Nucana Stock Price, News & Analysis

NuCana plc (NASDAQ: NCNA) announced that Don Munoz, Chief Financial Officer, will hold one-on-one meetings at the Jefferies Healthcare Conference from June 8-10, 2022, in New York, NY. The company focuses on enhancing cancer treatment outcomes through its proprietary ProTide technology, which aims to develop safer and more effective medicines. NuCana’s key product candidates include NUC-3373, in a Phase 1b/2 study for metastatic colorectal cancer, and NUC-7738, in a Phase 1/2 study for advanced solid tumors.

NuCana (NASDAQ: NCNA) reported Q4 and FY 2021 results, revealing a net loss of £40.5 million for the year, higher than the previous year's £30.7 million. As of December 31, 2021, cash reserves were £60.3 million, down from £71 million in Q3 2021. The company plans to launch a Phase 2 study for NUC-3373 in colorectal cancer, aiming for a simplified subsequent Phase 3 study. Additionally, NUC-7738 is advancing into Phase 2, following promising Phase 1 results. NuCana expects a cash runway into 2025, supporting ongoing and upcoming clinical trials.

NuCana plc (NASDAQ: NCNA) announced promising data on its drug NUC-3373 aimed at improving cancer treatment. Presented at the AACR Annual Meeting, the research indicates that NUC-3373 enhances immune response and cell death in colorectal cancer cell lines when combined with nivolumab. Furthermore, NUC-3373 is shown to be more effective than 5-FU, producing higher levels of active metabolites and avoiding its associated toxicities. The company is advancing NUC-3373 into more clinical studies, reinforcing its strategy for treating colorectal cancer.

NuCana plc (NASDAQ: NCNA) has announced the discontinuation of the NuTide:121 study following a futility analysis by its Independent Data Monitoring Committee. Despite a higher objective response rate for Acelarin plus cisplatin, there was no observed overall survival benefit compared to standard treatments. The company remains committed to cancer therapies and is progressing with other candidates, NUC-3373 and NUC-7738, with multiple data readouts expected throughout 2022. The firm emphasizes its robust financial position to support ongoing clinical trials.

NuCana plc (Nasdaq: NCNA) announces participation in two virtual investor conferences. The first is Cowen’s 42nd Annual Healthcare Conference from March 7-9, 2022. The second event is Oppenheimer's 32nd Annual Healthcare Conference on March 16, 2022, at 8:00 AM ET, which will be webcasted live. NuCana focuses on improving cancer treatment through its ProTide technology, with three ProTides in clinical development: Acelarin, NUC-3373, and NUC-7738. Acelarin is in Phase 3 for advanced biliary tract cancer, while NUC-3373 and NUC-7738 are in earlier studies for colorectal and solid tumors.

NuCana plc (NASDAQ: NCNA) announced the completion of patient enrollment for its Phase III NuTide:121 study, which will facilitate a second interim analysis by the second half of 2022. The study is evaluating Acelarin combined with cisplatin against the standard of care, gemcitabine plus cisplatin, for advanced biliary tract cancer. Acelarin's potential for accelerated FDA approval hinges on achieving a statistically significant improvement in the Objective Response Rate (ORR) in interim analyses. The company aims to enroll up to 828 patients in total.

NuCana plc (NASDAQ: NCNA) reported Q3 2021 financial results, noting a cash position of £71.0 million and a net loss of £8.0 million, improving from £8.4 million in Q3 2020.

They completed enrollment of 418 patients for a Phase III study on Acelarin for biliary tract cancer, which may lead to accelerated FDA approval.

The FDA granted Fast Track designation for Acelarin, and positive clinical data for NUC-3373 and NUC-7738 was presented at ESMO 2021.

Several key milestones are anticipated in Q4 2021 and H1 2022.

NuCana plc (NASDAQ: NCNA) announced that CEO Hugh Griffith and CFO Don Munoz will present at the Jefferies 2021 London Healthcare Conference on November 17, 2021, at 4:20 PM GMT. The event will include one-on-one meetings and will be webcast live, with replays available on the company’s website. NuCana focuses on enhancing cancer treatment outcomes using its ProTide technology. Its pipeline includes three ProTides in clinical development, notably Acelarin and NUC-3373, aimed at resistant cancers.

NuCana plc (Nasdaq: NCNA) has appointed Elliott M. Levy, M.D. to its Board of Directors. Dr. Levy, former Senior Vice President at Amgen, brings over 20 years of experience in drug development. He has played a significant role in the creation of 20 approved medicines. His expertise will be crucial as NuCana advances its pipeline of ProTides aimed at improving cancer treatment. The company focuses on transforming nucleoside analogs into better therapies. Dr. Levy expressed excitement about joining NuCana at a pivotal time in its growth.