Satellos to Host Virtual KOL Event on SAT-3247 in Duchenne Muscular Dystrophy
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key opinion leader (KOL)technical
A key opinion leader (KOL) is a person who is highly trusted and influential in a specific area, like fashion, technology, or health. Their opinions can shape what many people think or buy, making them important for brands or companies that want to reach a wide audience.
duchenne muscular dystrophy (DMD)medical
Duchenne muscular dystrophy (DMD) is a severe, inherited disorder caused by a faulty gene that leaves muscle cells unable to maintain their structure, leading to progressive muscle weakness and loss of mobility, often beginning in childhood. Investors care because DMD is a high unmet-need condition that drives demand for new therapies; successful drugs can command premium pricing and regulatory incentives, while clinical trial failures or safety issues can sharply affect companies and their stock value.
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A pill or liquid medicine made from small chemical compounds that you take by mouth to affect specific biological targets inside the body; think of each compound as a tiny key designed to fit a particular molecular lock. Investors care because these therapies are typically easier and cheaper to manufacture, scale, store, and distribute than complex biologic treatments, and they often follow clearer regulatory paths and market dynamics that affect development cost, pricing, and potential revenue.
aak1medical
AAK1 is a human gene that makes a protein acting like a traffic controller inside cells, helping move and sort molecules into and out of the cell. Investors care because drugs that block or modify AAK1 can change how cells handle infections or neurological signals, so evidence that a therapy affects AAK1 can influence the value of biotech pipelines, clinical trial prospects, and future regulatory or commercial outcomes.
muscle stem-cell signalingmedical
Muscle stem-cell signaling is the set of chemical and physical messages that tell dormant muscle stem cells when to wake up, multiply, repair damage or stay idle — like traffic signals directing repair crews to a damaged road. Investors care because drugs, biologics or devices that change those messages can restore strength in muscle-wasting conditions, creating large therapeutic and commercial opportunities tied to clinical trial and regulatory outcomes.
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Phase 1a/b is an early-stage clinical trial that tests a new drug or medical treatment in people to assess safety, find the right dose, and look for early signs it might work. For investors it matters because positive phase 1a/b results lower scientific and regulatory uncertainty and unlock value by advancing the program to larger trials, while negative results can sharply reduce a treatment’s commercial prospects—similar to passing or failing an initial safety inspection before mass production.
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Phase 2 is the mid-stage clinical trial where a new drug or treatment is tested in a larger group of patients to see if it works and to keep checking safety after initial human testing. Think of it as a field test that proves whether a product actually delivers its promised benefit. Investors watch Phase 2 closely because its results strongly influence a medicine’s chances of reaching the market, the size of its potential sales, and the company’s valuation.
TORONTO--(BUSINESS WIRE)--
Satellos Bioscience Inc. (NASDAQ: MSLE, TSX: MSCL) (“Satellos” or the “Company”), a clinical-stage biotechnology company developing life-improving medicines to treat degenerative muscle diseases, today announced that it will host a virtual key opinion leader (KOL) event on Tuesday, Feb. 24, 2026, at 3:30 p.m. ET, featuring Kevin M. Flanigan, MD, the Wolfe Foundation Endowed Chair in Neuromuscular Research at Nationwide Children’s Hospital and professor of pediatrics and neurology at The Ohio State University College of Medicine. Dr. Flanigan will join company management to discuss the unmet need and current treatment landscape for Duchenne muscular dystrophy (DMD). Interested participants may register here.
The event will provide an overview of Satellos' SAT-3247, an oral small molecule therapy designed to restore natural muscle repair and regeneration in DMD and related conditions. SAT-3247 targets AAK1, a protein involved in muscle stem-cell signaling, a process that is disrupted in DMD due to the absence of dystrophin. The session will review results from the completed Phase 1a/b clinical trial in healthy volunteers and adults with DMD; outline TRAILHEAD, an open-label study in adult participants; and share updates on BASECAMP, an ongoing Phase 2 pediatric study.
ABOUT KEVIN M. FLANIGAN, MD
Kevin M. Flanigan, MD, is the Director of the Center for Gene Therapy at the Abigail Wexner Research Institute of Nationwide Children’s Hospital (NCH), where he holds the Robert F. & Edgar T. Wolfe Foundation Endowed Chair in Neuromuscular Research. Dr. Flanigan trained in Neurology and Neuromuscular Disease at the Johns Hopkins Hospital, followed by a post-doctoral fellowship in Human Molecular Biology and Genetics at the University of Utah. After 14 years on the faculty in Utah, he joined NCH in 2009. He is currently the director of the NCH P50-funded Wellstone Muscular Dystrophy Specialized Research Center and is a Professor of Pediatrics and Neurology at Ohio State University. His laboratory work is directed toward the identification of genetic modifiers of disease severity in the dystrophinopathies, and toward the molecular characterization and treatment of neuromuscular diseases, using both gene replacement and RNA-modifying therapies. His lab has a particular interest in AAV-delivered U7snRNAs modified to target specific exons in the DMD gene, which has led to a first-in-human clinical trial. He is an experienced clinical trialist and has conducted multiple clinical trials of gene transfer therapies in DMD, as well as the childhood neurodegenerative disorders mucopolysaccharidosis types 3A and 3B
ABOUT SAT-3247
SAT-3247 is a proprietary, oral, small molecule drug candidate being developed by Satellos as a novel approach to regenerating skeletal muscle lost in Duchenne muscular dystrophy (DMD) and other degenerative muscle diseases or injury conditions. Satellos is advancing SAT-3247 as a potential treatment for DMD that is independent of dystrophin and applicable regardless of exon mutation status, with ongoing Phase 2 clinical studies, including TRAILHEAD, an open-label study in adult participants, and BASECAMP, a global, randomized, placebo-controlled study in pediatric participants.
ABOUT SATELLOS BIOSCIENCE INC.
Satellos is a clinical-stage drug development company focused on restoring natural muscle repair and regeneration in degenerative muscle diseases. Through its research, Satellos has developed SAT-3247, a first-of-its-kind, orally administered small molecule drug designed to address deficits in muscle repair and regeneration. SAT-3247 targets AAK1, a key protein that Satellos has identified as capable of helping restore muscle stem-cell signaling, a process that is disrupted in DMD. By addressing the loss of dystrophin-dependent cues, SAT-3247 may re-establish the signals that support effective muscle regeneration. SAT-3247 is currently in clinical development as a potential disease-modifying treatment, initially for DMD. Satellos is also working to identify additional muscle diseases or injury conditions where restoring muscle repair and regeneration may have therapeutic benefit and represent future clinical development opportunities. For more information, visit www.satellos.com.
