9 million option for underwriters. The offering is subject to market conditions and aims to support the clinical development of its innovative multispecific antibodies, along with preclinical research and working capital needs. Jefferies LLC and SVB Leerink LLC are the joint book-running managers. The shares will be offered under a shelf registration statement filed with the SEC.

Loxo Oncology at Lilly and Merus N.V. announced a collaboration to develop CD3-engaging bispecific antibody therapies. Merus will lead discovery, with Lilly handling development and commercialization. Merus receives $40 million upfront, $20 million equity investment, and up to $1.6 billion in potential milestones for up to three products. This partnership enhances Loxo's biologics strategy. The transaction aligns with Lilly's financial guidance, with no change to 2021 non-GAAP earnings per share expected.

Merus N.V. (MRUS) announced collaborations with key medical organizations in the Netherlands and Japan to promote the eNRGy trial, focusing on identifying NRG1 fusions in cancer patients. The initiative includes support for next-generation sequencing for pancreatic adenocarcinoma patients in both countries. Erasmus MC in the Netherlands and the National Cancer Center in Japan will raise awareness and facilitate screening. The eNRGy trial evaluates zenocutuzumab’s safety and efficacy in treating NRG1+ cancers, aiming to advance patient enrollment in this Phase 1/2 study.

Merus N.V. (MRUS) announced the presentation of clinical data from its Phase 1 dose escalation study of MCLA-158 at the ASCO 2021 Gastrointestinal Cancers Symposium, scheduled from January 15-17, 2021. MCLA-158, a bispecific antibody targeting EGFR and LGR5, was reported to be well-tolerated, successfully reaching the recommended phase 2 dose. The ongoing dose expansion phase includes patient enrollment for gastric and other non-CRC cancers, indicating progress in their clinical development efforts.