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NKGen Biotech, Inc. - NKGN STOCK NEWS

Welcome to our dedicated page for NKGen Biotech news (Ticker: NKGN), a resource for investors and traders seeking the latest updates and insights on NKGen Biotech stock.

NKGen Biotech, Inc. (symbol: NKGN) is a progressive biotechnology company dedicated to developing cutting-edge cell therapies aimed at combating neurodegenerative and oncological diseases. The company’s central focus revolves around utilizing activated NK cells, which form a part of the human innate immune response system. These cells have the remarkable ability to selectively identify and eliminate abnormal or diseased cells.

NKGen Biotech’s innovative approach is anchored in a proprietary manufacturing and cryopreservation process that produces SuperNK™ (SNK) cells. These cells exhibit significantly enhanced activity compared to the original population of NK cells. Enhanced parameters include increased cytotoxicity, cytokine production, and activating receptor expression, based on detailed in vitro experiments conducted by NKMAX. One of the notable advantages of SNK cells is their ability to be produced in large quantities and preserved cryogenically without losing their high levels of cytotoxicity.

Recently, NKGen Biotech has achieved significant milestones with its SNK01 trial. Additional Phase 1 data point to clinical activity regarding cognitive function in patients with advanced Alzheimer’s disease, alongside previously disclosed positive effects on amyloid protein and neuroinflammation biomarkers. Dr. Jesse Carr, MD, Medical Director of Behavioral Research Specialists, LLC, has expressed optimism about the trial, highlighting the absence of treatment-related adverse events and noting apparent improvements in patients' cognitive function, daily living activities, and overall quality of life.

For investors and stakeholders, NKGen Biotech represents a beacon of innovation in the biotechnology sector, with its unique approach to developing cell therapies that could potentially redefine the treatment landscape for challenging diseases like Alzheimer’s and various cancers. The company’s robust pipeline, strategic partnerships, and ongoing clinical trials position it as a key player in advancing medical science and therapeutic solutions.

For the latest updates and detailed information, visit the NKGen Biotech website.

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NKGen Biotech (Nasdaq: NKGN) has appointed Dr. Marco Gottardis to its Board of Directors, effective July 11, 2024. Dr. Gottardis will serve on the company's Audit, Compensation, and Nominating and Corporate Governance Committees. He brings extensive experience in biopharmaceuticals and oncology research, having held senior positions at Replay Bio Holdings and Janssen Pharmaceuticals. Dr. Gottardis has a PhD in Human Oncology and has led strategies for novel research platforms and prostate cancer R&D portfolios.

NKGen's CEO, Dr. Paul Y. Song, expressed enthusiasm about Dr. Gottardis joining the board, highlighting his expertise in cell therapy research and development. This appointment is expected to strengthen NKGen's capabilities as they advance their NK cell therapy clinical programs in neurodegenerative diseases and cancer.

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NKGen Biotech presented updated Phase 1 data on its allogeneic NK cell therapy, SNK02, at the 6th Annual Allogeneic Cell Therapies Summit 2024. The therapy avoids lymphodepletion, aiming to preserve immune function and reduce toxicity. In the trial, 6 patients with advanced solid tumors received weekly intravenous doses of SNK02. Four patients completed 8 cycles, with stable disease observed in all. The treatment was generally well-tolerated, with most adverse events being mild. One death occurred but was deemed unrelated to the therapy. Further studies will explore SNK02 in combination with other immunotherapies.

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NKGen Biotech (Nasdaq: NKGN) announced that CEO Paul Y. Song, MD, will present updated Phase 1 data on their SNK02 allogeneic NK cell therapy at the 6th Annual Allogeneic Cell Therapies Summit, June 10-12, 2024, in Boston, MA. The presentation, scheduled for June 12, will highlight the company's cryopreserved allogeneic NK cell therapy platform and the initial Phase 1 results for advanced refractory solid tumors. Dr. Song will discuss the potential benefits of eliminating pre-treatment lymphodepletion, which may reduce toxicity and preserve immune function. Further, the presentation will explore unexpected findings from the SNK02 trial that suggest its use beyond cancer treatment. A copy of the presentation will be available on the company's website post-event.

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NKGen Biotech has announced interim results from its Phase 1 clinical trial of SNK02, an allogeneic NK cell therapy for advanced solid tumors, at the 2024 ASCO Annual Meeting.

The trial showed that SNK02 was well-tolerated and demonstrated a stable disease response in 100% of patients completing 8 treatment cycles. The study involved five patients with refractory solid tumors, averaging four prior lines of therapy, and a median age of 64.

SNK02 did not require lymphodepletion before administration and exhibited some clinical activity as a monotherapy. Adverse events were mostly mild with one Grade 3 event resolving without intervention.

