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Matinas BioPharma Holdings, Inc. develops biopharmaceutical therapies using its lipid nanocrystal, or LNC, delivery technology. Company updates center on MAT2203, an oral formulation of amphotericin B for invasive fungal infections, along with broader LNC platform applications for intracellular delivery of small molecules and oligonucleotides.
Recurring MTNB news also covers operating and financial results, clinical and regulatory disclosures, governance changes, shareholder ownership activity, capital-structure matters, and NYSE American continued-listing compliance. The company’s announcements connect its drug-development work with board oversight, financing needs, and public-company requirements.
BioNTech and Matinas BioPharma have announced an exclusive research collaboration to enhance mRNA vaccine formulations using Matinas' Lipid Nanocrystal (LNC) Delivery Platform Technology. The partnership aims to explore innovative approaches, including potential oral vaccines. Matinas will receive an upfront access fee and further research funding from BioNTech. Discussions for a licensing agreement for the LNC technology have also begun. This collaboration is viewed as a significant validation for Matinas' delivery platform, potentially benefiting millions through improved vaccine delivery methods.
Matinas BioPharma (MTNB) announced that CEO Jerry Jabbour will present at the 21st Annual Needham Virtual Healthcare Conference on April 13, 2022, at 3:00 p.m. ET. Investors can arrange virtual meetings through the conference coordinator. The presentation will be available via webcast and archived on the company’s website for 90 days. Matinas focuses on advancing its lipid nanocrystal technology for drug delivery, with ongoing clinical trials for MAT2203 and MAT2501, targeting fungal and bacterial infections, respectively.
Matinas BioPharma (NYSE: MTNB) announced that CEO Jerry Jabbour will present at the 2022 Virtual Growth Conference hosted by Maxim Group LLC from March 28-30, 2022. Pre-recorded presentations will be available on-demand. The conference offers insights into Matinas' lipid nanocrystal (LNC) platform technology, which enhances intracellular drug delivery. The company is developing product candidates like MAT2203 for fungal infections and MAT2501 for bacterial infections, with ongoing clinical trials. For more details, visit Matinas' website.
Matinas BioPharma Holdings (MTNB) reported fourth quarter and full year 2021 results, highlighting a net loss of $6.7 million for Q4 and $23.7 million for the year. Enrollment in the EnACT trial's fourth cohort continues, with 15 patients enrolled so far, and topline data expected in Q3 2022. The company plans to expand the trial into a fifth cohort pending FDA approval. They ended 2021 with $49.6 million in cash, sufficient to fund operations into 2023. A new in vivo study for LNC-remdesivir will begin in March 2022, aiming for further advancements in nucleic acid delivery technology.
Matinas BioPharma Holdings (MTNB) will host a conference call on March 8, 2022, at 8:30 a.m. ET to discuss its Q4 and full-year 2021 financial results. Interested participants can call (877) 407-5976 (Toll-Free) or (412) 902-0031 (Toll) and use conference ID 13727084. The live audio webcast will be available on Matinas' website, with an archive lasting 90 days. The company focuses on its lipid nanocrystal (LNC) platform technology, aiming to enhance intracellular delivery of drugs, including MAT2203 and MAT2501, which target serious infections and diseases.
Matinas BioPharma (MTNB) recently announced a successful End of Phase 2 meeting with the FDA regarding its MAT2203 program, which aims to treat invasive fungal infections. The company reported a survival rate of 98% in patients using MAT2203 compared to 88% with standard treatments. MAT2203's NDA submission is anticipated for late 2023, pending additional data from an expanded clinical trial. Financially, Matinas ended 2021 with approximately $49.9 million, sufficient to support operations through 2023. Collaborations with NIAID and Genentech remain promising for continued development.
Matinas BioPharma Holdings, Inc. (NYSE: MTNB) will host a conference call and audio webcast on January 25, 2022, at 8:30 a.m. ET to discuss corporate updates and its 2022 business outlook. The call will include updates on ongoing programs and collaborations. Key product candidates include MAT2203, an oral formulation of amphotericin B in a Phase 2 study for cryptococcal meningitis, and MAT2501, in Phase 1 for NTM lung disease. LYPDISO™, an omega-3 therapy, is also under development. The call can be accessed via their website.
Matinas BioPharma Holdings, Inc. (MTNB) reported that the Data and Safety Monitoring Board (DSMB) has approved the progression to the fourth cohort of the EnACT trial, evaluating MAT2203 for cryptococcal meningitis. The third cohort demonstrated successful antifungal activity above the target threshold, maintaining a strong safety profile. Enrollment for 40 additional patients is anticipated to start in early Q1 2022. MAT2203 aims to be a first-line treatment option, potentially transforming the landscape for invasive fungal infections.
Matinas BioPharma Holdings, Inc. (NYSE: MTNB) has appointed Thomas Hoover as the Chief Business Officer, focusing on business and corporate development. Hoover brings nearly 20 years of biopharmaceutical experience, including previous roles at Millendo Therapeutics and Sunovion. CEO Jerome D. Jabbour expressed confidence in Hoover's ability to advance the company's lipid nanocrystal (LNC) platform during this critical period. Matinas is developing multiple LNC formulations, including MAT2203 for invasive fungal infections and MAT2501 for bacterial infections, and plans to partner further on its omega-3 therapy, LYPDISO.
Matinas BioPharma Holdings (NYSE: MTNB) has been invited to present at the Piper Sandler 33rd Annual Virtual Healthcare Conference from November 29 to December 2, 2021. The company will showcase its innovative lipid nanocrystal (LNC) delivery platform and will hold investor meetings. A pre-recorded presentation will be available on the company’s IR Calendar page starting November 22, 2021, at 10:00 a.m. ET. Additionally, CEO Jerome D. Jabbour will lead a fireside chat at the B. Riley Fall 2021 Growth Biotech Best Ideas Series on November 23, 2021, at 12:30 p.m. ET.