Nanobiotix S.A. Stock Price, News & Analysis

Nanobiotix (NASDAQ: NBTX) has announced the termination of its liquidity contract with Gilbert Dupont, effective December 20, 2022. This decision follows the review of the liquidity account, which held 22,118 shares and €71,489.96 in cash at the time of termination. The company reported a trading volume of 303,404 shares on the buy side and 306,992 shares on the sell side between July and December 2022, indicating active market participation. Despite ending this contract, Nanobiotix continues its focus on developing its lead product, NBTXR3, which has received market authorization in Europe.

Nanobiotix announced its shareholding structure as of November 30, 2022, revealing a total of 34,875,872 shares outstanding. The total number of theoretical voting rights stands at 36,286,699, while the exercisable voting rights are 36,269,556. This disclosure is in compliance with French financial regulations aimed at ensuring transparency in corporate governance. Nanobiotix continues to advance its pipeline of innovative therapeutic options for cancer treatment, leveraging its patented nanoparticle technology.

NANOBIOTIX, a late-stage clinical biotechnology company, announced that its co-founder Laurent Levy and CFO Bart Van Rhijn will participate in a virtual fireside chat at the 5th annual Evercore ISI HealthCONx Conference on December 1, 2022, at 9:15 AM ET / 3:15 PM CET. The chat will be available live on the company's website and archived for 90 days. NANOBIOTIX focuses on enhancing cancer treatment outcomes through its innovative nanoparticle platform, especially targeting head and neck cancers.

Nanobiotix has announced the successful completion of the dose escalation phase in a phase 1 study, evaluating NBTXR3 for patients with locally advanced pancreatic adenocarcinoma. The recommended phase 2 dose was set at 42% of the gross tumor volume, with ongoing recruitment for the expansion phase. Encouraging results include a partial response in one patient and successful local control in another leading to resectability. Safety data and early efficacy findings will be presented at a medical congress in 2023, bolstering confidence in NBTXR3's potential impact against this challenging cancer.

Nanobiotix announced promising results from its phase 1 immunotherapy study (Study 1100) involving NBTXR3 activated by radiotherapy and followed by anti-PD-1 therapy. The study demonstrated feasibility and tolerability, establishing a recommended phase 2 dose at 33% of gross tumor volume. Of 21 evaluable patients, 71.43% showed objective reduction in target lesions, with 42.86% achieving over 30%. Durable systemic disease control was observed in 38.10% of patients for over six months. A registrational phase 3 protocol submission to the FDA is planned for Q1 2023.

Nanobiotix has established the recommended Phase 2 dose for NBTXR3 combined with anti-PD-1 therapy for various cancers. Updated safety and efficacy data from Study 1100 will be presented at the SITC 2022 on November 10. The company has strengthened its scientific advisory board with twelve global medical experts, enhancing its strategic capabilities. As of September 30, 2022, Nanobiotix reported €53.5 million in cash, extending its financial runway into Q1 2024. A debt restructuring agreement with the European Investment Bank has also been finalized.

Nanobiotix announced key updates as of October 31, 2022. The company has 34,875,872 outstanding shares and a total of 36,286,313 theoretical voting rights. The exercisable voting rights amounted to 36,273,212. The firm focuses on innovative therapeutic solutions for cancer treatment, particularly through its lead product NBTXR3, designed to enhance tumor control. These developments underline Nanobiotix's commitment to improving patient outcomes in oncology.

Nanobiotix announced the formation of a Scientific Advisory Board comprising twelve expert oncologists from the US and Europe to support the development of its lead therapeutic candidate, NBTXR3. The board's diverse expertise aims to enhance clinical trial strategies and improve patient care. Leonard Farber, MD, highlighted the necessity of multidisciplinary knowledge for advancing this innovative cancer treatment. NBTXR3 targets solid tumors, with an emphasis on head and neck cancers, leveraging a novel physics-based approach.

Nanobiotix, a late-stage clinical biotechnology company, announced participation in a fireside chat at the Jefferies London Healthcare Conference on November 15, 2022. Laurent Levy, co-founder and chairman, along with Bart Van Rhijn, CFO, will speak at 5:00 PM GMT/12:00 PM ET. The event will be webcast live and available for replay for 30 days. The company is focused on innovative physics-based therapies, including NBTXR3, to improve treatment outcomes in cancer patients, particularly those with head and neck cancers.