The company plans to continue studying SNK02 in combination with monoclonal antibodies and immune checkpoint inhibitors.

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NKGen Biotech announced that its cryopreserved, enhanced natural killer cell therapy, SNK01, has been cleared to progress into Phase 2 clinical trials for moderate Alzheimer’s disease. The therapy showed clinical benefit and no drug-related adverse events in Phase 1. The Phase 2 trial will involve 30 patients, with 20 receiving SNK01 and 10 receiving a placebo, and will begin in Q2 2024. This trial aims to assess the therapy's efficacy and safety over a full year. Preliminary results are promising, with improvements in cognitive function and daily activities observed.

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NKGen Biotech, a clinical-stage biotech company, will present its autologous NK cell therapy, SNK01, at the 5th International Cell & Gene Therapy China Summit. SNK01, which shows enhanced cytotoxicity and receptor expression, targets neurodegenerative diseases and solid tumors. CEO Paul Y. Song will discuss manufacturing advances and results combining SNK01 with immune checkpoint inhibitors and Erbitux for resistant cancers. The presentation, set for May 23, 2024, will also highlight SNK01's potential against multiple neurodegenerative diseases by improving key protein levels.

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NKGen Biotech, Inc. (NKGN) received FDA clearance for its SNK01 NK cell therapy in Parkinson's disease, advancing its neurodegenerative disease program. The Phase 1/2a clinical trial is set to commence in 2H 2024, with SNK01 showing promising potential in addressing Parkinson's disease through enhanced cytotoxicity and activating receptor expression.

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NKGen Biotech presented updated data on their SNK01 NK cell therapy for neurodegenerative diseases, showcasing positive results in improving cognitive function and reducing neuroinflammation in Alzheimer's patients. The therapy also demonstrated potential applications beyond Alzheimer's, with promising outcomes in Parkinson's disease. The company plans to initiate Phase 2 trials for advanced Alzheimer's and Phase 1 trials for Parkinson's disease in 2024.
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NKGen Biotech, a clinical-stage biotechnology company, will present an interim analysis of a phase I study using cryopreserved non-genetically modified allogeneic natural killer cells at the 2024 ASCO Annual Meeting. The study focuses on patients with advanced solid tumors without lymphodepletion. The ePublication will be available on the company's website.
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NKGen Biotech, Inc. announced that Paul Y. Song, MD, will present details on the NK cell therapy in neurodegenerative disease, review preclinical data in Parkinson’s disease, and highlight clinical safety and efficacy data from the Phase 1 clinical trial of SNK01 in Alzheimer’s disease at the 12th Annual Alzheimer’s & Parkinson’s Drug Development Summit. The presentation will focus on enhancing natural killer cells to combat diseased cells and discuss the potential of NK cell therapy in treating neurodegenerative diseases.
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FAQ

What does NKGen Biotech, Inc. specialize in?

NKGen Biotech specializes in developing cell therapies for neurodegenerative and oncological diseases using activated NK cells.

What are SuperNK™ (SNK) cells?

SuperNK™ (SNK) cells are a proprietary product of NKGen Biotech, known for increased cytotoxicity and cytokine production compared to regular NK cells.

What recent achievements has NKGen Biotech accomplished?

The company has shown promising Phase 1 trial results for SNK01, indicating clinical activity in cognitive function for Alzheimer’s patients, alongside positive biomarker effects.

Where can I find the latest news about NKGen Biotech?

You can find the latest updates and detailed information on the NKGen Biotech website at https://nkgenbiotech.com/.

Who is overseeing the clinical trials for NKGen Biotech?

Dr. Jesse Carr, MD, Medical Director of Behavioral Research Specialists, LLC, is independently overseeing the SNK01 trial site.

Can SNK cells be produced in large quantities?

Yes, SNK cells can be produced in large quantities and cryopreserved while maintaining high levels of cytotoxicity.

Does NKGen Biotech have any partnerships?

NKGen Biotech collaborates closely with NKMAX, which conducts in vitro experiments to evaluate the activity of SNK cells.

What is the focus of NKGen Biotech’s ongoing projects?

The ongoing projects focus on developing SNK cell therapies for treating Alzheimer’s disease and various cancers.

Have there been any adverse events reported in the SNK01 trials?

No treatment-related adverse events have been reported in the SNK01 trials, which have shown preliminary clinical benefits.

What therapeutic areas is NKGen Biotech targeting?

NKGen Biotech is targeting neurodegenerative diseases like Alzheimer’s and oncological diseases using its SNK cell therapies.

NKGen Biotech, Inc.

Nasdaq:NKGN

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23.97M
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61.11%
12.79%
2.09%
Research and Development in Biotechnology
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